ID X6NTT1_RETFI Unreviewed; 383 AA.
AC X6NTT1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=RFI_07937 {ECO:0000313|EMBL:ETO29189.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO29189.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO29189.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO29189.1}.
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DR EMBL; ASPP01006197; ETO29189.1; -; Genomic_DNA.
DR AlphaFoldDB; X6NTT1; -.
DR EnsemblProtists; ETO29189; ETO29189; RFI_07937.
DR OrthoDB; 90710at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0019900; F:kinase binding; IEA:InterPro.
DR GO; GO:0019722; P:calcium-mediated signaling; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR045198; CNBL1-10.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23056; CALCINEURIN B; 1.
DR PANTHER; PTHR23056:SF143; CALCINEURIN B-LIKE PROTEIN 8; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 121..156
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 165..200
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 270..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..284
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 383 AA; 43747 MW; BBEC901BF7F7CF47 CRC64;
MGHAPAQNVS QSLEQIKKDQ CEYEYLTKIT HFDVNTLRLL HARFNGIDMS IHNDGVISME
EFARVLGVDR QSLLVQRFFH FIDKSDMGVL NFRNFAVAMS MLRTSYQTLI KTQKTKSNEA
SPQEKMEFSF FLYDMNNDKL IDKEELRKMV CSASEYIDMH LSEEQIEKLV NDTFLICDKD
KNGVIDYNEY CAFCQENPRI LQPFTIDVEN LIQYELESRR KRPTSDTGKG LIRGIPAPKN
NRMKKFGSSV IQKITKNDVD NVEPIHEASD VLRGLDKNES KDETENPSFL PGGGKSSDYN
VNAIMDAEVE SFDKSSTMNT ITMPTEESPI LEWLTETSHY EPKSKKNEQK NNTSTKHKSG
TSSQLDGQSY GGARDDHHAK SSQ
//
