ID W9NSY4_FUSOX Unreviewed; 1049 AA.
AC W9NSY4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230};
GN ORFNames=FOVG_12981 {ECO:0000313|EMBL:EXA35858.1};
OS Fusarium oxysporum f. sp. pisi HDV247.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1080344 {ECO:0000313|EMBL:EXA35858.1};
RN [1] {ECO:0000313|EMBL:EXA35858.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HDV247 {ECO:0000313|EMBL:EXA35858.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum HDV247.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXA35858.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HDV247 {ECO:0000313|EMBL:EXA35858.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "Annotation of the Genome Sequence of Fusarium oxysporum HDV247.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; JH650977; EXA35858.1; -; Genomic_DNA.
DR AlphaFoldDB; W9NSY4; -.
DR HOGENOM; CLU_002346_0_0_1; -.
DR Proteomes; UP000030751; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR004199; B-gal_small/dom_5.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032312; LacZ_4.
DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR46323:SF1; LACTASE; 1.
DR Pfam; PF02929; Bgal_small_N; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF16353; LacZ_4; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SMART; SM01038; Bgal_small_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 763..1047
FT /note="Beta galactosidase small chain/"
FT /evidence="ECO:0000259|SMART:SM01038"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1049 AA; 118207 MW; 4D8ED0130C4522DC CRC64;
MGDSIQQEPK GIPLQEDPSR PDYINEAVFR RNTLPTRSYH IPDTSISLNG TWDFSLAGTV
LEAPEPGAKD VAYGQIQVPG HWQLQGHGKP WYTNVQYPIP VCPPYVPTEN PTGTYRREFH
VPTGWAADSQ LRLRFDGVDS AYHIWVNGTL IGYAQGSRNP SEFDVSSFVN REGANELFVR
VYQWSDATYI EDQDQWWLSG IFRDVYLISF PAARVDDFFL TPHLDTDYKN ARLNASVDVS
AQKGVIVELI VSELAKNGGA VIGSTETSFD GQSKVTLSLY VEDPKKWTAE TPYLYSAEIT
LKSEDKQTVL HKVQQRVGFR TVELKDGLMK VNGKRIRLRG VNRHEHHPLL GRSVPLEFAK
RDLLIMKKHN INALRCAHQP HDPRVLDLCD EYGLWVMAEA DLECHGFYDA VARPLDIPES
MDYGERKKLA FGKAAEFTSN NPKWKDAYLD RIRAVLNRDK NHASVIMWSF GNEAFYGDNH
REMFKYATEA DPSRLIHYEG DMEAETTHMY SYMYPTVDRL IKYAEEEGVK DGKYEKPIVL
CEYGHAMGNG PGWLEDYEQA FRDYPRLQGG FIWEWANHGL WKDDHEGAGY YAYGGDFGDT
PNDGTFVMDG LLNSQHDPTP GLTEFKKVIQ PVGFSFKDGE LKIENWHDFA GLDHLTASYK
VEQFGQESTL IHSGSFDIPE IPAGETRSVS LPVDAKRYNK DNEVYLTVTL SLKHSTAWAP
AGHEIAWYQQ QLQAPQTDAK AALAASNTLT SKLSVAEKGA TVSVFGKNFE FVFDRAYGAL
KSWVSNNVTL LTFDPKTQAA IIPSFWRPKT DNDVPGAVPY WERFGVEQLQ SQLRSFSVDA
SNSDKVVVKS HTFITPPVLF WGWDCEIEYT VYLTGALSVN VTRLSPTGSF PEHVPRIGLN
LYGSKTLEHV KWLGRGPGES YPDKKDSQRV GIWNAESVSE LQTPYDVPQE NGNREDTRWV
SLRDSKSPSI GLRATRLDGK NFSFLASHHR DTTIHEARHP PDLKEDGAVF IRLDSKVAGV
GSGACGPAVR EDLMVKTEET TFGFLLEPL
//
