ID Y577_METJA Reviewed; 162 AA.
AC Q57997;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE RecName: Full=Universal stress protein MJ0577;
DE Short=USP MJ0577;
GN OrderedLocusNames=MJ0577;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) IN COMPLEX WITH ATP.
RX PubMed=9860944; DOI=10.1073/pnas.95.26.15189;
RA Zarembinski T.I., Hung L.-W., Mueller-Dieckmann H.-J., Kim K.-K.,
RA Yokota H., Kim R., Kim S.-H.;
RT "Structure-based assignment of the biochemical function of a hypothetical
RT protein: a test case of structural genomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 95:15189-15193(1998).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Note=Binds 1 Mn(2+) ion per subunit.;
CC -!- SUBUNIT: Homodimer.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- SIMILARITY: Belongs to the universal stress protein A family.
CC {ECO:0000305}.
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DR EMBL; L77117; AAB98568.1; -; Genomic_DNA.
DR PIR; A64372; A64372.
DR PDB; 1MJH; X-ray; 1.70 A; A/B=1-162.
DR PDBsum; 1MJH; -.
DR AlphaFoldDB; Q57997; -.
DR SMR; Q57997; -.
DR STRING; 243232.MJ_0577; -.
DR PaxDb; 243232-MJ_0577; -.
DR EnsemblBacteria; AAB98568; AAB98568; MJ_0577.
DR KEGG; mja:MJ_0577; -.
DR eggNOG; arCOG00449; Archaea.
DR HOGENOM; CLU_049301_11_2_2; -.
DR InParanoid; Q57997; -.
DR PhylomeDB; Q57997; -.
DR EvolutionaryTrace; Q57997; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd00293; USP_Like; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR006015; Universal_stress_UspA.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR46268; STRESS RESPONSE PROTEIN NHAX; 1.
DR PANTHER; PTHR46268:SF6; UNIVERSAL STRESS PROTEIN A-RELATED; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR01438; UNVRSLSTRESS.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 1: Evidence at protein level;
KW 3D-structure; ATP-binding; Cytoplasm; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..162
FT /note="Universal stress protein MJ0577"
FT /id="PRO_0000147446"
FT BINDING 11
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000269|PubMed:9860944,
FT ECO:0007744|PDB:1MJH"
FT BINDING 41
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000269|PubMed:9860944,
FT ECO:0007744|PDB:1MJH"
FT BINDING 127..133
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000269|PubMed:9860944,
FT ECO:0007744|PDB:1MJH"
FT BINDING 141..143
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000269|PubMed:9860944,
FT ECO:0007744|PDB:1MJH"
FT STRAND 7..11
FT /evidence="ECO:0007829|PDB:1MJH"
FT HELIX 16..27
FT /evidence="ECO:0007829|PDB:1MJH"
FT STRAND 35..43
FT /evidence="ECO:0007829|PDB:1MJH"
FT HELIX 44..46
FT /evidence="ECO:0007829|PDB:1MJH"
FT HELIX 67..94
FT /evidence="ECO:0007829|PDB:1MJH"
FT STRAND 98..106
FT /evidence="ECO:0007829|PDB:1MJH"
FT HELIX 108..118
FT /evidence="ECO:0007829|PDB:1MJH"
FT STRAND 122..128
FT /evidence="ECO:0007829|PDB:1MJH"
FT HELIX 141..149
FT /evidence="ECO:0007829|PDB:1MJH"
FT STRAND 154..157
FT /evidence="ECO:0007829|PDB:1MJH"
SQ SEQUENCE 162 AA; 18339 MW; 0A1060E6A2E6E1F4 CRC64;
MSVMYKKILY PTDFSETAEI ALKHVKAFKT LKAEEVILLH VIDEREIKKR DIFSLLLGVA
GLNKSVEEFE NELKNKLTEE AKNKMENIKK ELEDVGFKVK DIIVVGIPHE EIVKIAEDEG
VDIIIMGSHG KTNLKEILLG SVTENVIKKS NKPVLVVKRK NS
//
