KEGG   Xenopus tropicalis (tropical clawed frog): 394853
Entry
394853            CDS       T01011                                 
Symbol
mdm2
Name
(RefSeq) E3 ubiquitin-protein ligase Mdm2 isoform 1
  KO
K06643  E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
Organism
xtr  Xenopus tropicalis (tropical clawed frog)
Pathway
xtr04068  FoxO signaling pathway
xtr04110  Cell cycle
xtr04115  p53 signaling pathway
xtr04120  Ubiquitin mediated proteolysis
xtr04144  Endocytosis
xtr04218  Cellular senescence
xtr04625  C-type lectin receptor signaling pathway
Brite
KEGG Orthology (KO) [BR:xtr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    394853 (mdm2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    394853 (mdm2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    394853 (mdm2)
  09143 Cell growth and death
   04110 Cell cycle
    394853 (mdm2)
   04115 p53 signaling pathway
    394853 (mdm2)
   04218 Cellular senescence
    394853 (mdm2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    394853 (mdm2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:xtr04131]
    394853 (mdm2)
   04121 Ubiquitin system [BR:xtr04121]
    394853 (mdm2)
Enzymes [BR:xtr01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     394853 (mdm2)
Membrane trafficking [BR:xtr04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    394853 (mdm2)
Ubiquitin system [BR:xtr04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   MDM2/MDM4 proteins
    394853 (mdm2)
SSDB
Motif
Pfam: zf-C3HC4_3 SWIB zf-RanBP zf-RING_2 zf-FPG_IleRS
Other DBs
NCBI-GeneID: 394853
NCBI-ProteinID: NP_001231689
Xenbase: XB-GENE-482711
UniProt: Q6P3Q9 F7CYT9
Structure
Position
3:complement(58999803..59011771)
AA seq 497 aa
MAEGEGCSQWRQPCNMNLTSTTNCLENSHIMASDQEKLVKPTPLLLSLLKSAGAQKETFT
MKEVIYHLGQYIMAKQLYDEKQQHIVHCSNDPLGELFGVQEFSVKEPRRLYAMISRNLVS
AAVKESSEDVYGNHVCSFPDKQKSQKELLQELPEKVIAPAYDSKPCNSSQRKSNNETVCV
EEISSVDHPAEQQRKRHKSDSISLTFDESLSWWVISGLRCDRNSSESTDTSSNPDPEKHT
VDDNSEQDSDSDQFSVEFEVESVYSDDYSPSGDEHCISEEEEEDEINDEVYQVTIYEAED
SETNAFDVDTEISEADYWKCSECEEINPPLPSHCHRCWALRKDWLPEESKKELHPSKRKR
METEEDEGFDVPDCKKSKLTSSQDTNIDKKEAESIQISESQETEDCSQPSTSGSIASCSQ
EATKEDTRDESMEPSLPLTSVEPCVICQTRPKNGCIVHGRTGHLMACYTCAKKLKKRNKP
CPVCREPIQMIVLTYFS
NT seq 1494 nt   +upstreamnt  +downstreamnt
atggcggagggagagggctgctcgcagtggaggcagccgtgcaatatgaatctcacatcc
actacaaattgcttagaaaattcccacatcatggcttcagatcaagaaaaactggttaag
cccacaccactgttgttatctttgttaaaatctgcaggtgcccaaaaagaaacctttaca
atgaaagaggttatataccatcttggtcagtacataatggccaagcagttgtatgacgag
aagcagcagcatattgtccactgctccaatgatcctcttggagaactatttggtgtacag
gaattttctgtaaaagagccaaggagactatatgcaatgatatctaggaatctggtttca
gcagctgtaaaagagtcatctgaagatgtttatggaaatcatgtgtgcagttttccagac
aagcagaaaagtcagaaggaattacttcaggagctacctgagaaagtaatagcaccagct
tatgactcaaaaccatgcaactcatcccagaggaaaagcaacaatgaaacagtttgtgta
gaagaaatatcttcagttgatcatcctgcagagcaacaaagaaagcgacataagtcagac
agtatttctttaacctttgatgaaagcctttcgtggtgggtgataagtggcttacggtgt
gatagaaatagcagcgaatcgacagacacttcctctaacccagatccagaaaaacacact
gtcgatgacaattctgagcaagattctgattcagatcaatttagcgttgaatttgaagta
gaatctgtgtattcggatgattatagtcctagtggagatgaacattgtatttcagaggag
gaggaggaggatgaaatcaatgatgaggtatatcaggtgactatatacgaggctgaagat
agcgagactaacgcttttgatgttgatactgagatttcagaagctgattattggaagtgc
tcagagtgtgaagagataaatccccctcttccaagtcattgtcatcgatgctgggctctc
cgtaaagactggcttcctgaagaaagcaaaaaagagcttcacccatcaaagagaaaaaga
atggagacagaggaagatgaaggctttgatgtccccgattgtaagaaaagtaaactaaca
agctctcaagacacgaatattgataaaaaagaagctgaaagcatacagatttctgaatcc
caggaaactgaggattgctctcagccttctacatctggcagcattgcttcctgcagtcag
gaggcgaccaaggaagatacaagggatgaaagcatggagcctagtctcccacttaccagc
gttgagccatgtgtcatatgtcagactcgccccaagaatggctgtattgttcatgggaga
acaggtcatctgatggcatgctatacttgtgcaaaaaagctcaagaagaggaacaaacct
tgccctgtgtgcagagagccaatccagatgatcgtgctaacatactttagctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (43)   

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