ID X1W3S0_TETTS Unreviewed; 463 AA.
AC X1W3S0;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=RING-H2 zinc finger protein {ECO:0000313|EMBL:EDK31570.1};
GN ORFNames=TTHERM_00131298 {ECO:0000313|EMBL:EDK31570.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EDK31570.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662639; EDK31570.1; -; Genomic_DNA.
DR RefSeq; XP_001470884.1; XM_001470834.2.
DR AlphaFoldDB; X1W3S0; -.
DR STRING; 312017.X1W3S0; -.
DR GeneID; 24442145; -.
DR KEGG; tet:TTHERM_00131298; -.
DR InParanoid; X1W3S0; -.
DR OrthoDB; 53998at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46225; C3H4 TYPE ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR46225:SF19; RING-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 320..363
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 26..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 463 AA; 54780 MW; 50827253591B8BE5 CRC64;
MNEPLLAGVA PLPMNQPNMI NQNSVAEQQD QNQQNNNNNQ NENENEDVEQ GRGNSQRNSV
QSFIRDSLRL SQRQQNRINV RNNFRGQIEE AINESIVINA LFLFISVNKM IAYIVLGKNS
SQETCKDGQL CIWLKLMFLH DALYSIHLIT LLVVIFIHRH RGIMSRWQNM EGMENDYQQM
QDANNQVQPN FNGFYVTEFI TKKNWFNSFL QDSTKLFYLI IFIQGNLLIF YNEEQYLSSY
PNHFYLALVY VIMGYFYLGI PLFFFASICL CMPFMLVIYL VLRRRRNGIQ RGLDEDAINS
LPIKYLKDVE RKEEDDTLEC CICLVEYEEE EEIIILPCNK NHHFHAKCIK QWVKINGVCP
ICKRDLKELL IRLNDVHDEN QQEEMQEIHQ NQNIQQQQHA QNNNDIHNNN NNNHNNHNHD
NNNIQQNIIN QNNQDDNHQN SNNNNNSHHH HNIENQYQPP FRM
//
