ID W7RM27_LYSSH Unreviewed; 127 AA.
AC W7RM27;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Anti-sigma factor antagonist {ECO:0000256|RuleBase:RU003749};
GN ORFNames=P799_16855 {ECO:0000313|EMBL:EWH31669.1};
OS Lysinibacillus sphaericus CBAM5.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Lysinibacillus.
OX NCBI_TaxID=1400869 {ECO:0000313|EMBL:EWH31669.1, ECO:0000313|Proteomes:UP000023555};
RN [1] {ECO:0000313|EMBL:EWH31669.1, ECO:0000313|Proteomes:UP000023555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBAM5 {ECO:0000313|EMBL:EWH31669.1};
RX PubMed=25685257; DOI=10.1186/1944-3277-10-2;
RA Pena-Montenegro T.D., Lozano L., Dussan J.;
RT "Genome sequence and description of the mosquitocidal and heavy metal
RT tolerant strain Lysinibacillus sphaericus CBAM5.";
RL Stand. Genomic Sci. 10:2-2(2015).
CC -!- FUNCTION: Positive regulator of sigma-B activity. Non-phosphorylated
CC RsbV binds to RsbW, preventing its association with sigma-B. When
CC phosphorylated, releases RsbW, which is then free to complex with and
CC inactivate sigma-B. {ECO:0000256|ARBA:ARBA00024670}.
CC -!- SIMILARITY: Belongs to the anti-sigma-factor antagonist family.
CC {ECO:0000256|ARBA:ARBA00009013, ECO:0000256|RuleBase:RU003749}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWH31669.1}.
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DR EMBL; AYKQ01000013; EWH31669.1; -; Genomic_DNA.
DR AlphaFoldDB; W7RM27; -.
DR HOGENOM; CLU_115403_9_3_9; -.
DR Proteomes; UP000023555; Unassembled WGS sequence.
DR GO; GO:0043856; F:anti-sigma factor antagonist activity; IEA:InterPro.
DR CDD; cd07043; STAS_anti-anti-sigma_factors; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR003658; Anti-sigma_ant.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00377; ant_ant_sig; 1.
DR PANTHER; PTHR33495; ANTI-SIGMA FACTOR ANTAGONIST TM_1081-RELATED-RELATED; 1.
DR PANTHER; PTHR33495:SF9; ANTI-SIGMA-B FACTOR ANTAGONIST; 1.
DR Pfam; PF01740; STAS; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
FT DOMAIN 35..127
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 127 AA; 14504 MW; D8BF7F56278A2024 CRC64;
MKQGTENSLT NMVEVCYMDV TIHFKEIDHK LFGFVEGEID TFTASGLREE LEAVKITEGM
EIELDLSKVN YMDSTGLGIF VAFYKRTLRE NGKVKLVGLS TRLQRLFEIT GLSDLMDIET
DKKVELR
//
