ID W8C140_CERCA Unreviewed; 369 AA.
AC W8C140;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=(Mediterranean fruit fly) hypothetical protein {ECO:0000313|EMBL:CAD6993786.1};
DE SubName: Full=E3 ubiquitin-protein ligase RNF146-A {ECO:0000313|EMBL:JAB99431.1};
GN Name=R146A {ECO:0000313|EMBL:JAB99431.1};
GN ORFNames=CCAP1982_LOCUS2584 {ECO:0000313|EMBL:CAD6993786.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB99431.1};
RN [1] {ECO:0000313|EMBL:JAB99431.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB99431.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
RN [3] {ECO:0000313|EMBL:CAD6993786.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EGII {ECO:0000313|EMBL:CAD6993786.1};
RA Whitehead M.;
RL Submitted (NOV-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CAJHJT010000001; CAD6993786.1; -; Genomic_DNA.
DR EMBL; GAMC01007124; JAB99431.1; -; mRNA.
DR EMBL; GAMC01007123; JAB99432.1; -; mRNA.
DR RefSeq; XP_012161713.1; XM_012306323.1.
DR AlphaFoldDB; W8C140; -.
DR EnsemblMetazoa; XM_012306323.2; XP_012161713.1; LOC101455597.
DR GeneID; 101455597; -.
DR OrthoDB; 209481at2759; -.
DR Proteomes; UP000606786; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047134; RNF4.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR23041:SF78; E3 UBIQUITIN-PROTEIN LIGASE RNF4; 1.
DR PANTHER; PTHR23041; RING FINGER DOMAIN-CONTAINING; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000606786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 316..356
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 35..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..98
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 39881 MW; 3424DB54472940D8 CRC64;
MSISGKNLSL SPEADLDELI QDTSLLIASV YDMFGRPQRS PRPAQTILGR RSHNNSDNSG
QFGSSSNTSN SSTPKSPKTP RLGNSNRAVP STPSSREIDQ EINRIDRFCE MLEHNLRSSS
GEQNQMVRGP LGLASPTSPR NRAGRRSLES AAANAARSPT VEEVIDLCDS MSMPAPLARR
ALNLSDDVII VTPTDDEIVD LCTPNHRRNT ARTRNINSNR RSINFNGSTN NCRSGNESRP
RMRASSRSLS SSNSSAHCSN EGRSSRCSIS TTTSTTNINP SATAATKVAS KKKSPGANCD
DADDGANGDG RVPFMCAVCM ESCVSNQPTS TKCGHVFCAN CIRQAVRLTR KCPMCNTKLT
ANMLFRIYV
//
