KEGG   Vibrio cholerae O1 MJ-1236: VCD_001985
Entry
VCD_001985        CDS       T00903                                 
Name
(GenBank) aspartokinase/homoserine dehydrogenase
  KO
K12524  bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
Organism
vcj  Vibrio cholerae O1 MJ-1236
Pathway
vcj00260  Glycine, serine and threonine metabolism
vcj00261  Monobactam biosynthesis
vcj00270  Cysteine and methionine metabolism
vcj00300  Lysine biosynthesis
vcj01100  Metabolic pathways
vcj01110  Biosynthesis of secondary metabolites
vcj01120  Microbial metabolism in diverse environments
vcj01230  Biosynthesis of amino acids
Module
vcj_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vcj_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
vcj_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:vcj00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    VCD_001985
   00270 Cysteine and methionine metabolism
    VCD_001985
   00300 Lysine biosynthesis
    VCD_001985
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    VCD_001985
Enzymes [BR:vcj01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     VCD_001985
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     VCD_001985
SSDB
Motif
Pfam: AA_kinase Homoserine_dh NAD_binding_3 ACT_7 ACT
Other DBs
NCBI-ProteinID: ACQ60154
Position
1:1072338..1074815
AA seq 825 aa
MHLEEGMRVLKFGGSSLADPERFLRAADIIANNAQQEEVAVVLSAPGKTTNKLVAVIESA
LRQGEVEAQIVELESSFYALLDGIKAQLPNLDDSAYQQQVHSSMTQLRQFVHGITLLGMC
PDNVNARIISKGERVSIQLMKAVMEAKGLPANLVDPVKYLLAKGDHLEAMVDVEISTQRF
RQAPLPQQHVNIMPGFTAGNAQGELVCLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYN
CDPRLVDDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFQIPCLIKNSFNPQGAGTL
IGQDTGEDKLAIKGITTLSNLTMVNVSGPGMKGMVGMASRVFGAMSAADVSIVLITQSSS
EYSISFCIEAQHKALAQQALADAFELELKDGLLEPVEFVDNVAIITLVGDGMRTSRGVAS
QFFSSLAEVHVNVIAIAQGSSERAISAVIPDDKISEAIKACHENLFNSKHFLDVFVVGVG
GVGGELVDQIQRQQAKLAEKGIMMRVCGLANSKGMLLDSQGLPLEQWRDRMINADQAFSL
ENLVALVQRNHIINPVLVDCTSSDEIANQYADFLAAGFHVVTPNKKANTASMSYYHQLRN
VARHSRRKLMYETTVGAGLPVIENLQNLIAAGDELEKFSGILSGSLSFIFGKLDEGMTLS
QATQLAKEKGFTEPDPRDDLSGMDVARKLLILAREAGYELELSDVDVEQALPAGFDASGS
VEEFMARLAQADAAFAERVAQAKAEGKVLRYVAQIVDGQCQVRIVAVDENDPMFKVKEGE
NALAFYSRYYQPIPLVLRGYGAGSEVTAAGVFSDVMRTLGWKLGV
NT seq 2478 nt   +upstreamnt  +downstreamnt
atgcatttggaggaagggatgcgagtattaaagtttggaggttcatcgctggcggatccg
gagcgttttctacgcgctgccgatatcatcgcgaataacgcacagcaggaagaggtggcc
gttgtcctctctgctccgggaaaaaccaccaataaattggtggcagtgattgaaagtgct
ttacgtcagggagaggtggaagcgcaaatcgtagagctagagagctcattctatgccttg
cttgatggcattaaagcgcagctcccgaatttggatgacagtgcttatcaacagcaagtg
cactcttccatgactcagttacgccagtttgtgcatggcattacgttgctcggtatgtgt
ccagacaatgtgaatgcacgcattatcagtaaaggtgaacgcgtttccattcaattgatg
aaagcggtgatggaagccaaaggtctgccagcgaatttggttgaccccgttaaatacctg
cttgccaaaggggatcatcttgaagctatggtcgatgtggaaatctcgactcagcgtttc
agacaagcaccattgccacaacagcacgtcaatatcatgccgggctttactgcgggtaat
gcacagggtgagttggtctgtttagggcgtaacggttcggattactcagccgcagtactg
gctgcctgtttacgtgcggattgttgtgaaatctggacggatgtggatggagtttataac
tgcgatccgcgtttggtcgatgatgcgcgtcttttgaaatcccttagctatcaagaggcg
atggagctttcttacttcggagcatctgtgttgcatccgaagaccattgcaccgattgct
caatttcaaatcccttgcctgatcaaaaacagcttcaatccacaaggtgcgggcaccttg
attggccaagacactggcgaagataaactcgcgatcaaaggcattaccactctgagcaat
ctgaccatggtcaacgtttctggtccaggaatgaaaggcatggtggggatggcgagccgc
gtgtttggcgcgatgtcagcggcagatgtgtcgatcgtgctcattactcaatcttcttcg
gaatacagcatcagtttctgtatcgaagcacaacataaagctttggcacagcaagcgctg
gcggatgcatttgaactggaactcaaagatggcctgcttgagccggttgagtttgtcgat
aacgtcgccatcatcacgctggttggtgatggtatgcgtacctctcgcggtgtcgcgtcg
caatttttctcatctctggccgaagtacacgtcaacgtgattgcgattgcccaaggctct
tctgagcgtgcgatttcagcggtgatccccgatgataagatttcagaagcgatcaaggcc
tgtcacgaaaacctcttcaactctaaacactttttagatgtgtttgtggtcggtgttggt
ggcgtgggcggtgagttggtggatcaaattcagcgtcaacaagccaagcttgcggaaaaa
ggcatcatgatgcgcgtttgtggcctcgctaacagtaaaggcatgctgcttgatagccaa
ggcttgccgttagagcagtggcgcgatcgtatgatcaatgcggatcaagcgttcagttta
gagaatctggtggctttggtgcagcgtaatcacatcattaacccagtattggtggattgc
acgtccagtgatgagattgctaaccagtatgcggatttcctcgccgcgggtttccatgtg
gtgaccccgaacaagaaagccaataccgctagcatgagttattaccatcagctacgtaat
gtggctcgtcattcgcgtcgcaaactgatgtatgaaactacagttggcgcgggtctaccc
gttatcgaaaacttgcaaaacctaattgcagcaggggatgagctggaaaaattcagcggt
attctctcaggttctctctcctttatcttcggtaaattggatgaaggcatgaccttgagc
caagcaacgcagcttgctaaagagaaaggctttacagagccagatccgcgcgatgatctc
tctggtatggatgtggcgcgcaagttactgattttggcgcgtgaagcagggtacgaattg
gagctgagcgatgtggatgttgaacaagcactgcccgctggctttgatgcttcaggcagt
gttgaggagttcatggctcgtttagcgcaagccgatgccgcgtttgccgagcgagtggcg
caagccaaagccgaaggcaaagtgcttcgctatgtggcgcaaatcgtcgatggccagtgc
caagtgcggattgtcgcggttgatgaaaacgatcctatgttcaaagtcaaagaaggtgaa
aacgcgctggctttctacagccgttactatcagccaatcccattggtattacgtggttac
ggcgcgggttctgaagtgactgctgcaggcgtgttctcagatgtgatgcgtacactcggt
tggaaattaggggtttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (5)   
   Pfam (5)   
All databases (40)   

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