KEGG   Xenopus laevis (African clawed frog): 108696679
Entry
108696679         CDS       T01010                                 
Symbol
sphk2.L
Name
(RefSeq) sphingosine kinase 1
  KO
K04718  sphingosine kinase [EC:2.7.1.91]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla00600  Sphingolipid metabolism
xla01100  Metabolic pathways
xla04020  Calcium signaling pathway
xla04148  Efferocytosis
xla04370  VEGF signaling pathway
xla04371  Apelin signaling pathway
Module
xla_M00100  Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:xla00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    108696679 (sphk2.L)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    108696679 (sphk2.L)
   04371 Apelin signaling pathway
    108696679 (sphk2.L)
   04020 Calcium signaling pathway
    108696679 (sphk2.L)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    108696679 (sphk2.L)
Enzymes [BR:xla01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphingosine kinase
     108696679 (sphk2.L)
SSDB
Motif
Pfam: DAGK_cat YegS_C
Other DBs
NCBI-GeneID: 108696679
NCBI-ProteinID: XP_018081753
Xenbase: XB-GENE-17346103
UniProt: A0A1L8FMX6 A0A974HD06
Position
7L:110129780..110155350
AA seq 593 aa
MENRQSSETLLHGEFGVYPSKGIRYALSLTHTGLHIQRLVPKPEDDQRLVLPLSDMVGCH
TLRSHSSGDAFAYFSIYYYPLKKKKVTMGSSRIRQRLVRTFRVDEESEYNKNLVVAEKWA
TAIKCLIQEIPIGSETEFVPELLPRARRLMLLLNPCGGRGNSLQQCQTHILPMLTEAEIS
YNLVQTERQNHARELVQGINLEEWDGIVVISGDGLLYEVINGLMERPDWEDAIKMPLGIL
PCGSGNALAGAINYNAGFDQAMGSELLLNCILLLCRGTVIPMDMVSVTTCSGIRSFSFLS
VAWGFISDVDIESEKYRHMGSARFTVGTMVRVASLRTYRGRLSYLPVLDAHRPICRSITL
SPNGSLAPFQRSQLHRTISDIGLCEERNVMYKRSSAALDTNELPSFETSPSPSSPTALHS
SSFNFDSLSDDPSDQDSVYSKDLKPQRHHQVNGPKDDLLPPLGQPLPKNWIIVEDDFVLV
LAIYQSHLGADLFTAPFSTFDDGLIHLFFVKAGISRAALVRLFLAMEKGTHFETECPYLT
HIPVRAFRLEPLTRKGIITVDGERVEYGPIQAQLHKGLSNLITGSCKVRMAPF
NT seq 1782 nt   +upstreamnt  +downstreamnt
atggaaaacagacagtcatccgaaacccttctccacggagaattcggagtctacccgtcc
aaaggtattcgatatgcacttagcctgacccacacaggcctccatatccagagactggtc
ccaaagccggaggatgaccaacgcctcgtgttgccgctcagcgacatggtgggctgtcac
actctgcgcagtcatagctccggggatgcgtttgcctatttttccatttattactatccg
ctcaagaagaaaaaggtcaccatgggatccagccgcatccgacagagattggtccggaca
ttccgcgtggacgaagaatcagaatataacaaaaaccttgttgttgctgagaagtgggca
actgcgataaagtgcctgattcaggaaattcctataggcagtgaaacagaatttgttcct
gagcttctgcccagagcccgcagattaatgcttttgctaaatccgtgtggaggaagaggg
aattccctccagcagtgtcagacccacatactgcccatgctgacggaggcagaaatcagc
tataatctcgtacagacagagagacagaaccacgctcgagagctagtgcaagggatcaat
ttggaggaatgggatggtatagttgtcatctccggggacggactgctctatgaggttatt
aacggtttgatggaacgccccgactgggaagatgccataaaaatgccgttgggaattctc
ccctgtggctcaggaaatgctttggcgggagccatcaactacaatgcagggtttgatcag
gcaatggggtctgagctgctgctgaactgcatcttgctgctgtgccgtggtactgttatt
cctatggacatggtgtctgtgacaacctgctctggaatccgttctttctcattccttagt
gtagcctggggttttatctctgacgtggacatagagagcgagaagtaccgtcacatgggt
tcagctcgtttcacagtcggaactatggtaagggtagcctcactgcggacttacagaggc
cgcctgtcctatctgccagttttggatgctcaccgccccatttgcaggagcatcactctg
tctcccaatgggagtttagctccgtttcagcgctcccagttgcaccgtacaatatcagac
attggactgtgtgaggagcggaatgtcatgtataagcgaagttctgctgctctcgacacc
aatgagttgcccagttttgagacttcgccatctccaagttcaccaacagccttgcactcc
tccagcttcaactttgactccctctcggatgacccttctgatcaggattctgtgtattcc
aaagacttaaagcctcaaaggcaccatcaggtaaatggacccaaggacgatctcttgcct
cctttggggcaaccgctgcccaagaactggataatcgtggaagacgattttgtcttagtg
ttggccatttatcagagccatttaggggccgatttgttcacagctccattttccactttt
gacgatggtttaatccaccttttctttgtaaaagccggtatctctcgtgcagcccttgtg
cgcctcttcctggccatggaaaaaggtacacactttgagactgaatgtccatacctcacc
catattcccgttcgagccttccgcttggagccgctcacacgaaagggaattattactgtg
gatggtgagcgggtagaatacgggcctatccaggctcagctacacaaaggactaagtaac
cttatcactggatcttgcaaagtccgtatggctccattctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (45)   

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