ID W8B4L5_CERCA Unreviewed; 2666 AA.
AC W8B4L5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Dynein heavy chain 7, axonemal {ECO:0000313|EMBL:JAB88231.1};
DE Flags: Fragment;
GN Name=DYH7 {ECO:0000313|EMBL:JAB88231.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB88231.1};
RN [1] {ECO:0000313|EMBL:JAB88231.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB88231.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
CC -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC {ECO:0000256|ARBA:ARBA00008887}.
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DR EMBL; GAMC01018326; JAB88229.1; -; mRNA.
DR EMBL; GAMC01018324; JAB88231.1; -; mRNA.
DR GO; GO:0005929; C:cilium; IEA:UniProt.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF1; DYNEIN HEAVY CHAIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 2: Evidence at transcript level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 2..267
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 438..570
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 789..877
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 950..1211
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 1237..1565
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 1598..1819
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 2064..2177
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 2213..2352
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 2360..2662
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT COILED 1468..1516
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAB88231.1"
SQ SEQUENCE 2666 AA; 303122 MW; F7CF997347318AF5 CRC64;
KVFNCSDGLD YKAMGKFFKG LASCGAWACF DEFNRIELEV LSVVAQQILL IIQAVRAKAV
KFNFEGTELT LNPACYVCIT MNPGYAGRSE LPDNLKVLFR SVAMMVPDYA MIGEISLYSY
GFVDARKLSV KIVTTYRLCS EQLSMQNHYD YGMRAVKTVL SACGNLKKKF PNEMEDILLL
RSLLDVNLPK FMSFDIPLFE GIISDIFPGV VLPETDYSLI ETEFVRICGE MILEPTESFL
TKVIQTYEMI IVRHGFMMVG EPLAGKSKTL QVLAHVLSAL KIKAPSKSQY FQHVQMGIMN
PKSITMNQLY GSFDPVSYEW NDGIIAKIFR EFAMTPTPDR KWVIFDGPVD AVWIENMNTV
LDDNKKLCLN SGEVITMSNE MSMIFEVMDL AQASPATVSR CGMIYMETAS LGWRSFANCW
LRKCNPIWAD EETQEYIMEF LKWLLEPCQA FIRRNCKEHI KPGEFNCLTT TFDIIEMLLD
NAVVENPDEY QRHMPIYVQA SILYSFVWGL AGVLDTGSRE KFDAFIKSLW LSEDIPEKIG
KLEISVPVEG LLVDYVYVFK QRGAWKSWTE LAKRMDVEEN SMGVQVPTID TARYIHILEM
HIKNNKKMLL VGPTGTGKSA YIQNYLMNKI DRDAIESAFM TFTVMITANQ TQELLISKLV
KWKRGIYGPP KGMKTVLFVD DMNMPVKEIY GAQPPLELLR QYFDYGHVYD LKDTSKIFIN
DLLVLTACGL PGGSRQDVYA RFLNHFNVFS INTFGDDTMN RIFVNVLMNG FKRSGHGNDV
FASTNQIVNA TQQIYKSVQA ELRATPAKSH YIFNLRDIAR VVSACALFKK ESVSDKKMFP
RLWYHEAMRV FYDRLVDDAD REWMFQKFND CIKNNFKEKL ETVFENYCTN VGGEMTFTIE
GAHRIFFGAF MDEDNLPDER RYEELPSMEV FFKYAATSLE DYNSTRRSKM DITLFTFALE
HLNRICRIIA INGASALLIG MGGSGRQSLT KLASNMVQTS FFQPEITKNY GPNDWHDDIK
NIMKESGGLN KHTVFLMTEN QIKMELFLQD IDCLLNQGEV PNVYAIDEKQ EILELVRLAA
QGGNRNIDIS PLQVFSFFVN RCKQKLHIVL CLSPIGDALR TRVRLYPSLV SCCTIDWYQS
WPEEALTMIA KISLEGVNVP STDIKDSIVQ ICQYFHISAA KVCREFCELT GRHIYQTNAS
FLELIKSFQN LIGRKQKEIM EAKMRYIGGL DTLANAAAAI ALMQKELNAL QPQLVALAEK
SRQMLIEINK ETIAASVAAE QVKKDEAVAA VQAEAAQGLK DECEKDLAQA IPVLEEAIQA
LNTLKPADIT LVKSMKNPPP VIKLVMAAVC VIKGVPPERI PDPSTGKMVN DYWGPSKRIL
GEMNFLQQLK DFDKDNIKPE IMARIRKEFI PNKDFQPKIV AKASSAAEGL CKWIIAMDLY
DNVAKVVAPK KAKLAAAEKE YSDTMKFLNE KRELAAALEA KVAKLNEELD NANAEMKRTQ
DEADFCQSKL ERATALIDGL GGEKARWTQA AENLQGIYDN LPGDILLSCG IIAYLSAVNL
YYRTKCTTDW FKRCTQAGIP TSKEYNITTT LGLEITIQNW NINGLPKDVF STENAIIADS
SSRYSLFIDP QGQANSWIKN MERKNRLSSV KFNQANYMKV IAECMEYGSP VIIENVLEEL
EVPLDPILMR KTFKQGGQNF ISLGDNIVPL SDNFRLYMTC NLRNPHFLPE TFNKVTIINF
ALTQNALEDQ LLSIVVAKER PDLQELRMML INEAAKNKAA LRDAENMILK TLSSAEGDIL
ENESAIQILN ESKELSLDIV AKQTASRETE MKIEAFRLNY KPVAVHSSVL YYSITDLPNI
DPMYQFSLNW YINLYEYSIE SANKSKDLPR RIKFLVDGVT RNLYNNVCRS IFEKDKLLFS
FILTCRILLG TGQLRMVQLS HLLTDAKESD KISTNPDQSW ITDILWMNVV RLEELPELRG
FAASFAKGLN DWKRIYDHVE PENQVIPSPW NEKLTRFEKI LVLKALRPDK VFIAIRNFIA
AEMGTQFVTP PEFDIGMSYK ESNALTPLIF ILSPGADPLG SLLAYAEKAG FMETFQSISL
GQGQGPIALG LIKDAQDLGY WVCLQNCHLA ASWMPTLEYA WENMDTFNTS PSFRLWLTSY
PTPKFPVALL QNGVKMTNEP PTGLKENIMR SYNSEPINDP TFYLGCAKQD RAFTRLLFGI
CFFHAVVQER RKYGPLGWNI SYGFNESDLQ ISVLQLNMLL NQYDHVPYDA LSYLTAECNY
GGRVTDYWDR RAIITILADY LNADVVNDNR YRFATDDRFI LPRKTEHREI LRYVDENYPS
LAAPEVYGLH GNSGITRDLQ TTRTLLDSMV AIIGSEMATS GAGTQSQDET LLQTINHIAK
TMPSDMDIDH AKAKYPVNYN ESMNTVLVQE MERFLKLQKE IRASCRDLDM AIKGIVVMTP
ELENVLNAIK LNRIPVKWLS KSYPSLKTLG SYINDLYKRL DWLQHWYAHG KPPTFWLSGF
FFTQAFLTGA MQNFARKYKI PIDTLTFDFE VLYEESMESP PADGVYVNGL FLEGARWNLK
NNIIDEQLPK VLIYTMPAIY FKPMVILSLI EGTRYKCPLY KTSERKGVLS TTGHSTNYVI
PILLKTKVKA THWIKRSAAL LCQKTD
//
