ID W8C0C2_CERCA Unreviewed; 2074 AA.
AC W8C0C2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 26 {ECO:0000256|ARBA:ARBA00019686};
DE AltName: Full=Mediator complex subunit 26 {ECO:0000256|ARBA:ARBA00031968};
GN Name=MED26 {ECO:0000313|EMBL:JAC02459.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAC02459.1};
RN [1] {ECO:0000313|EMBL:JAC02459.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAC02459.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 26 family.
CC {ECO:0000256|ARBA:ARBA00009681}.
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DR EMBL; GAMC01004097; JAC02459.1; -; mRNA.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR042376; MED26.
DR InterPro; IPR003617; TFIIS/CRSP70_N_sub.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR15201; CRSP70; 1.
DR PANTHER; PTHR15201:SF1; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26; 1.
DR Pfam; PF08711; Med26; 1.
DR SMART; SM00509; TFS2N; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 2: Evidence at transcript level;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}.
FT DOMAIN 8..85
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 107..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 695..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 849..875
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1236..1264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..865
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1236..1251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2074 AA; 230917 MW; E3F3A30D6E9A6F26 CRC64;
MNTKNIHELT SHLCQALDQN YDVVNMGAVM LVISTLEGTT ITKEQLETTR LAKFINHLRR
RTKDDHLARR AKSLLKKWRE MVGIQQQPQV IDTTPINLSA ALPSGSGYST SLSQQQRFRS
QSISPSASSI HFEQHHSNSN SSQTIPASTI LSEHIQHATS VSTHSLTPIA ESANPVTHYN
KKRFGTCQNQ NETHIISKQP TSFENVLIGF GVTDNNLSIT SDSSRFCSKL SQSAQQHVIP
SDNTGAFIID QSSNSNSQMS LILPSSNRPP VLAPIVIDIQ DSNSGSDLSA SVLNATLNSK
MPLCDPGRAQ NVSLASSLSI PGLQSQFPSK SKKIKKEKKR KDKSQYSVHE TEVTSNAKDT
TVLVDETSSN QNCRLLSEEN SDKYSPFVND EKSRLAYPEI LSLLDNSSMS SMFPPESSPN
PVDEQSKVNL SANDSLRTTF NLSLSDLSFA GKFKQGAALF PTSNELTGYK SHRPASIQTG
PTHSKFTPFR GARSNSNDSN SQVSQPDLIE VISSDKMQGF QTQAKQGTLN LQYKTASTSS
MSQQPVAATV TTAQQTKSII QIETSGPGIS RVCVAPEQKI PRKRGRKKGS KGVDSIIAKE
TSLSSQILMT TLGTGGKKVK TTKELYVEMQ NRKLGITSTL SSPTLIGLQA QQQLQVSRPT
SSCSEPSLQS PHIFDLCSPN ASMSTVAARS TQENCLINPN AGDGESTSET GTSDPSRDSS
RIFKQPKRSL SIDSNSNSPQ FPSMKASYNS IPSIDHQIAD IEKQLHEVMS NLPIVPDIAG
IELKCSTEKV PCTCKVIELF PPSNDVEVSV QEEQSEMQTE VTDGKNYMQN VSTDQIAEKF
DKLQTATENI NVPKETGSNQ VSTSPSLPPP DRPNLKKSIF DFDFEDDEDP LHTLKAEAAA
TKQREKEPSN SIEVIDVLEI NALNVHQIEQ QQHQPLEFKI SIAPVLTQFM KETPMTKFPT
YEVEEDAQCI AKQRFHLQTQ KITKFHIDAL HNCFIPNVNG NWDDTNNRLA QSNVLGVFTG
AGDVENEYAV TDGYSVVPKY GSLVMERICK DLSHIQFSEN FKPTEDASTG AKHLYILPFL
GVARSVLTKV VKRKRHSHKI CHKTEVTAFS ACVYDKKARA ASKIKANREF EHYKTDKGNF
EFGLQIRDNQ ISTVQQGSMF HLGKTLDIEA DSVVNKNINS ATLKDITIDV IDHGSRIFLT
QPNELSGEAG QNLLAIADHL DYGSKLTSLS QNNTITDSNN AGFQNNVEDL HRSSNPETDE
KKSGYGCKSI SSLFPVKLLS EFNEKNTTQV EKLDENASSR QSSSCSSSSL RQAQNSINLK
LKRQLHEQKL LDISGEGNHL RQKNSLWFPL NKLNEENKQP KVKRIKIAVN RNIATEMQIL
AGSSNISMVE NNNEKCIDND KFHEENEHTS KGFVGHENVE SVNSVGSRIS ICNKLNERST
DDVRINCREN CNDNQEVDYG ENDVNADVVF DEYEDSEDYS SDYHEFVTRN ISVPSTGSNH
IVLTIKKTPS KTKSPSKSFS AMSPVIASNI TSSSQAAGIA TVISKTSCAP NLNYANKDML
VVSKTEAGET KANTTTAESL EEIKEVKRNH SQSDIWDNHA NISSTSFLQN VETISRIQSL
PSGQHENFIS TSYRHLKLPK YKKYLKPNKR HRGKNIENGN GKFSHVKLHH ELFFPHELVI
SDCYGSKRNI LNFSSCSSSC GEHSEYEENE EYVGMNHISE EDFNDRTFSE AVVNSETDNI
NICGIQQHWD SDLSTSPCST YSTCSTCDSK SNNYVQTESY NYKGCFDRIV QSSDYSLDTN
EEISHTLADD NIAKSINEEL PLENNGLLHS FNNIYTKVDK LEAKTTDTTI QNDNIVAFMA
GSHMICDNKT VDPATVDAEK QQEQMRRNKN CDDYNNIYNN NKNSNNINLI RYYINEPSLI
TQVNRNEQSD IHNEDDQHEK ESHLDVVNVF NANTDADFFD TSLNIDNYDK NTNTSNVDRT
LFMEHSAKAD QITNSSYTNR SEKLTQSSFF KSHCVHMLSH KENRTGLRAV DVDVNDDDGN
NCARIQQFKE WHQVLQLRSY NEELLTVLPY VVLD
//
