ID   X0BNX6_FUSOX            Unreviewed;       570 AA.
AC   X0BNX6;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Phytoene desaturase {ECO:0000256|ARBA:ARBA00013293};
DE   AltName: Full=Phytoene desaturase (3,4-didehydrolycopene-forming) {ECO:0000256|ARBA:ARBA00034551};
GN   ORFNames=FOQG_11839 {ECO:0000313|EMBL:EXK83885.1};
OS   Fusarium oxysporum f. sp. raphani 54005.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=1089458 {ECO:0000313|EMBL:EXK83885.1, ECO:0000313|Proteomes:UP000030663};
RN   [1] {ECO:0000313|EMBL:EXK83885.1, ECO:0000313|Proteomes:UP000030663}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=54005 {ECO:0000313|EMBL:EXK83885.1,
RC   ECO:0000313|Proteomes:UP000030663};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Fusarium oxysporum PHW815.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC         Evidence={ECO:0000256|ARBA:ARBA00001911};
CC   -!- PATHWAY: Carotenoid biosynthesis. {ECO:0000256|ARBA:ARBA00004829,
CC       ECO:0000256|RuleBase:RU362075}.
CC   -!- SIMILARITY: Belongs to the carotenoid/retinoid oxidoreductase family.
CC       {ECO:0000256|ARBA:ARBA00006046, ECO:0000256|RuleBase:RU362075}.
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DR   EMBL; KI979327; EXK83885.1; -; Genomic_DNA.
DR   AlphaFoldDB; X0BNX6; -.
DR   eggNOG; KOG4254; Eukaryota.
DR   HOGENOM; CLU_019722_2_1_1; -.
DR   Proteomes; UP000030663; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR   GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR014105; Carotenoid/retinoid_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR008150; Phytoene_DH_bac_CS.
DR   NCBIfam; TIGR02734; crtI_fam; 1.
DR   PANTHER; PTHR43734; PHYTOENE DESATURASE; 1.
DR   PANTHER; PTHR43734:SF1; PHYTOENE DESATURASE; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS00982; PHYTOENE_DH; 1.
PE   3: Inferred from homology;
KW   Carotenoid biosynthesis {ECO:0000256|ARBA:ARBA00022746,
KW   ECO:0000256|RuleBase:RU362075}; Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU362075};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030663};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        547..567
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          16..381
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
SQ   SEQUENCE   570 AA;  62664 MW;  F05560D96BF1BFE6 CRC64;
     MSGIKKSVII IGAGVGGVST AARLAKAGFK VTILEKNDFT GGRCSLIHND GHRFDQGPSL
     LLLPRFFHEI FQDLGTSLTA EGVELLKCEP NYNIWFGDGS SFEMSTDLTK MKKAIEAVEG
     IDGFERYLGF LQESHRHYEV SVESVLRRNF PSILSLARPE VLFNLFNIHP LESIWTRASK
     YFWTERLRRV FTFGSMYMGM SPFDAPGTYS LLQYTELAEG ILYPRGGFHK VVEALVNVGQ
     RLGVEYRLST GVKSISIDQA TGKANGVVLS DGTHLPSDIV ISNADLVYTY NNLLPKTSYA
     DSLSKRETSC SSISFYWSAS KIIPELNAHN IFLADEYQES FDSIFKEHLI PSEPSFYVNV
     PSRIDPSAAP EGKDSIVVLV PVGHLLSDSE GTHRGLSKSG NSGGLETSQD WDKMISLARD
     TVIATMRARI GVDLAPLIEN EIINTPFTWQ EKFNLDKGAI LGLSHSIMNV LAFRPGTQHS
     KYKNLYFAGA STHPGTGVPV CIAGSKIVAE QILKDSGFKN HQIPWAQDTA KSPKGGLDKM
     SDSSLTLFQG FLGALVAILL AYYYLVIAAN
//