ID YJN2_SCHPO Reviewed; 449 AA.
AC Q9P7K3;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE RecName: Full=Uncharacterized kinase C24B10.02c;
DE EC=2.7.1.-;
GN ORFNames=SPCC24B10.02c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-420, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the NAD kinase family. {ECO:0000305}.
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DR EMBL; CU329672; CAB76211.1; -; Genomic_DNA.
DR PIR; T50409; T50409.
DR RefSeq; NP_588005.1; NM_001022996.2.
DR AlphaFoldDB; Q9P7K3; -.
DR SMR; Q9P7K3; -.
DR BioGRID; 275821; 6.
DR STRING; 284812.Q9P7K3; -.
DR iPTMnet; Q9P7K3; -.
DR MaxQB; Q9P7K3; -.
DR PaxDb; 4896-SPCC24B10-02c-1; -.
DR EnsemblFungi; SPCC24B10.02c.1; SPCC24B10.02c.1:pep; SPCC24B10.02c.
DR GeneID; 2539251; -.
DR KEGG; spo:SPCC24B10.02c; -.
DR PomBase; SPCC24B10.02c; -.
DR VEuPathDB; FungiDB:SPCC24B10.02c; -.
DR eggNOG; KOG2178; Eukaryota.
DR HOGENOM; CLU_008831_10_3_1; -.
DR InParanoid; Q9P7K3; -.
DR OMA; RLECKIY; -.
DR PhylomeDB; Q9P7K3; -.
DR PRO; PR:Q9P7K3; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0003951; F:NAD+ kinase activity; IBA:GO_Central.
DR GO; GO:0019674; P:NAD metabolic process; ISO:PomBase.
DR GO; GO:0006741; P:NADP biosynthetic process; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR HAMAP; MF_00361; NAD_kinase; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR002504; NADK.
DR PANTHER; PTHR20275; NAD KINASE; 1.
DR PANTHER; PTHR20275:SF0; NAD KINASE; 1.
DR Pfam; PF01513; NAD_kinase; 1.
DR Pfam; PF20143; NAD_kinase_C; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Kinase; NAD; NADP; Nucleus; Phosphoprotein; Reference proteome;
KW Transferase.
FT CHAIN 1..449
FT /note="Uncharacterized kinase C24B10.02c"
FT /id="PRO_0000316602"
FT MOD_RES 420
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 449 AA; 50609 MW; 1B4DC3BCA99A75D7 CRC64;
MATKVEEINK LKKKNLHFRQ CSADSLSNSS MQFDLSGLNT PVGELATSNL PSPAHPPFGE
LHQESRTSNS SAMHIENVVA SRLMYNEVAN GSFALEPKNI LVVTKPRKHS LVYKTAEITK
YILTIGTPET KVYVDMRLAR SKRFSAHNIA KEANTDIDRI KYWNPYICLI KPSIFDLAIT
IGDNSTLLYT SWLFQKIGPP VLSFSDDDVP GFLTHFSLSN YQQHLYQVLT QNVSLRFCSR
LQCSFHKYDE KTKQYSLAST TYSLDEILIS RGEHPFISNL NVYNNSELMT VVQADGLVVA
TPTGSTNISA NAGGSLVHPA LNAILVTPVC PHTLSFRPII LPDYNVLNVE IPLDSRSSAF
FSVDRHESVE MHRGDYLSIV TSHYPFTTIQ NPGYQWTKVL EDKFNWNVRE RQKPFSRKPS
LSDVKDTSDD KFDITDNSYC REFSADIDG
//
