ID W9V808_9GAMM Unreviewed; 321 AA.
AC W9V808;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=D779_1101 {ECO:0000313|EMBL:EXJ15713.1};
OS Imhoffiella purpurea.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Imhoffiella.
OX NCBI_TaxID=1249627 {ECO:0000313|EMBL:EXJ15713.1, ECO:0000313|Proteomes:UP000019460};
RN [1] {ECO:0000313|EMBL:EXJ15713.1, ECO:0000313|Proteomes:UP000019460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK35 {ECO:0000313|EMBL:EXJ15713.1,
RC ECO:0000313|Proteomes:UP000019460};
RA Nupur N., Khatri I., Subramanian S., Pinnaka A.;
RT "Genome assembly of Thiorhodococcus sp. AK35.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ15713.1}.
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DR EMBL; AONC01000022; EXJ15713.1; -; Genomic_DNA.
DR RefSeq; WP_043751949.1; NZ_AONC01000022.1.
DR AlphaFoldDB; W9V808; -.
DR STRING; 1249627.D779_1101; -.
DR PATRIC; fig|1249627.3.peg.1552; -.
DR eggNOG; COG2367; Bacteria.
DR OrthoDB; 7054239at2; -.
DR Proteomes; UP000019460; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Reference proteome {ECO:0000313|Proteomes:UP000019460}.
FT DOMAIN 131..274
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 321 AA; 36593 MW; F847E6CA40671039 CRC64;
MRFFASMERA AEDVAARSRH PDDPERRWFL EALLASSAGA LIGIPDLAEA KSVDSPLERQ
VSRLVKKMRR QGRISASERT SWSVYDFTTR TKLVSINEAV PRQAASMIKP FVAQAYFYQV
DQGRKGARYT SSVRHTMERM IQHSDNRATN RIIDLVSRHG AGRGPREVEA VLKAAAPNVF
KQVRVVEKIP DSGATYANRA SAWDYSRFLY AMHHGKLPYS EEMRRLMRLP NHDRIFKGVP
GIPSSVHVCD KTGSTAKLCG DMGILEARDR HGRYHAYTMI GIIERQTRAR NYGSWISKRS
DAIREVSNLV YQYMKDRHHL V
//
