ID W9RCM0_9ROSA Unreviewed; 260 AA.
AC W9RCM0;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=2-phytyl-1,4-beta-naphthoquinone methyltransferase, chloroplastic {ECO:0000256|HAMAP-Rule:MF_03192};
DE EC=2.1.1.329 {ECO:0000256|HAMAP-Rule:MF_03192};
DE AltName: Full=Demethylphylloquinone methyltransferase {ECO:0000256|HAMAP-Rule:MF_03192};
DE AltName: Full=Menaquinone biosynthesis methyltransferase ubiE-like protein {ECO:0000256|HAMAP-Rule:MF_03192};
GN Name=MENG {ECO:0000256|HAMAP-Rule:MF_03192};
GN ORFNames=L484_027734 {ECO:0000313|EMBL:EXB82557.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB82557.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the biosynthesis of phylloquinone (vitamin K1).
CC Methyltransferase required for the conversion of 2-phytyl-1,4-beta-
CC naphthoquinol to phylloquinol. {ECO:0000256|HAMAP-Rule:MF_03192}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=demethylphylloquinol + S-adenosyl-L-methionine = H(+) +
CC phylloquinol + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:40551,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:28433, ChEBI:CHEBI:57856,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:87844; EC=2.1.1.329;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_03192};
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000256|HAMAP-
CC Rule:MF_03192}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. MenG/UbiE family. {ECO:0000256|HAMAP-Rule:MF_03192}.
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DR EMBL; KE344869; EXB82557.1; -; Genomic_DNA.
DR RefSeq; XP_010100423.1; XM_010102121.1.
DR AlphaFoldDB; W9RCM0; -.
DR STRING; 981085.W9RCM0; -.
DR GeneID; 21410343; -.
DR KEGG; mnt:21410343; -.
DR eggNOG; KOG1540; Eukaryota.
DR OrthoDB; 46567at2759; -.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0052624; F:2-phytyl-1,4-naphthoquinone methyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0042372; P:phylloquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_01982; MenG_phylloquinone_subfam; 1.
DR HAMAP; MF_01813; MenG_UbiE_methyltr; 1.
DR InterPro; IPR032904; MenG.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004033; UbiE/COQ5_MeTrFase.
DR InterPro; IPR023576; UbiE/COQ5_MeTrFase_CS.
DR NCBIfam; TIGR01934; MenG_MenH_UbiE; 1.
DR PANTHER; PTHR43591; METHYLTRANSFERASE; 1.
DR PANTHER; PTHR43591:SF106; METHYLTRANSFERASE-LIKE PROTEIN 27; 1.
DR Pfam; PF01209; Ubie_methyltran; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51608; SAM_MT_UBIE; 1.
DR PROSITE; PS01183; UBIE_1; 1.
PE 3: Inferred from homology;
KW Chloroplast {ECO:0000256|HAMAP-Rule:MF_03192};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|HAMAP-
KW Rule:MF_03192}; Plastid {ECO:0000256|HAMAP-Rule:MF_03192};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691, ECO:0000256|HAMAP-
KW Rule:MF_03192};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW Rule:MF_03192}.
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 260 AA; 28847 MW; 30D21095424D928F CRC64;
MSTTHVLSLP LSSGSPTSRA RRSVLRPVRC SSERQALFNR IAPVYDNLND LLSLGQHRIW
KRMAVSWSGA KIGDCVLDLC CGSGDLAFLL SEKVGSDGNV TGLDFSKEQL SIAASRQQLL
SKKCYKNIEW VEGDALNLPF PNGYFDAITM GYGLRNVVDK RKALQEIYRV LKAGSRVSIL
DFNKSSQPVT TFIQDWMIDN VVVPVATSYG LQEEYIYLKS SIREFLTGKE LENLALEIGF
SKGRHYEIGG GLMGNLVAIR
//
