ID X6LUS5_RETFI Unreviewed; 612 AA.
AC X6LUS5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 22-FEB-2023, entry version 24.
DE SubName: Full=Dynein heavy chain, cytosolic {ECO:0000313|EMBL:ETO04867.1};
GN ORFNames=RFI_32527 {ECO:0000313|EMBL:ETO04867.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO04867.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO04867.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO04867.1}.
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DR EMBL; ASPP01028831; ETO04867.1; -; Genomic_DNA.
DR AlphaFoldDB; X6LUS5; -.
DR EnsemblProtists; ETO04867; ETO04867; RFI_32527.
DR OrthoDB; 166463at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF32; DYNEINS HEAVY CHAIN; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000023152}.
FT DOMAIN 2..101
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 146..285
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 293..563
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
SQ SEQUENCE 612 AA; 70210 MW; 8893637C3D3F481F CRC64;
MQPLQRLAKQ LNRDIRMVPL ESGQTKTGTS VLQSALTSGH WVYLANCHLS ITWMSDLEQL
IESYCTAKNA SKPHPDFRLW LSSKPNPQFP VSILQRSLKI TIEPPSGLKM NMKRLYDSSY
TNMFNKNILV IYHTGLSLQH CNQVHFRKLL FGLTWFHSLL LERRKFGSLG WNAPYNFLDS
DFQTSLSILS LYLNKYKETP WDAIKYLIGD INYGGRVTNA MDRRLMNVYV SQIFCENCVK
SANYMLSELP TFYVPDDGPL KNYQEYIESL PSIDHAGAFG QHPNADTFVH AEDSSTLLDA
LASFQESTNV EQGKLMEETI STLCEELLQS IPVPLDIQEI KRKQQIDDSP LTIVLFQEIE
RYNHLLQVIK KHLILLRKGV QGSIVLSSEM EDSCLKLYNN KVPDMWKNFY PSLKSLGGWI
VDLKLRVHQL HSWAYHTVLC IVLRGKPKVF WLSGFMFPSS FLTVLLQVVA RKQKIAIDHL
NWEYNVINDR DDLNGDTIQM HPKEGAYIRG LYVEGASWNF ADGCLTDSLP MKMTVQMPVI
HFKPVEKKKS AKGMENQSFI CSVDLKSGKV DASELFLSFV AKPSAQNLQL PFEQIHLLFF
LSLSHKKNLL YF
//
