ID W9IZN6_FUSOX Unreviewed; 891 AA.
AC W9IZN6;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Alpha-actinin-like protein 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FOYG_02766 {ECO:0000313|EMBL:EWY98124.1};
OS Fusarium oxysporum NRRL 32931.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=660029 {ECO:0000313|EMBL:EWY98124.1, ECO:0000313|Proteomes:UP000030753};
RN [1] {ECO:0000313|EMBL:EWY98124.1, ECO:0000313|Proteomes:UP000030753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FOSC 3-a {ECO:0000313|Proteomes:UP000030753};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum FOSC 3-a.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the alpha-actinin family.
CC {ECO:0000256|ARBA:ARBA00010255}.
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DR EMBL; JH717840; EWY98124.1; -; Genomic_DNA.
DR AlphaFoldDB; W9IZN6; -.
DR HOGENOM; CLU_005217_0_1_1; -.
DR OrthoDB; 2872403at2759; -.
DR Proteomes; UP000030753; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd21215; CH_SpAIN1-like_rpt1; 1.
DR CDD; cd21291; CH_SpAIN1-like_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR014837; EF-hand_Ca_insen.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF08726; EFhand_Ca_insen; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM01184; efhand_Ca_insen; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 2.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000030753};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 247..352
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 361..467
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 721..756
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 859..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 891 AA; 101219 MW; 6473EEE519BDDBCE CRC64;
MDATKDSAQA FQGMLPLQPG NVEGNEKFPN FCLHADAQSS DDCDCNQQQR YQENKEHYYG
YQTDLSINNN SNQHHQHFHN SPSASISASS RLSYISTVSA SASSSSSRIS TASFESLPIT
PISVFEASPH SPRSLSNRLS SPVTGFIARR RTFTQDSCSL SYSPPSSPTP RTRRDKSQLH
AARVQRSGSR TTNTAFLLGL QIGKQSTNSR RFPPSASTPA DALAAVEPPH DQKLTRMAFA
EQQRWVTVQQ KTFTKWLNTK IEARNLEVKD LVKDLSDGVM LIHLLECLSH ESLGRYASKP
KLRVQKFENA NLALDFVKSR GIQMTNIGAE DVVDGNQKIV LGLIWTLILR FTISDINEEG
MSAKEGLLLW CQRKTACYDE VEVRDFSASW NDGLAFCALL DIHRPDLIDY DALDKKDHRG
NMQLAFDIAH KEIGIPKLLD VEDVCDVAKP DERSLMTYIA YWFHAFSQME KVENAGRRVE
KFVNNMQGAW EMQSAYERRM RALLQAIQEQ IEVWKQATFE GTYADAKAQS NQFFEYKKGK
KRQWVAEKSD LATLLGNIKT KLGTYRLRPY DPPAELSLDA LERKWAELAS NEMTRAQLIN
ETIRDIKNAL RKSFADKAND FAMALNTMQL AISGLDGDVE DQLHHVRKLS ESLSPLDQYL
DKISELDQKC QEANIEENDF TTYTYDELSY ELGLVKTSVQ KKLAFLENQM VARSMTNLTP
IQLEEFESVF RHFDRDDTNS LQELEFSAAL ASLGLVFSED EMHDYFLETS GGRDYVTFEQ
FIRFMVDVTE DQNTAEQVFQ SFREVADGKP YVTEMDLRHS LVPDEVIDQL IEIMPPHSGP
DMSEDRGMPQ YDYISFMEKL INDQNNQQED PEATQQNRSD AEPQSPHTNG V
//
