ID X2J2Q0_SALSA Unreviewed; 405 AA.
AC X2J2Q0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=CRFB5a {ECO:0000313|EMBL:AHN52533.1};
DE SubName: Full=CRFB5b {ECO:0000313|EMBL:AIN50148.1};
DE SubName: Full=Interferon Alpha/beta receptor 1A {ECO:0000313|RefSeq:XP_014030076.1};
GN Name=CRFB5a {ECO:0000313|EMBL:AHN52533.1};
GN Synonyms=LOC106586873 {ECO:0000313|RefSeq:XP_014030076.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:AHN52533.1};
RN [1] {ECO:0000313|EMBL:AHN52533.1}
RP NUCLEOTIDE SEQUENCE.
RA Sun B., Greiner-Tollersrud L., Koop B., Robertsen B.;
RT "Identification of Atlantic salmon interferon receptor genes.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AIN50148.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25149134; DOI=10.1016/j.dci.2014.08.007;
RA Sun B., Greiner-Tollersrud L., Koop B.F., Robertsen B.;
RT "Atlantic salmon possesses two clusters of type I interferon receptor genes
RT on different chromosomes, which allows for a larger repertoire of
RT interferon receptors than in zebrafish and mammals.";
RL Dev. Comp. Immunol. 47:275-286(2014).
RN [3] {ECO:0000313|RefSeq:XP_014030076.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KF976460; AHN52533.1; -; mRNA.
DR EMBL; KF845942; AIN50148.1; -; Genomic_DNA.
DR RefSeq; NP_001306948.1; NM_001320019.1.
DR RefSeq; XP_014030076.1; XM_014174601.1.
DR GeneID; 106586873; -.
DR KEGG; sasa:106586873; -.
DR OrthoDB; 5320327at2759; -.
DR Proteomes; UP000087266; Chromosome ssa25.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR PANTHER; PTHR20859:SF50; INTERLEUKIN-10 RECEPTOR SUBUNIT BETA; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_014030076.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..405
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010851826"
FT TRANSMEM 234..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 126..228
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 325..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 46061 MW; CF34FD48911397A3 CRC64;
MNVGFALVLL WSLPITSVLA ELPQPQNLTL LTLNTQYVLT WDWDQTATGN AVTFTVEYMA
KYKMMKKKKN WSRVCERTTH TRCDLTDSDL HYLGMYVVRV QASADGVNSH WVYKDFCPDM
DASLGPPSRV ELAPVGNLLD VTISDPLTST QGSMKEHVLF LYYRILYWSL SDDPQGLKPK
VVDSSNNLVT LPELEAWTWY CVMIQSRYDY YNKTSGYTEP QCMQTEGDTP YGQIFLYFLV
SMVVCFLLVL LPSYTFFRFY RVLKNTFYPS IQLPAHIQEY LCDSSPGSDM PRLLTADSEA
ELCCDKLTIC PEVVLLEIHL PPPLTAPPSE LEQDSGRHIR QDSGDSGIYS TEGGSAQQGR
SGGEPIRRDQ EVDSWQTLEQ VKMDEMWRES ADERDLDEGV VDVCV
//
