ID   X1KEX3_9ZZZZ            Unreviewed;       345 AA.
AC   X1KEX3;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Alcohol dehydrogenase N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=S06H3_00258 {ECO:0000313|EMBL:GAH92185.1};
OS   marine sediment metagenome.
OC   unclassified sequences; metagenomes; ecological metagenomes.
OX   NCBI_TaxID=412755 {ECO:0000313|EMBL:GAH92185.1};
RN   [1] {ECO:0000313|EMBL:GAH92185.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Expedition CK06-06 {ECO:0000313|EMBL:GAH92185.1};
RX   PubMed=24624126; DOI=10.3389/fmicb.2014.00080;
RA   Kawai M., Futagami T., Toyoda A., Takaki Y., Nishi S., Hori S., Arai W.,
RA   Tsubouchi T., Morono Y., Uchiyama I., Ito T., Fujiyama A., Inagaki F.,
RA   Takami H.;
RT   "High frequency of phylogenetically diverse reductive dehalogenase-
RT   homologous genes in deep subseafloor sedimentary metagenomes.";
RL   Front. Microbiol. 5:80-80(2014).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAH92185.1}.
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DR   EMBL; BARV01000040; GAH92185.1; -; Genomic_DNA.
DR   CDD; cd08282; PFDH_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42813:SF3; GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          15..114
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          165..265
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
FT   NON_TER         345
FT                   /evidence="ECO:0000313|EMBL:GAH92185.1"
SQ   SEQUENCE   345 AA;  37165 MW;  60AE05587BD65874 CRC64;
     MRVEWVSESA WNPHNICGSD LHMYEGRTSF EAGRVFGHEN LGEVIEVGAG VDRVKVGDRV
     CLPFNIGCGF CENCEKGLTG FCLTANPGAA GAAYGFAEMG PYQGGQAELL RVPYADFNCL
     VLPEDAQERE DDYVMLSDIF PTGWHATELA GLLPGESIAI YGAGPVGLMA AHSAIIKGAS
     QVFVIDNQPD RLQLAAQLGA TPINAVEQKA VEEIMNLTHG KGTDRGCECV GYQCCDKHGH
     EANYLTMNNL VASTKATGGI GVVGVFVPED PGAKNELAKQ GKMAFDFGAF WFKGQQIRTG
     QANVKAYNRR LAELIHHGRA KPSQIISHRL KLAEGPDAYK HXDAR
//