ID W7TJY4_9STRA Unreviewed; 558 AA.
AC W7TJY4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Kynurenine 3-monooxygenase {ECO:0000313|EMBL:EWM23823.1};
GN ORFNames=Naga_100623g2 {ECO:0000313|EMBL:EWM23823.1};
OS Nannochloropsis gaditana.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Eustigmatophyceae;
OC Eustigmatales; Monodopsidaceae; Nannochloropsis.
OX NCBI_TaxID=72520 {ECO:0000313|EMBL:EWM23823.1, ECO:0000313|Proteomes:UP000019335};
RN [1] {ECO:0000313|EMBL:EWM23823.1, ECO:0000313|Proteomes:UP000019335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B-31 {ECO:0000313|EMBL:EWM23823.1,
RC ECO:0000313|Proteomes:UP000019335};
RX PubMed=23966634; DOI=10.1093/mp/sst120;
RA Corteggiani Carpinelli E., Telatin A., Vitulo N., Forcato C., D'Angelo M.,
RA Schiavon R., Vezzi A., Giacometti G.M., Morosinotto T., Valle G.;
RT "Chromosome Scale Genome Assembly and Transcriptome Profiling of
RT Nannochloropsis gaditana in Nitrogen Depletion.";
RL Mol. Plant 7:323-335(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWM23823.1}.
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DR EMBL; AZIL01001443; EWM23823.1; -; Genomic_DNA.
DR AlphaFoldDB; W7TJY4; -.
DR EnsemblProtists; EWM23823; EWM23823; Naga_100623g2.
DR OrthoDB; 100857at2759; -.
DR Proteomes; UP000019335; Chromosome 15.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR46028; KYNURENINE 3-MONOOXYGENASE; 1.
DR PANTHER; PTHR46028:SF2; KYNURENINE 3-MONOOXYGENASE; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033, ECO:0000313|EMBL:EWM23823.1};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000313|EMBL:EWM23823.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019335};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 527..548
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 402..465
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 558 AA; 62299 MW; CC82B2A5669BD63F CRC64;
MPQLRLNSSN FCCTFVAVLF VSFFLSATCA FRFPRRTSAL LRHRTYAATS AFHPTSTNVH
LPASTAIVGA GPTGLFTALM LARRGYQNIT VYDRLPRPDD PSSPTWGNPY RSYNLGLGAR
GQIALRAADA WESIEPFCAQ AIGRKDWTPE QGERPEQIYT DREYKTQVIQ RDRIASCLLG
ELERKHGDQV SVWHNVECVG LTWLDEANPG PEASPSSAEI GEKGVRLRLH RQCEGQELEQ
WTTEARWVVG ADGVRSALRS ALEVKTAPGG HHGQTQKERV RTIKLPERNE FVYKILPLDL
RPKYGTGPGW RPDLNYSARS KGEVTIEALP TREGIFVGVV LFRPDSSAIA KIQGKEDARE
FFAGSFPQFL DVIREEDLAR FATGPTFRLP SFSYCGPSIF YRDNTLLLGD CIHSVKPYFG
LGLNSALEDV MALDKCLSES EDDVSKALPL FSSRTAPQAK ALVEFQASFD YNANTLEGFL
RFVLPLILDG IFHRYFPAFF APNGIRLLQD HRSTFRQTRR RKQRDRIGQA VILGVLLTGI
GKGLGWAVKV AARILLKG
//
