ID W9X0Q3_9EURO Unreviewed; 718 AA.
AC W9X0Q3;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Anaphase-promoting complex subunit 2 {ECO:0000256|ARBA:ARBA00016068};
GN ORFNames=A1O7_00415 {ECO:0000313|EMBL:EXJ64079.1};
OS Cladophialophora yegresii CBS 114405.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ64079.1, ECO:0000313|Proteomes:UP000019473};
RN [1] {ECO:0000313|EMBL:EXJ64079.1, ECO:0000313|Proteomes:UP000019473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ64079.1,
RC ECO:0000313|Proteomes:UP000019473};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ64079.1}.
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DR EMBL; AMGW01000001; EXJ64079.1; -; Genomic_DNA.
DR RefSeq; XP_007752646.1; XM_007754456.1.
DR AlphaFoldDB; W9X0Q3; -.
DR STRING; 1182544.W9X0Q3; -.
DR GeneID; 19175031; -.
DR VEuPathDB; FungiDB:A1O7_00415; -.
DR eggNOG; KOG2165; Eukaryota.
DR HOGENOM; CLU_007149_0_1_1; -.
DR OrthoDB; 2786196at2759; -.
DR Proteomes; UP000019473; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044554; APC2-like.
DR InterPro; IPR014786; APC2_C.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45957; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR45957:SF1; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR Pfam; PF08672; ANAPC2; 1.
DR Pfam; PF00888; Cullin; 1.
DR SMART; SM01013; APC2; 1.
DR SMART; SM00182; CULLIN; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000019473};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 380..575
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 718 AA; 80661 MW; 9798FC93F6CACB23 CRC64;
MQTLPPTLPT DGVFASVFPS GIQPPKHRRR FAPKAAALIP DIQRTLKDQL RLLLGIGNES
FVYGHSRMVT NAGAPFHSHF GSSGIEYRIR EPTAVDHAKH ITRENSSPLW SMLSQWRSAV
GSETVMKLLA TVLNELMTEF VTWSYAGIYQ EGLYHHLEFW IQHLFSRIAY KVLGCLDDSF
NAQRVPETEI KKWKDMAVAR LGALRVDELF EIIVDWDATA PAIEDLRQFT TNPATRGYLT
HDFANVLQTR LLHPGASTIE ILQLYIAITR SFRVLDPKGV LLDRVARRVR RYLRERDDTV
KVIVTGLLAD TAPQENGREP SSDPEVLSEL ALELHRHNAR DNTTEDSEFD WNNMEWLPDP
VDAAPDYMKS NKNTDVIGSL ITLFDTKDVF VKELQSTLAE RLLKNKPDFN QEISVLEHLK
IRFGDSALQA CEVMLRDVLD SRKVDHVIRR DLEKEGTSGR MDEEDGGIEL HAKILSRLFW
PSMLEQSFTV PPEILERQES YEKGFGALKQ SRKLTWLNAI GQVDVELELE DRSLREEVLP
WQAAVIHAFQ DKAAQGEDQP VSKSVSQLAT ELEMSPTLAR SACIFWVSKR ILHEISANTF
IVLESLPSGT EFDTNMTNDS STETQASTAA AAEAAALAAA KEAEEAERKQ KMAMYHQFVV
SMLTNQGSMP LARIAMMLGI VVPGGFPFSN EELKEFLAGM VKEGVLEVGN AGVYKIAS
//
