ID W8UV97_KLEPN Unreviewed; 610 AA.
AC W8UV97;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Propanediol dehydratase reactivation protein PduG {ECO:0000313|EMBL:AHM77847.1};
GN ORFNames=KPNJ2_01067 {ECO:0000313|EMBL:AHM77847.1};
OS Klebsiella pneumoniae 30684/NJST258_2.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=1420013 {ECO:0000313|EMBL:AHM77847.1, ECO:0000313|Proteomes:UP000019586};
RN [1] {ECO:0000313|EMBL:AHM77847.1, ECO:0000313|Proteomes:UP000019586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=30684/NJST258_2 {ECO:0000313|EMBL:AHM77847.1};
RX PubMed=24639510; DOI=10.1073/pnas.1321364111;
RA Deleo F.R., Chen L., Porcella S.F., Martens C.A., Kobayashi S.D.,
RA Porter A.R., Chavda K.D., Jacobs M.R., Mathema B., Olsen R.J., Bonomo R.A.,
RA Musser J.M., Kreiswirth B.N.;
RT "Molecular dissection of the evolution of carbapenem-resistant multilocus
RT sequence type 258 Klebsiella pneumoniae.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:4988-4993(2014).
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DR EMBL; CP006918; AHM77847.1; -; Genomic_DNA.
DR RefSeq; WP_004151974.1; NZ_CP006918.1.
DR AlphaFoldDB; W8UV97; -.
DR KEGG; kps:KPNJ2_01067; -.
DR PATRIC; fig|1420013.3.peg.1021; -.
DR HOGENOM; CLU_449540_0_0_6; -.
DR Proteomes; UP000019586; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 3.90.470.30; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.50.30.70; Swiveling domain of dehydratase reactivase alpha subunit; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR030994; DDR_dom.
DR InterPro; IPR040916; DDR_swiveling.
DR InterPro; IPR009191; DDRA.
DR InterPro; IPR028975; DDRA_swiveling_dom_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04491; reactive_PduG; 1.
DR Pfam; PF08841; DDR; 1.
DR Pfam; PF18427; DDR_swiveling; 1.
DR PIRSF; PIRSF011502; DdrA_PduG; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF82317; Swiveling domain of dehydratase reactivase alpha subunit; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR011502-2};
KW Magnesium {ECO:0000256|PIRSR:PIRSR011502-1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR011502-1};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR011502-2}.
FT DOMAIN 93..254
FT /note="DD-reactivating factor swiveling"
FT /evidence="ECO:0000259|Pfam:PF18427"
FT DOMAIN 275..601
FT /note="Diol dehydratase reactivase ATPase-like"
FT /evidence="ECO:0000259|Pfam:PF08841"
FT BINDING 11..13
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-2"
FT BINDING 105
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-1"
FT BINDING 166
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-1"
FT BINDING 183
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-1"
FT BINDING 459..462
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-2"
FT BINDING 557..558
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-2"
FT BINDING 591
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-2"
SQ SEQUENCE 610 AA; 63831 MW; A75486CF631A6D4D CRC64;
MRYIAGIDIG NSSTEVALAT VDDAGVLNIR HSALAETTGI KGTLRNVFGI QEALTQAAKA
AGIQLSDISL IRINEATPVI GDVAMETITE TIITESTMIG HNPKTPGGVG LGVGITITPE
ALLSCSADTP YILVVSSAFD FADVAAMVNA ATAAGYQITG IILQQDDGVL VNNRLQQPLP
VIDEVQHIDR IPLGMLAAVE VALPGKIIET LSNPYGIATV FDLNAEETQN IVPMARALIG
NRSAVVVKTP SGDVKARAIP AGNLLLIAQG RSVQVDVAAG AEAIMKAVDG CGKLDNVAGE
AGTNIGGMLE HVRQTMAELT NKPAQEIRIQ DLLAVDTAVP VSVTGGLAGE FSLEQAVGIA
SMVKSDRLQM ALIAREIEHK LQIAVQVGGA EAEAAILGAL TTPGTTRPLA ILDLGAGSTD
ASIINAQGEI SATHLAGAGD MVTMIIAREL GLEDRYLAEE IKKYPLAKVE SLFHLRHEDG
SVQFFPSALP PTVFARVCVV KPDELVPLPG DLPLEKVRAI RRSAKSRVFI TNALRALRQV
SPTGNIRDIP FVVLVGGSSL DFEIPQLVTD ALAHYRLVAG RGNIRGCEGP RNAVASGLLL
SWQKGGTHGE
//
