ID X6MFA5_RETFI Unreviewed; 363 AA.
AC X6MFA5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Dual function enzyme: UDP-glucose 4-epimerase {ECO:0000313|EMBL:ETO12574.1};
GN ORFNames=RFI_24802 {ECO:0000313|EMBL:ETO12574.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO12574.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO12574.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO12574.1}.
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DR EMBL; ASPP01021276; ETO12574.1; -; Genomic_DNA.
DR AlphaFoldDB; X6MFA5; -.
DR EnsemblProtists; ETO12574; ETO12574; RFI_24802.
DR OMA; RSFMYID; -.
DR OrthoDB; 23at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43574; EPIMERASE-RELATED; 1.
DR PANTHER; PTHR43574:SF6; GDP-MANNOSE 3,5-EPIMERASE 1; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000023152}.
FT DOMAIN 8..261
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 363 AA; 41499 MW; 5ABC1DA6C9F33333 CRC64;
MAERKKRICV GGGAGFIGSH LAKRLKEQYG YYVIVADRKQ NEFWKKEEFC NEFHQLDLRS
LKVANTIYFI FIFLCILTKD CDEVFNLAAD MGGMGFIQSN ESVLLFNNTM ISANMLEASR
RNKVKRYFFS GSACCYNEKK QLEVDNPGLK ESDAWPAWPQ DTYGLEKLYA EEMAMIYGRD
FDIVTRIARF HNIYGPHGTW RGGREKAPAA FCRKAAAVDE KEEIEIWGDG KQTRSFCFID
DCVEGIIRLM NSDYDKPVNI GSDEMVSMNE LATMALSFDG KKNKLKHIKG PEGVRGRNSD
NTLIKEVLGW APATSLKVGL KKTYDWIKQQ IAHEREHGSK EDFQKSVIVK QDEALLDDFN
FDV
//
