ID X6NJ25_RETFI Unreviewed; 395 AA.
AC X6NJ25;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Caspase 3, apoptosis-related cysteine protease a {ECO:0000313|EMBL:ETO25878.1};
GN ORFNames=RFI_11260 {ECO:0000313|EMBL:ETO25878.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO25878.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO25878.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- SIMILARITY: Belongs to the peptidase C14A family.
CC {ECO:0000256|ARBA:ARBA00010134}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO25878.1}.
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DR EMBL; ASPP01008234; ETO25878.1; -; Genomic_DNA.
DR AlphaFoldDB; X6NJ25; -.
DR EnsemblProtists; ETO25878; ETO25878; RFI_11260.
DR OrthoDB; 2873736at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1460; -; 1.
DR InterPro; IPR029030; Caspase-like_dom_sf.
DR InterPro; IPR011600; Pept_C14_caspase.
DR InterPro; IPR001309; Pept_C14_p20.
DR InterPro; IPR015917; Pept_C14A.
DR PANTHER; PTHR22576:SF41; CASPASE 23-RELATED; 1.
DR PANTHER; PTHR22576; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
DR SMART; SM00115; CASc; 1.
DR SUPFAM; SSF52129; Caspase-like; 1.
DR PROSITE; PS50208; CASPASE_P20; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ETO25878.1};
KW Protease {ECO:0000313|EMBL:ETO25878.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152}.
FT DOMAIN 192..289
FT /note="Caspase family p20"
FT /evidence="ECO:0000259|PROSITE:PS50208"
SQ SEQUENCE 395 AA; 46525 MW; 2284BCB95B6FF496 CRC64;
MKWLKDKDEK DKKEIVTNFE KLSDDNFEIW LLKQSKWKND VTKKNIPSIC DATKAFVIYH
STDRLAVQVI VDEKSTELIM RNLTFEELFR QIYNNLEWKY LREMRNKDQR LELADSNDEI
IESDEMVKTE FEKNKRLFKV LWSPIRIEKI KVIKNALVIM IAISEYIDNE IWPNLPNVKE
QDVGNFKQLF EQNLGYEFVC NTNFKMNKED VKEFLIEVIT SRELVKNKQK YDALIVIVSG
HGDKEDVLIT SDGKKTQINS IRTLFDCDRM SSFQNFPKIF FIDACRGTTM PKKENNNTAS
RGRGIMHDGE GFLMVWSTTS GYSVSDLSIF SESIKCLISQ KYQNETLRQM LNEIRNDIKK
KDLCYCLERS DTIDYDIIFQ QRISFSQQLK NVAAK
//
