ID W9RGK5_9ROSA Unreviewed; 530 AA.
AC W9RGK5;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Diacylglycerol kinase {ECO:0000256|PIRNR:PIRNR030829, ECO:0000256|RuleBase:RU361128};
DE EC=2.7.1.107 {ECO:0000256|PIRNR:PIRNR030829, ECO:0000256|RuleBase:RU361128};
GN ORFNames=L484_018709 {ECO:0000313|EMBL:EXB89608.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB89608.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Phosphorylates the second messenger diacylglycerol (DAG) to
CC generate phosphatidic acid (PA), another important signaling molecule.
CC PA is required for plant development and responses to abiotic stress
CC and pathogen attack. {ECO:0000256|PIRNR:PIRNR030829}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-
CC phosphate + ADP + H(+); Xref=Rhea:RHEA:10272, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17815, ChEBI:CHEBI:30616, ChEBI:CHEBI:58608,
CC ChEBI:CHEBI:456216; EC=2.7.1.107;
CC Evidence={ECO:0000256|PIRNR:PIRNR030829,
CC ECO:0000256|RuleBase:RU361128};
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245,
CC ECO:0000256|PIRNR:PIRNR030829}.
CC -!- SIMILARITY: Belongs to the eukaryotic diacylglycerol kinase family.
CC {ECO:0000256|ARBA:ARBA00009280, ECO:0000256|PIRNR:PIRNR030829,
CC ECO:0000256|RuleBase:RU361128}.
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DR EMBL; KE345012; EXB89608.1; -; Genomic_DNA.
DR RefSeq; XP_010101753.1; XM_010103451.1.
DR AlphaFoldDB; W9RGK5; -.
DR STRING; 981085.W9RGK5; -.
DR GeneID; 21401675; -.
DR KEGG; mnt:21401675; -.
DR eggNOG; KOG1169; Eukaryota.
DR OrthoDB; 4642163at2759; -.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004143; F:ATP-dependent diacylglycerol kinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-UniRule.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007205; P:protein kinase C-activating G protein-coupled receptor signaling pathway; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR037607; DGK.
DR InterPro; IPR000756; Diacylglycerol_kin_accessory.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016961; Diacylglycerol_kinase_pln.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR11255; DIACYLGLYCEROL KINASE; 1.
DR PANTHER; PTHR11255:SF29; DIACYLGLYCEROL KINASE; 1.
DR Pfam; PF00609; DAGK_acc; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR PIRSF; PIRSF030829; Diacylglycerol_kinase_pln; 1.
DR SMART; SM00045; DAGKa; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR030829};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|PIRNR:PIRNR030829};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR030829};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821,
KW ECO:0000256|PIRNR:PIRNR030829};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Stress response {ECO:0000256|PIRNR:PIRNR030829};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR030829}.
FT DOMAIN 75..228
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
FT REGION 476..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..503
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 59372 MW; 9928231D9E293B0C CRC64;
MFRNRISPHT GNRLREFSSG SQTVARELRN FVQNFLSKSW ETIMSHMKSE NMLKDFYIPD
YLLLPGSEPP DARDIPECPV IVFINSKSGG QLGGELLVTY RSLLNKNQVF DLGENAPDKV
LHQLYANLGK LKHSGDAFAA EIEKRLRIIV AGGDGTAGWL LGVVSDLKLP QPPPIATVPL
GTGNNLPFSF GWGKKNPGTD QQSVETFLYQ VRAAKEMKID SWHIIMRMRA PKEGSCEPIA
PLELPHSLHA FHRVSQTDAL NVEGYHTYRG GFWNYFSMGM DAQVSYAFHS ERKLHPEKYK
NQLVNQSTYL KLGCTQGWFC ASLLHPASKN IAQLTKIMVM KKQGQWEELS IPHSIRSIVC
LNLPSFSGGL NPWGKPHGRK LRDRDLTPPY VDDGLLEIVG FRNGWHGLVL LAPKGHGTRL
AQASGVRFEF QKGAANHTFM RIDGEPWKQP LPNDDDTVVV EITHFGQVSM LARPSCRSKS
VYDPSSPASY GDEDEDSFED DSTEDSEERR KFGAADTFKF PEGFDIAHLS
//
