ID   Y0KJN2_9PROT            Unreviewed;       448 AA.
AC   Y0KJN2;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=EAL domain-containing protein {ECO:0000313|EMBL:EUJ11503.1};
GN   ORFNames=Meth11DRAFT_2348 {ECO:0000313|EMBL:EUJ11503.1};
OS   Methylophilaceae bacterium 11.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Methylophilaceae.
OX   NCBI_TaxID=1101195 {ECO:0000313|EMBL:EUJ11503.1, ECO:0000313|Proteomes:UP000022668};
RN   [1] {ECO:0000313|EMBL:EUJ11503.1, ECO:0000313|Proteomes:UP000022668}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=11 {ECO:0000313|EMBL:EUJ11503.1,
RC   ECO:0000313|Proteomes:UP000022668};
RG   DOE Joint Genome Institute;
RA   Chistoserdova L., Huntemann M., Han J., Chen A., Kyrpides N.,
RA   Mavromatis K., Markowitz V., Palaniappan K., Ivanova N., Schaumberg A.,
RA   Pati A., Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EUJ11503.1}.
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DR   EMBL; JCKJ01000001; EUJ11503.1; -; Genomic_DNA.
DR   AlphaFoldDB; Y0KJN2; -.
DR   STRING; 1101195.Meth11DRAFT_2348; -.
DR   PATRIC; fig|1101195.3.peg.2293; -.
DR   eggNOG; COG2200; Bacteria.
DR   Proteomes; UP000022668; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   Pfam; PF00563; EAL; 1.
DR   SMART; SM00052; EAL; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   PROSITE; PS50883; EAL; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000022668};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          184..438
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   448 AA;  50633 MW;  0EF14819979E97AD CRC64;
     MAIESNPLIK HQDKLTYLLI IASIVITVVA IAWTIFFISI RDWLSVGVES TLIALGYIGY
     SSAKRNNTKV IAHILFPLLF IVMCIVCIFF DVPNTAVPRS NHHYFLPMVL YAYVLYQDEH
     PYLKIAVPAL ISLAFLMFAS THTGINLSGM TNDHRLVGVW ITNSVALMML FLVALIMQSD
     FKVRHTLELE LSKALLKNEI ELYFQPQVDE RGRTLGAEAL ARWQHPTFGT IEPDVFIPLA
     EKSELILHLG KYVLASACHQ LTLWAQNETT AQLTLSVNIS VKQFQSTEFV PHIITLLNEA
     KVNAHKLQLE ITESIFAHDL ETIQVKMTQL KSYGIKFSLD DFGTGYSSLA YVKKLPLDEL
     KIDKSFIKEV LTSVNDASIT KMIISLAHEL HIAIIAEGVE TPEQQQFLIN NGCLNFQGYL
     YSRPLPIAEF NVFTLANNQQ PQPYFQYP
//