ID X5DA24_9BACT Unreviewed; 117 AA.
AC X5DA24;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Dihydroneopterin triphosphate 2'-epimerase {ECO:0000256|ARBA:ARBA00044197};
DE EC=5.1.99.7 {ECO:0000256|ARBA:ARBA00044039};
DE AltName: Full=D-erythro-7,8-dihydroneopterin triphosphate epimerase {ECO:0000256|ARBA:ARBA00044306};
GN ORFNames=SAMN05444285_102149 {ECO:0000313|EMBL:SES81194.1};
OS Draconibacterium orientale.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Prolixibacteraceae;
OC Draconibacterium.
OX NCBI_TaxID=1168034 {ECO:0000313|EMBL:SES81194.1, ECO:0000313|Proteomes:UP000181981};
RN [1] {ECO:0000313|EMBL:SES81194.1, ECO:0000313|Proteomes:UP000181981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25947 {ECO:0000313|EMBL:SES81194.1,
RC ECO:0000313|Proteomes:UP000181981};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=7,8-dihydroneopterin 3'-triphosphate = 7,8-dihydromonapterin
CC 3'-triphosphate; Xref=Rhea:RHEA:28346, ChEBI:CHEBI:58462,
CC ChEBI:CHEBI:61186; EC=5.1.99.7;
CC Evidence={ECO:0000256|ARBA:ARBA00043806};
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DR EMBL; FOHT01000002; SES81194.1; -; Genomic_DNA.
DR RefSeq; WP_038557512.1; NZ_FOHT01000002.1.
DR AlphaFoldDB; X5DA24; -.
DR STRING; 1168034.FH5T_08700; -.
DR GeneID; 78098354; -.
DR eggNOG; COG1539; Bacteria.
DR HOGENOM; CLU_112632_0_0_10; -.
DR OrthoDB; 1121389at2; -.
DR Proteomes; UP000181981; Unassembled WGS sequence.
DR GO; GO:0004150; F:dihydroneopterin aldolase activity; IEA:InterPro.
DR GO; GO:0006760; P:folic acid-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.30.1130.10; -; 1.
DR InterPro; IPR006156; Dihydroneopterin_aldolase.
DR InterPro; IPR006157; FolB_dom.
DR InterPro; IPR043133; GTP-CH-I_C/QueF.
DR NCBIfam; TIGR00526; folB_dom; 1.
DR PANTHER; PTHR42844; DIHYDRONEOPTERIN ALDOLASE 1-RELATED; 1.
DR PANTHER; PTHR42844:SF10; DIHYDRONEOPTERIN TRIPHOSPHATE 2'-EPIMERASE; 1.
DR Pfam; PF02152; FolB; 1.
DR SMART; SM00905; FolB; 1.
DR SUPFAM; SSF55620; Tetrahydrobiopterin biosynthesis enzymes-like; 1.
PE 4: Predicted;
FT DOMAIN 4..115
FT /note="Dihydroneopterin aldolase/epimerase"
FT /evidence="ECO:0000259|SMART:SM00905"
SQ SEQUENCE 117 AA; 13672 MW; 0BF5F9675534A89D CRC64;
MARIRVKNLL IRTYIGFNPD ELVNKQDVVI NLEIETDIPE SALESDEPED IFNYKVITKK
IIALVQEGRF KLLEVLTKRI LDTIMEDKKV TWARVEVDKP HALRFAESVS MEMEARR
//
