ID W8BVW8_CERCA Unreviewed; 680 AA.
AC W8BVW8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Metabotropic glutamate receptor {ECO:0000313|EMBL:JAC03378.1};
DE Flags: Fragment;
GN Name=GRM {ECO:0000313|EMBL:JAC03378.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAC03378.1};
RN [1] {ECO:0000313|EMBL:JAC03378.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAC03378.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GAMC01003178; JAC03378.1; -; mRNA.
DR AlphaFoldDB; W8BVW8; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd13953; 7tm_classC_mGluR-like; 1.
DR InterPro; IPR017978; GPCR_3_C.
DR PANTHER; PTHR24060:SF177; LP07906P; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:JAC03378.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 196..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 234..488
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..614
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAC03378.1"
SQ SEQUENCE 680 AA; 72466 MW; 7E69BC7EA7091862 CRC64;
NTNTNTNIAS PSGKVSARTT TSNTSKEVNI PRSGKTSTES GVSVSVEPKT DLYTMDYKDV
PISGIQQRHG KQLSRREDTN IGGLLLDTTT FSSKDSNISK ADRLVVMSTE FFVVPSSTPL
PRNAGTPVRT GAKAAVLPAY IQPPPEGAPT AGPRSVLIVA PRPANSSNSA NTLGAGAPPS
IIPTHLPFTG LRKEPWVVPV LVLAALTMLM MTAFEIFVLF KAWRTSPSRR HLFLGQMLLL
GLFACAGLGA VLTAQPSLLS CGTIRFGVGV AYALVFAALL VKCVFLISLN GGVYLPAPYQ
GLLLLFAVLI QVAIGTQWLL TQPPEIYTQS VPILGNSLLA PTVASISATS AAHTFAALFQ
PQNPTNINGP TPAAMSANLG ADIYARITTA GTVLIPLCKT QFSELLFSLI YIVFLIVFVA
VLAIKSRGIR DNYREATYIG LAIGGAIPIW LGWMLCGLAV ADRHKDACIA FGLIATSATV
FLVMFMPKGR QLAAMGKEGL YVEDREEQFS SLSRAGSGYS PSFFHFKPIK YGVMGGGMQN
SATNTGNGAS MKHCSNGLGG GDRVALVTAA PPSYTRMYHY FPAHLSAHPF CFYPQPPPPP
PPPPIPPPTL TQLPSPPTLK QLGNSLSSMT QAHIAQTLRY PGLFIRPDET NLYTTLEPTL
SSNPNVYFQR GGAVHPGMMY
//
