ID   W9WP27_9EURO            Unreviewed;      1346 AA.
AC   W9WP27;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=5-oxoprolinase (ATP-hydrolysing) {ECO:0000313|EMBL:EXJ60174.1};
GN   ORFNames=A1O7_04326 {ECO:0000313|EMBL:EXJ60174.1};
OS   Cladophialophora yegresii CBS 114405.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ60174.1, ECO:0000313|Proteomes:UP000019473};
RN   [1] {ECO:0000313|EMBL:EXJ60174.1, ECO:0000313|Proteomes:UP000019473}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ60174.1,
RC   ECO:0000313|Proteomes:UP000019473};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXJ60174.1}.
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DR   EMBL; AMGW01000003; EXJ60174.1; -; Genomic_DNA.
DR   RefSeq; XP_007756527.1; XM_007758337.1.
DR   STRING; 1182544.W9WP27; -.
DR   GeneID; 19178912; -.
DR   VEuPathDB; FungiDB:A1O7_04326; -.
DR   eggNOG; KOG1939; Eukaryota.
DR   HOGENOM; CLU_002157_0_1_1; -.
DR   OrthoDB; 674at2759; -.
DR   Proteomes; UP000019473; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019473}.
FT   DOMAIN          12..233
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          253..558
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          573..750
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          774..1314
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
SQ   SEQUENCE   1346 AA;  147373 MW;  491EFA2FB17D7CDE CRC64;
     MGDAGRGEGG IRIAIDRGGT FTDCVGNPGT GRMEDDIVIK LLSEDPSNYE DAPLEGIRRL
     MSKFTRREIP RGEPLDTSKI ESIRMGTTVA TNALLERKGE KMAMVVTRGF KDCLEIGNQS
     RPKIFDLAIR RPDVLYQKVV EVDERVTLED YAEDPERHQT KAEAKHEDFK NHDLVEGLSG
     EAVRILRRPE EGKIKEQLKQ LYEEGFRSIA VCLMHGYTFP DHEALVGKLA HEIGFQHVSL
     SHALMPMIKL VPRATSACAD AYLTPAIKKY IAGFQAGFEG GLGTESVKKE EGEKGARCEF
     MQSDGGLVDV DQFSGLRAIL SGPAGGVVGY ALTSYDRETK TPVIGFDMGG TSTDVSRYGQ
     GRYEHVFETT TAGVTIQSPQ LDINTVAAGG GSRLFFRNGL FVVGPESAGA HPGPACYRKG
     GPLTVTDANL FLGRLLPEFF PKIFGKNEDE GLDPEASRKL FEELTNEINS QTDTHMTADE
     VAYGFIKIAN ETMTRPIRSL TEAKGHDTSQ HRLATFGGAG GQHAVAIAES LGIRQILVHR
     YSSVLSAYGM ALADVVDESQ VPESHVWDDS SSHDDLKKKM AELKERSRTR LNDQGFADDA
     IEFEEYLNMR YRGTESALMV IKPTQSESEE LYDGDDWAFG AAFVRQHEQE FGFTLPDRDT
     IVDDVRVRGI GKSFRGMSKT ADQQLKEIKP QDVAPEKAHS TAKVYFEGGR QDTRIYKLED
     LEVGSRVAGP AIIADGTQTI VVTPGASALV IETHVMINIG EEGTSKKANA EEVDPILLSI
     FAHRFMAIAE QMGRALQKTS VSTNVKERLD YSCALFDEQG GLVANAPHLP VHLGSMSTCV
     RTQAEIWRGK LKKGDVVVSN HPEYGGTHLP DITVVTPAFS GDKIIFYVAS RAHHADIGGI
     LPGSMPPHSR ELYQEGAAIK SEKLVSEGKF DEKKITELLY DEPAQYPDCS GTRCLADNLN
     DLKAQIAANQ KGINLISALI EDYGEDVVQF YMQNIQNNAE KSVRELLKEV SKRFEGKDLQ
     AVDYMDDGSP IALKISIDAE KGEAVFDFEG TGPEVYGNIN APEAVTYSAI IYCLRCLIDQ
     DIPLNQGCLK PVDVRIPPGS FLSPSEKAAV VGGNVLTSQR VTDVVFKCFE ACAASQGDCN
     NLTFGFGGNL KGGTETKGFG YYETIAGGSG AGKDWEGTSG VHTHMTNTRI TDAEVFERRY
     PVILREFSLR AGSGGVGQHR GGDGVVRDIE FRIPVQVSIL SERRVYRPYG LHGGGDAQCG
     KNIWVRKVKK RRDDGGEEEY EKRFISMGAK NTASMQPGER IIVMTPGGGG YGKPGEKSQV
     DLKEDFEKHW KKGSLASRLA EWESSS
//