ID   W7TKZ0_9STRA            Unreviewed;       601 AA.
AC   W7TKZ0;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=E3 ubiquitin-protein ligase rnf8 {ECO:0000313|EMBL:EWM26742.1};
GN   ORFNames=Naga_100001g104 {ECO:0000313|EMBL:EWM26742.1};
OS   Nannochloropsis gaditana.
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Eustigmatophyceae;
OC   Eustigmatales; Monodopsidaceae; Nannochloropsis.
OX   NCBI_TaxID=72520 {ECO:0000313|EMBL:EWM26742.1, ECO:0000313|Proteomes:UP000019335};
RN   [1] {ECO:0000313|EMBL:EWM26742.1, ECO:0000313|Proteomes:UP000019335}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B-31 {ECO:0000313|EMBL:EWM26742.1,
RC   ECO:0000313|Proteomes:UP000019335};
RX   PubMed=23966634; DOI=10.1093/mp/sst120;
RA   Corteggiani Carpinelli E., Telatin A., Vitulo N., Forcato C., D'Angelo M.,
RA   Schiavon R., Vezzi A., Giacometti G.M., Morosinotto T., Valle G.;
RT   "Chromosome Scale Genome Assembly and Transcriptome Profiling of
RT   Nannochloropsis gaditana in Nitrogen Depletion.";
RL   Mol. Plant 7:323-335(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EWM26742.1}.
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DR   EMBL; AZIL01000609; EWM26742.1; -; Genomic_DNA.
DR   AlphaFoldDB; W7TKZ0; -.
DR   EnsemblProtists; EWM26742; EWM26742; Naga_100001g104.
DR   OrthoDB; 4593171at2759; -.
DR   Proteomes; UP000019335; Chromosome 8.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0006301; P:postreplication repair; IEA:InterPro.
DR   GO; GO:0006513; P:protein monoubiquitination; IEA:InterPro.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR039577; Rad18.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR14134; E3 UBIQUITIN-PROTEIN LIGASE RAD18; 1.
DR   PANTHER; PTHR14134:SF2; E3 UBIQUITIN-PROTEIN LIGASE RAD18; 1.
DR   Pfam; PF13920; zf-C3HC4_3; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019335};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT   TRANSMEM        577..594
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          412..456
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          32..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          236..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          270..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          534..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        236..251
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..293
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   601 AA;  65837 MW;  C4C05012AD4DA868 CRC64;
     MARRGLSHNL PNYVKGGCTV GACTYQSQAA RTFHDDDDDD SGGVGRDSTV LTTDTTTGER
     AEEVRVQSNA LKDANLSPVA TPAPHLSRDC TISAREVEEA SRILFAPEGA TSHFHHHRAE
     AAYQDSEANK LQKRVSGAAK TSERAPQVEA GIDEAVEDKQ RVNLAKGMAP TQSLPPMLRT
     RSPVSRSLAP LPSTLLARLH PQPEVHAEIL RFGEALASNP RIQNAIVEEL DMHYPPSRKA
     FEREGTGEND EGAAERSLAQ MESAVRRLLG RTSAEDRAEA ATQEGEEGNE ERRGFGSAGG
     GYSGRSSFLT DSFEVLGAMS AEWSSASSKN GGAEEKVGNE REDMAENLPS NSFVSVGRYM
     RRKDSLAGEV SDEVLDELLR SEDDDDVIAQ KLFAETPDDQ VRRFLRNLDL ECVICHEYMV
     EAAAVDCGEG HTFCGECIER WLELPVAGGS RCPTCQKPVH STIPMRQYDA MIEKYVRASN
     LWDEQCSFYR RRTLAHMRRE MERQDREEEE TATAATQGPF AGIGNLFGLG TRANARRQRR
     RSRRATAAAT RAAAGASRTT GDGGAGEAAQ PWWKSELLST ALSVATMLVL LVLFKRGFKT
     R
//