ID W9BD65_KLEPN Unreviewed; 636 AA.
AC W9BD65; A0A0J2G4I6;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=BglB-family transcriptional antiterminator {ECO:0000313|EMBL:VGJ40159.1};
DE SubName: Full=BglG family transcription antiterminator {ECO:0000313|EMBL:QLI10723.1};
DE SubName: Full=LicABCH operon regulator {ECO:0000313|EMBL:VCX99961.1};
DE SubName: Full=PRD domain-containing protein {ECO:0000313|EMBL:MUA40359.1};
GN Name=licR {ECO:0000313|EMBL:VGJ40159.1};
GN ORFNames=BANRA_04633 {ECO:0000313|EMBL:VCX99961.1}, BL124_00000560
GN {ECO:0000313|EMBL:ROH05629.1}, DW281_21755
GN {ECO:0000313|EMBL:RDT85801.1}, EAO17_16570
GN {ECO:0000313|EMBL:RRF07707.1}, FXN67_11680
GN {ECO:0000313|EMBL:TYL79299.1}, G7Z27_24450
GN {ECO:0000313|EMBL:QLI10723.1}, GJJ08_024135
GN {ECO:0000313|EMBL:QOU51369.1}, GNF00_10910
GN {ECO:0000313|EMBL:MUA40359.1}, GS419_24260
GN {ECO:0000313|EMBL:QHD77086.1}, NCTC13635_04640
GN {ECO:0000313|EMBL:VEB04696.1}, NCTC5052_02556
GN {ECO:0000313|EMBL:STT94132.1}, NCTC9140_01407
GN {ECO:0000313|EMBL:STS79722.1}, NCTC9601_05425
GN {ECO:0000313|EMBL:SQC18527.1}, SAMEA3499874_03465
GN {ECO:0000313|EMBL:SXG17330.1}, SAMEA3512100_04228
GN {ECO:0000313|EMBL:SXU35440.1}, SAMEA3538658_03322
GN {ECO:0000313|EMBL:SYK82411.1}, SAMEA3720909_03802
GN {ECO:0000313|EMBL:SWF74783.1}, SAMEA4370542_03487
GN {ECO:0000313|EMBL:SLS63981.1}, SAMEA4873597_03967
GN {ECO:0000313|EMBL:VGJ40159.1};
OS Klebsiella pneumoniae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=573 {ECO:0000313|EMBL:VGJ40159.1, ECO:0000313|Proteomes:UP000295133};
RN [1] {ECO:0000313|EMBL:RRF07707.1, ECO:0000313|Proteomes:UP000275975}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KLPN_104 {ECO:0000313|EMBL:RRF07707.1,
RC ECO:0000313|Proteomes:UP000275975};
RX PubMed=30373801;
RA Tamma P.D., Fan Y., Bergman Y., Pertea G., Kazmi A., Lewis S.,
RA Carroll K.C., Schatz M.C., Timp W., Simner P.J.;
RT "Applying Rapid Whole Genome Sequencing to Predict Phenotypic Antimicrobial
RT Susceptibility Testing Results Among Carbapenem-Resistant Klebsiella
RT pneumoniae Clinical Isolates.";
RL Antimicrob. Agents Chemother. 0:0-0(2018).
RN [2] {ECO:0000313|Proteomes:UP000251123, ECO:0000313|Proteomes:UP000254103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC5052 {ECO:0000313|EMBL:STT94132.1,
RC ECO:0000313|Proteomes:UP000254103}, NCTC9140
RC {ECO:0000313|EMBL:STS79722.1, ECO:0000313|Proteomes:UP000254938}, and
RC NCTC9601 {ECO:0000313|EMBL:SQC18527.1,
RC ECO:0000313|Proteomes:UP000251123};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:RDT85801.1, ECO:0000313|Proteomes:UP000254680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K280 {ECO:0000313|EMBL:RDT85801.1,
RC ECO:0000313|Proteomes:UP000254680};
RA He F.;
RT "Draft genome sequence of Klebsiella pneumoniae K280.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:ROH05629.1, ECO:0000313|Proteomes:UP000283322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRK0165 {ECO:0000313|EMBL:ROH05629.1,
RC ECO:0000313|Proteomes:UP000283322};
RA Vanduin D., Fouts D., Wright M., Sutton G., Nguyen K., Kreiswirth B.,
RA Chen L., Rojas L., Hujer A., Hujer K., Bonomo R., Adams M.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:VCX99961.1, ECO:0000313|Proteomes:UP000278966}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Kpneu025 {ECO:0000313|EMBL:VCX99961.1};
RA Noll B N.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:VGJ40159.1, ECO:0000313|Proteomes:UP000295133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5012STDY7626396 {ECO:0000313|EMBL:VGJ40159.1,
RC ECO:0000313|Proteomes:UP000295133}, EuSCAPE_AT002
RC {ECO:0000313|EMBL:SXG17330.1, ECO:0000313|Proteomes:UP000257587},
RC EuSCAPE_DE072 {ECO:0000313|EMBL:SXU35440.1,
RC ECO:0000313|Proteomes:UP000259753}, EuSCAPE_IT290
RC {ECO:0000313|EMBL:SYK82411.1, ECO:0000313|Proteomes:UP000258808},
RC EuSCAPE_UK014 {ECO:0000313|EMBL:SWF74783.1,
RC ECO:0000313|Proteomes:UP000259364}, NCTC13635
RC {ECO:0000313|EMBL:VEB04696.1, ECO:0000313|Proteomes:UP000282433}, and
RC VRES1272 {ECO:0000313|EMBL:SLS63981.1,
RC ECO:0000313|Proteomes:UP000191996};
RG Pathogen Informatics;
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:TYL79299.1, ECO:0000313|Proteomes:UP000322977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCO-494 {ECO:0000313|EMBL:TYL79299.1,
RC ECO:0000313|Proteomes:UP000322977};
RA Morales-Leon F., Caro C., Opazo-Capurro A., Lincopan N.,
RA Dominguez-Yevenes M., Lima C., Bello-Toledo H., Gonzalez-Rocha G.;
RT "Phenotypic and genetic characterization of extended-spectrum b-lactamase-
RT producing hypermucoviscous Klebsiella pneumoniae from Chile.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:MUA40359.1, ECO:0000313|Proteomes:UP000485085}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KP_38044 {ECO:0000313|EMBL:MUA40359.1,
RC ECO:0000313|Proteomes:UP000485085};
RA Zhou K.;
RT "Emergence of a novel subclone of carbapenem-resistant Klebsiella
RT pneumoniae ST11 with enhanced virulence and transmissibility: a molecular
RT epidemiological, clinical, genomic study.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
RN [9] {ECO:0000313|EMBL:QHD77086.1, ECO:0000313|Proteomes:UP000464108}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Kp36 {ECO:0000313|EMBL:QHD77086.1,
RC ECO:0000313|Proteomes:UP000464108};
RA Tan D.;
RT "Mobile Genetic Element-Mediated Frameshifting in wcaJ Provides Phage
RT Resistance in Klebsiella pneumoniae.";
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
RN [10] {ECO:0000313|EMBL:QOU51369.1, ECO:0000313|Proteomes:UP000439817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CriePir120 {ECO:0000313|EMBL:QOU51369.1,
RC ECO:0000313|Proteomes:UP000439817};
RX PubMed=32429555;
RA Shelenkov A., Mikhaylova Y., Yanushevich Y., Samoilov A., Petrova L.,
RA Fomina V., Gusarov V., Zamyatin M., Shagin D., Akimkin V.;
RT "Molecular Typing, Characterization of Antimicrobial Resistance, Virulence
RT Profiling and Analysis of Whole-Genome Sequence of Clinical Klebsiella
RT pneumoniae Isolates.";
RL Antibiotics 9:E261-E261(2020).
RN [11] {ECO:0000313|EMBL:QLI10723.1, ECO:0000313|Proteomes:UP000509467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=11KM256 {ECO:0000313|EMBL:QLI10723.1,
RC ECO:0000313|Proteomes:UP000509467};
RA Brilhante M., Perreten V.;
RT "Whole genome sequencing of global problem clones of OXA-48-producing
RT Klebsiella pneumoniae from the veterinary setting in Switzerland.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; WNPO01000015; MUA40359.1; -; Genomic_DNA.
DR EMBL; CP047192; QHD77086.1; -; Genomic_DNA.
DR EMBL; CP049716; QLI10723.1; -; Genomic_DNA.
DR EMBL; CP063008; QOU51369.1; -; Genomic_DNA.
DR EMBL; QRCD01000027; RDT85801.1; -; Genomic_DNA.
DR EMBL; MPYG04000004; ROH05629.1; -; Genomic_DNA.
DR EMBL; RDAM01000001; RRF07707.1; -; Genomic_DNA.
DR EMBL; FWJM01000011; SLS63981.1; -; Genomic_DNA.
DR EMBL; UASN01000022; SQC18527.1; -; Genomic_DNA.
DR EMBL; UGKQ01000007; STS79722.1; -; Genomic_DNA.
DR EMBL; UGLJ01000002; STT94132.1; -; Genomic_DNA.
DR EMBL; UJHH01000018; SWF74783.1; -; Genomic_DNA.
DR EMBL; UKAW01000009; SXG17330.1; -; Genomic_DNA.
DR EMBL; UKLK01000009; SXU35440.1; -; Genomic_DNA.
DR EMBL; UKXO01000012; SYK82411.1; -; Genomic_DNA.
DR EMBL; VSSY01000008; TYL79299.1; -; Genomic_DNA.
DR EMBL; UWWS01000001; VCX99961.1; -; Genomic_DNA.
DR EMBL; LR134162; VEB04696.1; -; Genomic_DNA.
DR EMBL; CAAHAW010000011; VGJ40159.1; -; Genomic_DNA.
DR RefSeq; WP_004152270.1; NZ_WXZO01000006.1.
DR KEGG; kpne:KU54_024095; -.
DR KEGG; kpnk:BN49_4795; -.
DR KEGG; kpnu:LI86_23935; -.
DR Proteomes; UP000191996; Unassembled WGS sequence.
DR Proteomes; UP000251123; Unassembled WGS sequence.
DR Proteomes; UP000254103; Unassembled WGS sequence.
DR Proteomes; UP000254680; Unassembled WGS sequence.
DR Proteomes; UP000254938; Unassembled WGS sequence.
DR Proteomes; UP000257587; Unassembled WGS sequence.
DR Proteomes; UP000258808; Unassembled WGS sequence.
DR Proteomes; UP000259364; Unassembled WGS sequence.
DR Proteomes; UP000259753; Unassembled WGS sequence.
DR Proteomes; UP000275975; Unassembled WGS sequence.
DR Proteomes; UP000278966; Unassembled WGS sequence.
DR Proteomes; UP000282433; Chromosome 1.
DR Proteomes; UP000283322; Unassembled WGS sequence.
DR Proteomes; UP000295133; Unassembled WGS sequence.
DR Proteomes; UP000322977; Unassembled WGS sequence.
DR Proteomes; UP000439817; Chromosome.
DR Proteomes; UP000464108; Chromosome.
DR Proteomes; UP000485085; Unassembled WGS sequence.
DR Proteomes; UP000509467; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR CDD; cd00211; PTS_IIA_fru; 1.
DR CDD; cd05568; PTS_IIB_bgl_like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.1790.10; PRD domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR007737; Mga_HTH.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR013011; PTS_EIIB_2.
DR InterPro; IPR018356; Tscrpt_reg_HTH_DeoR_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR30185; CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR; 1.
DR PANTHER; PTHR30185:SF13; LICABCH OPERON REGULATOR-RELATED; 1.
DR Pfam; PF08279; HTH_11; 1.
DR Pfam; PF05043; Mga; 1.
DR Pfam; PF00874; PRD; 1.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 1.
DR PROSITE; PS00894; HTH_DEOR_1; 1.
DR PROSITE; PS51372; PRD_2; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
DR PROSITE; PS51099; PTS_EIIB_TYPE_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 288..395
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 401..490
FT /note="PTS EIIB type-2"
FT /evidence="ECO:0000259|PROSITE:PS51099"
FT DOMAIN 494..632
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
SQ SEQUENCE 636 AA; 72391 MW; AD1F7B01081BE68F CRC64;
MRFPNQRLAQ LFTLLRNETL PQDELAQRLS VSTRTVRADI TALNTLLAQY GAQFILNRGS
GYQLKIDNPT SFQALEETAP KAQHVPRTAQ DRITFLLVRF LTSAFSIKLE DLADEWFVSR
ATLQNDMVEV RERFQRYQLT LETRPRHGMK LFGSEVSIRA CLTDLLWELT QQGDIAPPIG
AEAFAAEVPA LLEPVLQETL TRHHIRLTDA GERFVCLYGA VVVRRVSEGY PLADFSAEDV
AQNVRDAARE LTGELQRLAG KPLSPAEEEW LCVHIAARQV QDVDPETISA DDDEALVNYI
LRYINSQYNY NLLDDAQLHA DLLTHIKTMI TRVRYQIMIP NPLLDNIKQH YPMAWDMTLA
AVSSWGKYTP YTISENEIGF LVLHIGVGLE RHYNIGYQRQ PQVLLVCDTS NAMVRMIEAI
LQRKYPQLEI AATISQREYE QRDAIEADFV ISTVRIGEKD KPVVTIAPFP TDYQLDQIGK
LVLVDRTRPW MLNKYFDAAH FRVVDKPMDQ QTLFAELCQQ LLEEGFVDAE FHASVVEREA
IVSTMLGDGI ALPHSLGLLA KKTVVYTVIA PQGIAWGDET AHLIFLLAIS KREYEEAMAI
YDIFVTFLRE RAMSRLAATR SFDEFKTVAM ECVSRF
//
