ID W8UEE4_KLEPN Unreviewed; 230 AA.
AC W8UEE4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Semialdehyde dehydrogenase NAD-binding domain-containing protein {ECO:0000259|SMART:SM00859};
GN ORFNames=KPNJ2_00630 {ECO:0000313|EMBL:AHM77410.1};
OS Klebsiella pneumoniae 30684/NJST258_2.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=1420013 {ECO:0000313|EMBL:AHM77410.1, ECO:0000313|Proteomes:UP000019586};
RN [1] {ECO:0000313|EMBL:AHM77410.1, ECO:0000313|Proteomes:UP000019586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=30684/NJST258_2 {ECO:0000313|EMBL:AHM77410.1};
RX PubMed=24639510; DOI=10.1073/pnas.1321364111;
RA Deleo F.R., Chen L., Porcella S.F., Martens C.A., Kobayashi S.D.,
RA Porter A.R., Chavda K.D., Jacobs M.R., Mathema B., Olsen R.J., Bonomo R.A.,
RA Musser J.M., Kreiswirth B.N.;
RT "Molecular dissection of the evolution of carbapenem-resistant multilocus
RT sequence type 258 Klebsiella pneumoniae.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:4988-4993(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP006918; AHM77410.1; -; Genomic_DNA.
DR AlphaFoldDB; W8UEE4; -.
DR KEGG; kps:KPNJ2_00630; -.
DR PATRIC; fig|1420013.3.peg.600; -.
DR HOGENOM; CLU_071330_2_0_6; -.
DR Proteomes; UP000019586; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR PANTHER; PTHR14097; OXIDOREDUCTASE HTATIP2; 1.
DR PANTHER; PTHR14097:SF7; OXIDOREDUCTASE HTATIP2; 1.
DR Pfam; PF13460; NAD_binding_10; 1.
DR SMART; SM00859; Semialdhyde_dh; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
FT DOMAIN 18..118
FT /note="Semialdehyde dehydrogenase NAD-binding"
FT /evidence="ECO:0000259|SMART:SM00859"
SQ SEQUENCE 230 AA; 24987 MW; 6A793123B09E1607 CRC64;
MSLKVQGGEF CKGEPMSQVL LTGATGLVGG HLLRLLQNEP RISTIAAPTR RPLAPAEGVF
NPHDPQLTDA LAQVVDPVDI VFCCLGTTRR EAGSKEAFVH ADYTLVVDTA LTGKRLGAQH
MLVVSAMGAN AHSPFFYNRV KGEMEAALIE QDWPRLTIAR PSMLSGEREK KRANETFLAP
LFRLLPGNWK SIAARDVAIA LLAEALSPTH EGVRILTSSE LRERAARQAE
//
