KEGG   Xenopus tropicalis (tropical clawed frog): 100494646
Entry
100494646         CDS       T01011                                 
Symbol
npc1
Name
(RefSeq) NPC intracellular cholesterol transporter 1
  KO
K12385  Niemann-Pick C1 protein
Organism
xtr  Xenopus tropicalis (tropical clawed frog)
Pathway
xtr03265  Virion - Ebolavirus and Lyssavirus
xtr04142  Lysosome
Brite
KEGG Orthology (KO) [BR:xtr00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03265 Virion - Ebolavirus and Lyssavirus
    100494646 (npc1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    100494646 (npc1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:xtr02000]
    100494646 (npc1)
Transporters [BR:xtr02000]
 Solute carrier family (SLC)
  SLC65: NPC-type cholesterol transporter
   100494646 (npc1)
SSDB
Motif
Pfam: Patched NPC1_N Sterol-sensing MMPL ACR_tran Folate_rec
Other DBs
NCBI-GeneID: 100494646
NCBI-ProteinID: XP_004915269
Xenbase: XB-GENE-984654
UniProt: A0A6I8R5B9
Position
6:complement(109082364..109126608)
AA seq 1283 aa
MFTWKHQSLIPLFFLTTLWLPGRVSSQHCVWYGECGNSTLEDKRLNCRYSGPPISLPEEG
HTLLQQLCPSLYYGNNTVCCDVQQLNTLNSNLQLPLQFLSRCPSCFYNFMTMFCELTCSP
HQSEFLNVTQTEPFVGPSPQRANESIVAMEYYIGEQFANAMYNACKDVEAPSSNVKALAL
LCGKDVKDCNATNWIQYMFSKDNGQVPFTITPIFSDDPVTSMLPMNNATKGCDEPVEEGG
ASCSCQDCALSCGPVPQPPPLPPPWLIFGLDAMAVIMWIVYVVFLLLFSAVIIGSWCYRK
KNIVSEYAPIDSTLAYSVNSTPIAGEPSCCDRLGERLENFLRIGFTKWGSICVRKPWIVI
FFSVLLIVICCFGLKYMRITTDPVELWSDPHSQARQEKEYFDSHFGPFFRTEQLIITAPN
SSVHNYSPYPSGSDVPFGPPLDFNILAQVLELQNGIENLKAYYNNETVMLKDICLAPLAP
YNNNCTIFSVLNYFQNSFSVLNHSIQDDFYVYADYHTHFLYCVRSPASLNDTSVLHDPCL
GTFGGPIFPWLVLGGYDDENYNNATALVITFPVNNFRNDTEKLNRAKAWELEFIKFVENY
SNPNLSISFSAERSIEDEINRESKSDVTTVVISYALMFVYISLALGQIGHCSSILVDSKI
SLGIAGILIVLSSVACSLGIFSYAGVSLTLIVIEVIPFLVLAVGVDNIYIIVQRYQRDER
LHDETLDQQIGRILGDVAPSIFLSAFAETVAFFLGALSSMPAVRTFSLFAGMAVFLDFLL
QITCFISLLSLDIRRQEKNRLDILCCVPGCKRNRGTDKPKSWLFLFFKKLYAPVLMKDWI
RPIVVSVFVGILSFSIAVVNKVEIGLDQSLSMPDDSYMLDYFGSLSTYLHTGPPVYFVVE
EGHNYTTKEGQDKVCGGAGCNNNSLVQEIYTAAGISNYTRIGYAPSSWIDDYFDWVKPQS
TCCRIYNNTDQFCNASVVNASCLSCRSYTPEGKRKPVGEDFMHFLPMFLSDNPNPKCGKG
GHAAYGSAVDLLDSNTNVGATYFMTYHTILKNSTDFIDAMRKARTIAQNITDNMDIPGKK
YKVFPYSIFYVFYEQYLTIVDDTIFNLCVSLAAVFFVTVILLGFELWSAVLMCITISMIL
VNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHVTRAFSVSTRGNRVQRAEDALAHMG
SSVFSGITLTKFVGIGVLGLSKSQIFKIFYFRMYLAMVLLGAAHGLIFLPVLLSYLGPQV
NKAKVQAALQRARGTEQERLFNH
NT seq 3852 nt   +upstreamnt  +downstreamnt
atgttcacctggaagcaccagtccctgataccgctcttcttcctaacaaccctgtggctt
cctgggcgggtatcttcccagcactgtgtctggtatggggagtgtggcaattcaacatta
gaagacaaacggttaaactgtcgatactcggggcctcctatctccttgcctgaggaagga
catacactgctacagcaactttgcccatcactttattatggaaataacacagtttgctgt
gatgtccagcaactcaacacacttaacagcaatctccagcttccattgcagtttctttca
agatgcccttcttgtttttataatttcatgaccatgttctgtgagctgacctgcagtccc
catcagtcagagtttctaaatgttacccagactgaaccatttgttgggcctagtcctcaa
agggcaaatgaaagcattgtggccatggagtattacataggagaacaatttgctaatgcg
atgtacaatgcatgcaaggatgtagaagccccctcgagtaatgtcaaggctttggctttg
ctgtgtggaaaggatgtcaaggactgtaatgctactaactggattcagtacatgttcagc
aaagataatgggcaggttccttttaccatcacacctatcttttcagatgatcctgtgact
tccatgcttcccatgaacaacgccaccaagggctgcgatgagcctgtggaagaaggcggg
gcttcctgtagttgtcaggactgcgctctttcttgtggtcctgtgccccagcctccacca
cttcctcctccatggcttatatttggcttggatgctatggctgtcatcatgtggatagtt
tatgttgtgttcttactactcttttctgcagtcattattggatcgtggtgttacaggaaa
aagaatattgtctcagaatatgctcctattgatagcactttagcatattctgtcaattcc
actccaatagcaggagagccttcgtgctgtgaccggcttggtgaaagactcgagaacttt
cttcgaattggatttacaaagtggggttctatttgcgtccggaaaccatggattgttatc
tttttctctgtgcttttaattgtgatatgttgctttggcctcaaatacatgaggattact
actgatcctgttgaactctggtcagatcctcacagccaggctcggcaagaaaaggaatat
tttgactctcactttggacccttctttcgcactgaacaactaatcatcactgcccccaac
agttcagtccacaattactcaccatatccttctggcagtgatgtgccttttggcccacct
ctagactttaatattcttgctcaagtcttggagttacaaaatggcattgaaaacctaaaa
gcttattacaataatgagactgtaatgttaaaagacatctgtttggctccattggcccca
tacaacaacaactgcacaattttcagcgttctcaactatttccagaacagcttctctgtg
ctgaatcattccatacaggatgatttctatgtttatgctgattaccacactcacttctta
tactgtgtgcgatctccagcatctttgaatgacacatcagtactccatgatccctgcctg
ggaacatttggtggccccatatttccatggctggttcttggaggatatgatgatgaaaat
tataataatgccaccgccctggtgattacttttccagtaaataatttccgcaacgacaca
gaaaaattgaatagagcaaaggcttgggaattagagtttatcaaatttgtggaaaattat
agcaatcccaatctgtccatttcattctctgccgagagaagcattgaagatgagataaac
cgtgaaagtaaaagtgatgttactactgttgtcatcagttatgccttaatgtttgtctac
atatccttggctttgggtcagattggccactgcagtagtatcttggtggactctaagatc
tcgctgggtattgctggtattctgattgtgctcagttcagtagcctgctctctgggtatc
ttcagctatgctggcgtgtcactcactcttattgtcattgaggtgatcccatttctggtg
ctagctgttggagttgacaacatatacattattgtgcagagatatcagagagatgagcgt
cttcatgatgagactctggaccagcagattggcagaatactgggagatgtggcgccgagt
atatttctgtcagcttttgccgaaacggttgccttttttttgggagcattgtcctctatg
ccagccgtgcggacattttcactctttgctgggatggccgtgtttctagacttcctcctt
cagatcacctgcttcatcagccttcttagtctggacatcaggcgacaagagaaaaaccgc
ttagatatcctttgctgtgtgcctggatgcaagagaaaccgtggcactgacaaaccgaag
agctggctgtttttgttcttcaaaaagctttatgcccctgtactgatgaaggattggata
agacctattgtggtatccgtttttgttggaatcctgtcctttagcattgcggttgtcaac
aaagtagaaataggtcttgatcagtctctctccatgcctgatgattcctacatgctagat
tattttggctcactcagcacatacctccatactggccccccagtgtattttgtagttgag
gaaggacataattataccacaaaggaaggacaggacaaggtgtgtggtggagctggatgc
aataacaattcattggtgcaagagatctacaccgctgctgggataagcaactatacaagg
atcggatacgcaccttcctcttggattgacgattactttgattgggtgaagccccagtct
acttgctgtcgaatatataataacacagatcaattctgtaatgcttcagtggttaacgca
tcctgcttatcatgccggtcctacactccagaaggaaagcgcaaaccagttggagaggat
tttatgcatttcctgcccatgtttctctctgataatccaaaccccaaatgtgggaaaggg
ggccacgcggcatatggctctgcagttgatctccttgacagtaacactaatgttggtgca
acttattttatgacctatcatacaattctgaagaactccacagacttcattgacgccatg
aggaaagcccgtaccatcgcacagaatatcactgataatatggacatcccagggaagaaa
tacaaagtattcccttacagtattttctatgtattttatgagcagtatttaaccattgtg
gatgacaccatcttcaacttgtgcgtgtctctggcagcagtattctttgtgacagtgatc
cttctgggctttgagctctggtcagctgtccttatgtgcatcacgatttctatgatcctt
gttaacatgtttggagtcatgtggctctggggcatcagcttaaatgcagtgtcccttgtc
aatttagtcatgagctgtggcatttcagtagagttctgcagccacgtgaccagagccttt
tcagttagcacaaggggaaaccgggtacaacgtgctgaggatgccctggctcatatgggt
agctcggtgttcagtggtataacactcacaaagtttgttggtatcggtgttcttggcttg
tccaaatctcagatattcaagatcttctacttcagaatgtatctggctatggtgcttctt
ggggcagcacatggcttaatatttctgcctgttctacttagttacttaggcccccaagtg
aataaagcaaaggtgcaagctgcgctgcagagagcccgaggcacagagcaagagcgtctt
tttaaccactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (19)   

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