ID YUSO_BACSU Reviewed; 155 AA.
AC O32181;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 132.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator YusO;
GN Name=yusO; OrderedLocusNames=BSU32870;
OS Bacillus subtilis (strain 168).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL009126; CAB15276.1; -; Genomic_DNA.
DR PIR; H70021; H70021.
DR RefSeq; NP_391166.1; NC_000964.3.
DR RefSeq; WP_003242592.1; NZ_JNCM01000033.1.
DR PDB; 1S3J; X-ray; 2.25 A; A/B=1-155.
DR PDBsum; 1S3J; -.
DR AlphaFoldDB; O32181; -.
DR SMR; O32181; -.
DR STRING; 224308.BSU32870; -.
DR PaxDb; 224308-BSU32870; -.
DR EnsemblBacteria; CAB15276; CAB15276; BSU_32870.
DR GeneID; 935923; -.
DR KEGG; bsu:BSU32870; -.
DR PATRIC; fig|224308.179.peg.3563; -.
DR eggNOG; COG1846; Bacteria.
DR InParanoid; O32181; -.
DR OrthoDB; 327696at2; -.
DR PhylomeDB; O32181; -.
DR BioCyc; BSUB:BSU32870-MONOMER; -.
DR EvolutionaryTrace; O32181; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 1.10.287.100; -; 1.
DR Gene3D; 1.20.5.420; Immunoglobulin FC, subunit C; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR42756; TRANSCRIPTIONAL REGULATOR, MARR; 1.
DR PANTHER; PTHR42756:SF1; TRANSCRIPTIONAL REPRESSOR OF EMRAB OPERON; 1.
DR Pfam; PF01047; MarR; 1.
DR PRINTS; PR00598; HTHMARR.
DR SMART; SM00347; HTH_MARR; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50995; HTH_MARR_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..155
FT /note="Uncharacterized HTH-type transcriptional regulator
FT YusO"
FT /id="PRO_0000360555"
FT DOMAIN 4..140
FT /note="HTH marR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
FT DNA_BIND 54..77
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
FT HELIX 4..32
FT /evidence="ECO:0007829|PDB:1S3J"
FT HELIX 37..49
FT /evidence="ECO:0007829|PDB:1S3J"
FT STRAND 50..53
FT /evidence="ECO:0007829|PDB:1S3J"
FT HELIX 54..61
FT /evidence="ECO:0007829|PDB:1S3J"
FT HELIX 65..77
FT /evidence="ECO:0007829|PDB:1S3J"
FT STRAND 80..85
FT /evidence="ECO:0007829|PDB:1S3J"
FT STRAND 92..97
FT /evidence="ECO:0007829|PDB:1S3J"
FT HELIX 99..120
FT /evidence="ECO:0007829|PDB:1S3J"
FT HELIX 125..143
FT /evidence="ECO:0007829|PDB:1S3J"
SQ SEQUENCE 155 AA; 17400 MW; 21B31E4B1E4ED0BD CRC64;
MKSADQLMSD IQLSLQALFQ KIQPEMLESM EKQGVTPAQL FVLASLKKHG SLKVSEIAER
MEVKPSAVTL MADRLEQKNL IARTHNTKDR RVIDLSLTDE GDIKFEEVLA GRKAIMARYL
SFLTEEEMLQ AAHITAKLAQ AAETDEKQNM KRGNG
//
