ID X6M5M9_RETFI Unreviewed; 355 AA.
AC X6M5M9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Diphosphate--fructose-6-phosphate 1-phosphotransferase {ECO:0000313|EMBL:ETO09298.1};
DE Flags: Fragment;
GN ORFNames=RFI_28089 {ECO:0000313|EMBL:ETO09298.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO09298.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO09298.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose
CC 1,6-bisphosphate + H(+) + phosphate; Xref=Rhea:RHEA:13613,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:32966, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=2.7.1.90;
CC Evidence={ECO:0000256|ARBA:ARBA00000628};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO09298.1}.
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DR EMBL; ASPP01024158; ETO09298.1; -; Genomic_DNA.
DR AlphaFoldDB; X6M5M9; -.
DR EnsemblProtists; ETO09298; ETO09298; RFI_28089.
DR OrthoDB; 5475590at2759; -.
DR UniPathway; UPA00109; UER00182.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0003872; F:6-phosphofructokinase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.450; -; 1.
DR InterPro; IPR022953; ATP_PFK.
DR InterPro; IPR000023; Phosphofructokinase_dom.
DR InterPro; IPR035966; PKF_sf.
DR PANTHER; PTHR43650; PYROPHOSPHATE--FRUCTOSE 6-PHOSPHATE 1-PHOSPHOTRANSFERASE; 1.
DR PANTHER; PTHR43650:SF1; PYROPHOSPHATE--FRUCTOSE 6-PHOSPHATE 1-PHOSPHOTRANSFERASE SUBUNIT BETA 1; 1.
DR Pfam; PF00365; PFK; 1.
DR PRINTS; PR00476; PHFRCTKINASE.
DR SUPFAM; SSF53784; Phosphofructokinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ETO09298.1}.
FT DOMAIN 94..325
FT /note="Phosphofructokinase"
FT /evidence="ECO:0000259|Pfam:PF00365"
FT REGION 64..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..94
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 355
FT /evidence="ECO:0000313|EMBL:ETO09298.1"
SQ SEQUENCE 355 AA; 39288 MW; 1DEF22FA17161453 CRC64;
MTDETLLGKL RREFVPRIPK SLEHLEKLKF ETGEKTKSIS NQKEISGLFP LTYGQPLLHL
AHSDEEKSLE HSPPPIAYKN TKKKKKKKKK KTNSGQASGG HNVITGLFDA LKHLNGESTM
IGFLDGPIGV IQNKYIKIDK NVVDEYRNTG GFDMIRSGRD KIETSQQQES ALKSVVSHDL
NGLVIIGGDD SNTNAAVLAE YFASQKCKCV PKTIDGDLQN EYIEMSFGFD TAVKTYSEMI
SNICRDAKSA AKSWHFIKLM GRDASHVTLD CALQTHVNIT LIGEEVEKQD LLLHDIADHM
ADVIATRQAK GKDYGIVLIP EGIISFIPSM KALIGELSSL LKKGSSHLKA LDERP
//
