ID X2AMG5_CAPTE Unreviewed; 768 AA.
AC X2AMG5;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EnsemblMetazoa:CapteP217617, ECO:0000313|Proteomes:UP000014760};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP217617}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; AMQN01007814; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; X2AMG5; -.
DR EnsemblMetazoa; CapteT217617; CapteP217617; CapteG217617.
DR HOGENOM; CLU_004747_7_1_1; -.
DR OMA; MFKDMTI; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 379..636
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 677..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 768 AA; 88631 MW; 141DAEABE4C0DE91 CRC64;
MSGLKGKKDT KMRIRAFPVT MDEKYVNNIW TLLKNAIQEI QKKNNSGLSF EELYRNAYTM
VLHKHGEKLY TGLREVVIDH LVNKVQSDVL ESLNNNFLQT LNNSWNDHQT SMVMIRDILM
YMDRVYVQQN SVDNVYNLGL MIFRDKVVRY PVIRSHLRDT LLDMVAKERR GEVVDRGAVK
NACQMLMILG IDSRTVYEED FERPFLEQSA DFYKMESQRF LAENSASVYI KKVEARIHEE
AERATHYLDK STEDPIVKVL EDELICKHMK TIVEVEYSGV VHMLKNNKTE GLECMYKLFI
RVVEGLKTMC GCISGYLREQ GKALVTEEEG GKNAISFVQG LLDLKDRFDH FLHQSFSDDR
QFKQMISSDF EYFININPKS PEYLSLFIDD KLRKGVKGVT EQEIEAVLDK SMVLFRFLQE
KDVFERYYKQ HLAKRLLLNK SVSDDSEKNM ISKLKAECGC QFTSKLEGMF KDMTVSNTTM
EEFKSHVQNA TVNLHGVDLL VRVLTTGFWP FQSASSKCNV PLAPRMAFEA FKKFYLGKHS
GRQLSLQPQH GSADLNAIFY GARKGESGAE GGAASEEGAS CSSASSRARK HIIQVSTYQM
VILMLFNNRD HWTYEEMKNE SDIPERDLMR AVQSLALGKH TQRVLMKEPK SKEIEGSHVF
MVNEQFTSKL HRVKIQTGAA KGESEPERKE TRNKVEEDRK HEIEAAIVRI MKARKQMKHN
VLVAEVTEQL KARFLPSPVV IKKRIEGLIE RDYLARTPED RKIYTYVA
//
