ID Y0KHY7_9PROT Unreviewed; 707 AA.
AC Y0KHY7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:EUJ10923.1};
GN ORFNames=Meth11DRAFT_1754 {ECO:0000313|EMBL:EUJ10923.1};
OS Methylophilaceae bacterium 11.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Methylophilaceae.
OX NCBI_TaxID=1101195 {ECO:0000313|EMBL:EUJ10923.1, ECO:0000313|Proteomes:UP000022668};
RN [1] {ECO:0000313|EMBL:EUJ10923.1, ECO:0000313|Proteomes:UP000022668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=11 {ECO:0000313|EMBL:EUJ10923.1,
RC ECO:0000313|Proteomes:UP000022668};
RG DOE Joint Genome Institute;
RA Chistoserdova L., Huntemann M., Han J., Chen A., Kyrpides N.,
RA Mavromatis K., Markowitz V., Palaniappan K., Ivanova N., Schaumberg A.,
RA Pati A., Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUJ10923.1}.
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DR EMBL; JCKJ01000001; EUJ10923.1; -; Genomic_DNA.
DR AlphaFoldDB; Y0KHY7; -.
DR STRING; 1101195.Meth11DRAFT_1754; -.
DR PATRIC; fig|1101195.3.peg.1714; -.
DR eggNOG; COG5001; Bacteria.
DR Proteomes; UP000022668; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000022668};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 289..421
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 430..683
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 416..443
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 707 AA; 79062 MW; 289829E642224DE6 CRC64;
MLSEFSSSIL LISLMAGALA CFATFGFVAS LYKASPRQYK RLLTVYSALV GVGLFAIHFM
NMRAFNHSYM HELSYLYLLL ALICASTVGV SVLHTANRHT LPIYSLILAG LQTGIAGFGI
FIFFTKAMLL NQFEILLLPA MLAVAIAVGV GILGIITFYW LKSYEGAHRY SVRAFFSILI
SIGILSTHLA FNTSIASTGE YATDSSVLNS SFITMLFAMV LIFVFLTAFI VVVFYDRLNP
NIAKRINFKN TTSTSNTLDS FDPLTKLPNR NALNQHLQLA ANRCDRLNDS MALAYIDLDH
FKPVNDSFGH HVGDLLLIEV AERFNSSIRN CDYIARAGGD EFVAILGEID AHESIVAVVQ
RMIDAVKEPF FIEGHLIEIS CSVGVAIYPR DGNLEKLKVS ADAAMYKAKE NGRNQFRFYD
AEIEQASDEM QKIRKELLDA IEKDQFTLHF QPKVIAKTQA PAGAEALLRW NHPTKGLLTP
IYFIEAAERF GFIDKINNWV LMQACKTIAD AREHGIALSL SVNLSRQQFR NAYLVDDIKK
VMEQYQVPPQ SLIFEISETH AIHNQNQFKK LLSKFKFAHL KVSIDDFGLH PFSLTYLQNL
EVSEVKLDKS FTSGVAKYSS ALAIVDAVVK LAHALNLTVV AEGVETDEQR QALTTTGCDQ
MQGYFFSKPV PTAQLFTIYH TLNHRFSEVG EYSINDYLPQ EAYPEDT
//
