ID X5FVZ7_BEMTA Unreviewed; 149 AA.
AC X5FVZ7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Insulin-like growth factor {ECO:0000313|EMBL:AHW85282.1};
OS Bemisia tabaci (Sweetpotato whitefly) (Aleurodes tabaci).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aleyrodoidea;
OC Aleyrodidae; Aleyrodinae; Bemisia.
OX NCBI_TaxID=7038 {ECO:0000313|EMBL:AHW85282.1};
RN [1] {ECO:0000313|EMBL:AHW85282.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24532462;
RA Guo J.Y., Cheng L., Ye G.Y., Fang Q., Guo J.Y.;
RT "FEEDING ON A BEGOMOVIRUS-INFECTED PLANT ENHANCES FECUNDITY VIA INCREASED
RT EXPRESSION OF AN INSULIN-LIKE PEPTIDE IN THE WHITEFLY, MEAM1.";
RL Arch. Insect Biochem. Physiol. 85:164-179(2014).
CC -!- SUBUNIT: Heterodimer of a B chain and an A chain linked by two
CC disulfide bonds. {ECO:0000256|ARBA:ARBA00011207}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU000406}.
CC -!- SIMILARITY: Belongs to the insulin family.
CC {ECO:0000256|ARBA:ARBA00009034, ECO:0000256|RuleBase:RU000406}.
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DR EMBL; KF055836; AHW85282.1; -; mRNA.
DR RefSeq; XP_018909200.1; XM_019053655.1.
DR AlphaFoldDB; X5FVZ7; -.
DR GeneID; 109038563; -.
DR KEGG; btab:109038563; -.
DR OrthoDB; 3028803at2759; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR Gene3D; 1.10.100.10; Insulin-like; 1.
DR InterPro; IPR016179; Insulin-like.
DR InterPro; IPR036438; Insulin-like_sf.
DR InterPro; IPR016724; Insulin-rel_pep.
DR InterPro; IPR040228; Insulin-relat-peptide_inver.
DR InterPro; IPR022353; Insulin_CS.
DR InterPro; IPR022352; Insulin_family.
DR PANTHER; PTHR13647:SF4; INSULIN-LIKE PEPTIDE 1-RELATED; 1.
DR PANTHER; PTHR13647; INSULIN-LIKE PEPTIDE 2-RELATED; 1.
DR Pfam; PF00049; Insulin; 1.
DR PIRSF; PIRSF018431; Molluscan_insulin_rel_peptide; 1.
DR PRINTS; PR00276; INSULINFAMLY.
DR SMART; SM00078; IlGF; 1.
DR SUPFAM; SSF56994; Insulin-like; 1.
DR PROSITE; PS00262; INSULIN; 1.
PE 2: Evidence at transcript level;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Secreted {ECO:0000256|RuleBase:RU000406};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..149
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004956738"
FT DOMAIN 41..145
FT /note="Insulin-like"
FT /evidence="ECO:0000259|SMART:SM00078"
SQ SEQUENCE 149 AA; 17313 MW; 43C51828C3A76770 CRC64;
MRNQKPMLLL IVTSFVTLIL IDGRIARGQH QFARDARSGA ARYCGKRMAE MLMMVCRGAL
SKRTLQKLDN EYQSLGDETD TRLNLRELDY PGALFGQFYP NEFQIFNKAK ALSTINDENF
RRRRRGIVEE CCYNACSKDD LRLYCAHFK
//
