ID   W9WLT7_9EURO            Unreviewed;       685 AA.
AC   W9WLT7;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Serine palmitoyltransferase {ECO:0000313|EMBL:EXJ65960.1};
GN   ORFNames=A1O5_10936 {ECO:0000313|EMBL:EXJ65960.1};
OS   Cladophialophora psammophila CBS 110553.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ65960.1, ECO:0000313|Proteomes:UP000019471};
RN   [1] {ECO:0000313|EMBL:EXJ65960.1, ECO:0000313|Proteomes:UP000019471}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ65960.1,
RC   ECO:0000313|Proteomes:UP000019471};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXJ65960.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AMGX01000022; EXJ65960.1; -; Genomic_DNA.
DR   RefSeq; XP_007749700.1; XM_007751510.1.
DR   AlphaFoldDB; W9WLT7; -.
DR   STRING; 1182543.W9WLT7; -.
DR   GeneID; 19195627; -.
DR   eggNOG; KOG1357; Eukaryota.
DR   HOGENOM; CLU_015846_7_2_1; -.
DR   OrthoDB; 9643at2759; -.
DR   Proteomes; UP000019471; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd06454; KBL_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR13693; CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE; 1.
DR   PANTHER; PTHR13693:SF3; LD36009P; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019471};
KW   Transferase {ECO:0000313|EMBL:EXJ65960.1}.
FT   DOMAIN          255..612
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   685 AA;  75041 MW;  9A3B0DC091EF978E CRC64;
     MPRRVSSSLL SSSPPTPWPS FSPSEKGGSL VNKTSQKASK IAQFFSTSPK TKEAQSAAAA
     LLAASKAQEQ AFLASGSPPI STPSLSLPSI SLSTAQADSA NMDEPPTTLF QPPSPAETRK
     LARQHAQFGP LNSQSHRYTS RHQGGEFPEP VMDEPPYYYL LTTYISYLIL IIFGHVRDFF
     GMKLKEDNYR HLKARNGYAA LNNDFDNFYV RRLKMRINDC FNRPTTGVPG RFINLLDRTS
     DDGNVHFTMT GTTTETLNMS SYNYLGFAQS EGPCADSVEE TIRRCGLSTA SPRSEVGTSE
     LAVECETLIA DFVGKESAMV FSMGFGTNAS IFPALVGKGD LIISDELNHA SIRFGSRLSG
     AMISSFKHND MKDLEGRLRE AISQGQPRTH RPWKKILVVV EGLYSMEGTM CNLPGLVRLK
     KRYKFNLFVD EAHSVGALGP RGRGVCDYFG IDPSEVDILM GTLTKSFGAN GGYVAGEKAA
     IDKLRLSNAG TVYGETPSPA VLAQIIAALR IINGELVPGQ GEERLQRIAF NSRYLRLGLK
     RLGFIVYGHD DSPIIPLMLY NPAKMPAFSH EMLKRKISVV VVGYPATPLI SSRARFCVSA
     AHNKDDLDRL LAACDEIGNV LQLKFASGIA GGAPPLPEGV TWEMEQSRKR LEKHDKVAKS
     LVVSPRWSLD EVIKRGVQDV KVPLR
//