ID   X6MDQ5_RETFI            Unreviewed;      1223 AA.
AC   X6MDQ5;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   22-FEB-2023, entry version 29.
DE   SubName: Full=BEACH domain-containing protein {ECO:0000313|EMBL:ETO11175.1};
GN   ORFNames=RFI_26198 {ECO:0000313|EMBL:ETO11175.1};
OS   Reticulomyxa filosa.
OC   Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC   Reticulomyxidae; Reticulomyxa.
OX   NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO11175.1, ECO:0000313|Proteomes:UP000023152};
RN   [1] {ECO:0000313|EMBL:ETO11175.1, ECO:0000313|Proteomes:UP000023152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24332546;
RA   Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA   Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA   Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT   "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL   Curr. Biol. 0:0-0(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETO11175.1}.
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DR   EMBL; ASPP01022679; ETO11175.1; -; Genomic_DNA.
DR   AlphaFoldDB; X6MDQ5; -.
DR   EnsemblProtists; ETO11175; ETO11175; RFI_26198.
DR   OrthoDB; 47483at2759; -.
DR   Proteomes; UP000023152; Unassembled WGS sequence.
DR   Gene3D; 1.10.1540.10; BEACH domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR000409; BEACH_dom.
DR   InterPro; IPR036372; BEACH_dom_sf.
DR   InterPro; IPR023362; PH-BEACH_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR46108; BLUE CHEESE; 1.
DR   PANTHER; PTHR46108:SF4; BLUE CHEESE; 1.
DR   Pfam; PF02138; Beach; 1.
DR   Pfam; PF14844; PH_BEACH; 1.
DR   SMART; SM01026; Beach; 1.
DR   SUPFAM; SSF81837; BEACH domain; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50197; BEACH; 1.
DR   PROSITE; PS51783; PH_BEACH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000023152}.
FT   DOMAIN          846..1039
FT                   /note="BEACH-type PH"
FT                   /evidence="ECO:0000259|PROSITE:PS51783"
FT   DOMAIN          1090..1223
FT                   /note="BEACH"
FT                   /evidence="ECO:0000259|PROSITE:PS50197"
FT   REGION          548..781
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        548..579
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        580..596
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        597..633
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        659..676
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        690..705
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        715..740
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        741..760
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1223 AA;  142004 MW;  98F9526B34A45984 CRC64;
     MFASNILHLV EICSLTLQNY FAFYLLPRKA TIEKKKAKPV RRHTHVARKL SVLTGNTEVP
     SPSASPNPPA IVQAEKPHWR KERRHSFSGN LAEIVQLRSK AMTIQTNPPV SPRHGPVKAV
     DGKIGTNEQF AKHAHQTSEI GTYGSDKNNS YLEQIPPPSK IARRLLEILQ ACKSALDDRM
     AKDEEENTQN EERASSYQDL ETLYNTCRKA VQSVLIFFLH KSLELANKNR HLEKLLPLVI
     EYQQVLFFTD MSEPDFFFLG LMQVLTKLLT DVARYGDKTN LSQTKERLVQ HCLSVWDCVL
     MYQSHFLARF LSKESELNEK LRLIITKRSL FLQWLRKGGL AKAQTTFQNI FGKVWNERYV
     NEKATLREKF EKDRIQAKTQ HENVLIYEGK LKLIPMNVMY GSGGAVIVKD LQSIEHARQL
     ARQQQFYYRD LFSRNKWFEL IVLKLRVQSA LWLQMASLPW DEAWCIDFVE GPHRMRKILK
     RHTEFIRIYK ANRRQFMQEY YSIHDSYYRR KNKQKAQKRK LNALTTPNNK TRSRYSLALL
     SNDSQNKVNS VFSSGEDESS NVDETSLEKS IGSSTEDQEF VEPNEFKHAE ETSEVDGLET
     IEHEDGDDVG IEIEVEDEDE EEEEQFKDEY DEDDDQFAMV HQGAKVNRNR KNSTLRKRTS
     QVKKHEQEEL EEDTHGESGF TAVTPPPPRT EDEEEEEEEE EDEENNEHKF ETHLFLTNQD
     SQVRSNSKST TSSQLLNHRS NQHNEAKKKV VPKRKAAKEE EDDDEDNDDY GDVGNDEAGA
     DHGKWIEEYH LDDFVDSDEK NTQQEDYTLG NLLPFEQDKD TADAGTHKDE GTLGIVDRIS
     RVLAPGDVFD PKRTYNCSTM SGLNEDHGIV LLCRTAMYFF YRIRIAPETG ELKEIEPNLQ
     NQVAFTTTFD MNEPELGPLL TVKKIRTMMD YLPSIKSNTA IDADDADLRD VSNSKNKGKL
     VVDKHKGGEA TNHMELTEFD GLHENKEPLR YTYDSLREVY KRQYQLQQIA IEFFLLNGSN
     FLLIFPKRNE RDLVFEEVQN ADSFLQRRQR KNQQSEMQNL KTITSHQTSD TLHHIQAAQQ
     RTRFQMVAET LGRTADNISV VTRRWENGHM SNFAYLMFLN TLAGRSYNDI TQYPVFPWIL
     RDYESEVLNL TNPLIYRDLS KPMGAQTEPR ASEFKERFET WDDPTGKAPP WHYGSHYSCA
     AIVLYFLIRL EPFTKLIKNI LYI
//