ID   X6MKS7_RETFI            Unreviewed;       648 AA.
AC   X6MKS7;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=Heat shock protein 70 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=RFI_22752 {ECO:0000313|EMBL:ETO14618.1};
OS   Reticulomyxa filosa.
OC   Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC   Reticulomyxidae; Reticulomyxa.
OX   NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO14618.1, ECO:0000313|Proteomes:UP000023152};
RN   [1] {ECO:0000313|EMBL:ETO14618.1, ECO:0000313|Proteomes:UP000023152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24332546;
RA   Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA   Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA   Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT   "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL   Curr. Biol. 0:0-0(2013).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|RuleBase:RU003322}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETO14618.1}.
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DR   EMBL; ASPP01019913; ETO14618.1; -; Genomic_DNA.
DR   AlphaFoldDB; X6MKS7; -.
DR   EnsemblProtists; ETO14618; ETO14618; RFI_22752.
DR   OrthoDB; 5491443at2759; -.
DR   Proteomes; UP000023152; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 3.30.30.30; -; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375:SF144; ENDOPLASMIC RETICULUM CHAPERONE BIP; 1.
DR   PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU003322};
KW   Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        231..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   648 AA;  73141 MW;  1CB981FE1AF35C4B CRC64;
     MNIYQLGKLV AVSIAIACTI QYHGVYGFSI PEESVVGYVF FFVLFYEGKK KEDSKHILAL
     NTHIQRTMPK TKVKHIIGIS LGGTNSRVGV MTNGKVEIIA NELGNRATPS FVAFTETEVL
     VGDAAKNQAP MNPQNTIFGM KWCVQYVYLY LLLFDKEVQG YIKAWPFQVI DKEDKPYINV
     TYKGEVHLFS PEDICAIILK KMKEIAESYL SENITYAVLT VPAYFEDAQR TVFFFVFVLM
     MACPFFFFKK KKKNWKMAGF SWTRLFLEPY ATANLQKLHT EANITVVHFG GTALGIAAME
     FDEGVYTIMA MSKDIHLGLT DYFVDTFAHK HNVDLRAYPC ALGRLRRACT HAKHALSSET
     QVQVEVANLV DDIDFNETLT RIQFEELNQD LFQKVIDLLD QVLQKSDFKK SDIQQVRFVV
     LSGGSTFIPK IRHIVQEYFS DIEIHFTNNP DETQAISAAI VGDIWTTPIP PLIPLEVVPL
     SIGIETIGGV MTRLLHRNTV IPTIKSRVFT TCRDNQKAMH FRLFAGEYAK IANDIFLAEL
     EITGIEPAPR GTSQIEVTIT VNIQDDVQVD LHARASKTSQ NFTITSISMP SQTFTNNYLD
     YFFSENSELP TNLHQLSEVQ ANLSACLLDS DHPSANEIKL LGAYHSDL
//