ID W9XL02_9EURO Unreviewed; 2034 AA.
AC W9XL02;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 08-NOV-2023, entry version 41.
DE RecName: Full=Activating signal cointegrator 1 complex subunit 3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A1O3_07139 {ECO:0000313|EMBL:EXJ80853.1};
OS Capronia epimyces CBS 606.96.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX NCBI_TaxID=1182542 {ECO:0000313|EMBL:EXJ80853.1, ECO:0000313|Proteomes:UP000019478};
RN [1] {ECO:0000313|EMBL:EXJ80853.1, ECO:0000313|Proteomes:UP000019478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 606.96 {ECO:0000313|EMBL:EXJ80853.1,
RC ECO:0000313|Proteomes:UP000019478};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia epimyces CBS 606.96.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ80853.1}.
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DR EMBL; AMGY01000006; EXJ80853.1; -; Genomic_DNA.
DR RefSeq; XP_007735441.1; XM_007737251.1.
DR STRING; 1182542.W9XL02; -.
DR GeneID; 19171241; -.
DR eggNOG; KOG0952; Eukaryota.
DR HOGENOM; CLU_000335_2_0_1; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000019478; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0010467; P:gene expression; IEA:UniProt.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd18020; DEXHc_ASCC3_1; 1.
DR CDD; cd18022; DEXHc_ASCC3_2; 1.
DR CDD; cd18795; SF2_C_Ski2; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF13; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 2.
DR PIRSF; PIRSF039073; BRR2; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019478}.
FT DOMAIN 291..484
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 520..719
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1167..1343
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1377..1572
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 2034 AA; 228790 MW; FC91222992CDFC8A CRC64;
MVETAFQSEA QWLSQMAAMR EAIAELKLPP FNDASQLYGA DLDLDQELSD DIDDDIWDVE
SSLAESPPSD IFDETANGFK IPDAVDGVFD SSWLRSRCDA FARARSGLDA SDLEQQIIAL
LASDSSDDEL QMSLAEIVGY DALDFVIELI SHRRAILTAP TSSTRQTDGL FGQLETRQQR
EASLRRQDHE HKHTSLAPAY DRSERKYPHV YKSDTAASGN MLDVSGKRYG LPMGSTRNDY
PKYEEFSIPA SKVGSLAAGQ KLVNIAEMDA LCQRTFKGYK SLNRMQSLLY QVAYTTSENM
LICAPTGAGK TDAAMLTILQ AISKNVVPNP LEEPTATDFT VMADDFKIVY VAPMKALAAE
VTEKLGKRLA WLGIQVRELT GDMQLTKREI AATQIIVTTP EKWDVVTRKS TGDTELVQKV
RLLIIDEVHM LHDDRGAVIE SLVARTERQV ESTQSMIRIV GLSATLPNYV DVAKFLKVNL
NAGLFYFDAS FRPVPLEQHF IGVKGKVGSK TQRENLDHVT FEKIKEVLKQ DKQIMVFVHS
RKDTVLTART LYSMAVDDGC VELFVPSPDS PAYSKAMTDL KMTRGRELRD IVPKGFGCHN
AGMARTDRNF VERIFSDGAI RVLCCTATLA WGVNLPAAAV IIKGTQIYSA EAGKFVDLGI
LDVLQIFGRA GRPQFQDSGI GYICTTQDKL QHYLSAVTQQ RPIESRFSQK LVDNLNAEIS
LGTVTSVQEG VTWLGYSYLF VRMRQKPEAY GIDWNEYQDD PQLFQRRRKL IVDAARILHR
SQMIIFNERT DELRAKDVGR IASQFYVLQN SIEIFNTMMR PHASEADVLK MISMSGEFDN
IQSRENEAQE LHRLRQEAVA CEVEERRDTP QSSKDEKEKR VIENHAKTNI LLQSHISRAK
LEDFALASDL AYVAQNSARI CRALFMIALN RGWGYQCQVL LSMCKAIEKQ IWPFQHPFHQ
FDLPLSVLKN LDEKAPSSNI ESLREMEPAE IGNLVHNHKM GNTISKLLDN FPTLSVEAEI
APLNRDVLRM RLYLYPEFVW NDRHHGTSES YWVWVENSET AEIYHHEYFI LSRRKMHDDH
ELNFTIPLAD PLPSQIYVRV ISDRWLGAET VQPVSFQHLI RPDTESVYTD LLDLQPLPIT
ALKNPQLEEL YGQRFQFFNP MQTQIFHTLY NTSNNVLLGS PTGSGKTVAA ELAMWWAFRE
NPGSKVVYIA PMKALVRERV QDWRKRLALP LGLKLVELTG DNTPDTRTIR DADIIITTPE
KWDGISRSWQ TRSYVRQVSL VIIDEIHLLG GDRGPILEII VSRMNYIATQ AETGSIRLVG
MSTACANATD LANWLGVKPG NNQGLFNFRH SVRPVPLEIY IDGFPEQRGF CPLMQSMNRP
TYLAIKNHSP DKPVIVFVAS RRQTRLTAKD LINYCGMEED PRRFLHFDSE DDFQHTLAAV
KDAALKEALS FGIGLHHAGL VESDRTLAEQ LFAANKIQIL VATSTLAWGV NLPAHLVVVK
GTQYFDAKIE GYKDMDLTDV LQMLGRAGRP QFDTSGIARI FTQDSKKAFY KHFLHTGFPV
ESSLHKVLDN HLGAEVSAGV ITTKQDALDY LTWTFFFRRL HKNPTYYGLE ISEEEHKDNQ
TLARQQAADY MVSMVDKSLD DLAESDCVLV HSNGDVDSTP FGKIMSYYYL SHLTIRTFLS
RARKVPSTTF ADALAWISLA TEFDDLPVRH NEDLINAELA KNLPLDTLGL LDGLPMWDPH
VKAFLLIQAF MSRVELPISD YVGDQISVLD QGIRIIQAGI DVMTELNKFD AVVQMIRLLQ
CIKSARWPED YPLSILPGVS EILDPKLDGK VPKDLNTTAV LASRHGTKTI EGLMNTLGIR
IPNVRAQFGK AANALPDITL TSNGNTELLQ LTMKRGNRLL DAEARIYAPK FPKPQTEGYL
ALVLPTGRQG DILALKRANW ATMKNKQGAR QNRAVEVSNI KLKIPVSEAA TYDGRSSTIG
GEVEVNIVVM SDAYPGMEWR LDRVKVPIAK PESVETVEVG VDESLQKKNQ QQQG
//
