| C06921 |
Clorazepate; Clorazepic acid |
(P) unclassified |
| C07051 |
Indinavir |
(P) unclassified |
| D00020 |
Tryptophan (USP/INN); L-Tryptophan (JP18) |
(P) unclassified |
| D00076 |
Noradrenaline (JP18); Norepinephrine (INN); Nor adrenalin (TN) |
(P) Target: ADRA2A ADRA2B ADRA2C |
| D00095 |
Epinephrine (USP/INN); Adrenaline (JP18); Adrenalin (TN); Auvi-q (TN); Epipen (TN) |
(CI,P) Target: ADRA2A ADRA2B ADRA2C |
| D00140 |
Erythromycin (JP18/USP/INN); Akne-mycin (TN); Eryc (TN); Erygel (TN); Pce (TN); Staticin (TN); T-stat (TN) |
(P) unclassified |
| D00184 |
Cyclosporine (USP); Ciclosporin (JP18); Gengraf (TN); Neoral (TN); Restasis (TN); Sandimmune (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00211 |
Rifampin (USP); Rifampicin (JP18/INN); Rifadin (TN); Rimactane (TN) |
(P) CYP induction: CYP3A4 |
| D00225 |
Alprazolam (JP18/USP/INN); Xanax (TN) |
(P) unclassified |
| D00252 |
Carbamazepine (JP18/USP/INN); Equetro (TN); Tegretol (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00267 |
Chlordiazepoxide (JP18/USP/INN); Libritabs (TN) |
(P) unclassified |
| D00276 |
Clarithromycin (JP18/USP/INN); Biaxin (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00280 |
Clonazepam (JP18/USP/INN); Klonopin (TN) |
(P) unclassified |
| D00282 |
Clotrimazole (JP18/USP/INN); Lotrimin (TN); Mycelex (TN) |
(P) CYP inhibition: CYP3A4 |
| D00292 |
Dexamethasone (JP18/USP/INN); Decadron (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00293 |
Diazepam (JP18/USP/INN); Diastat (TN); Valium (TN) |
(P) Enzyme: CYP3A4 |
| D00294 |
Diazoxide (JAN/USP/INN); Hyperstat (TN); Proglycem (TN) |
(P) unclassified |
| D00295 |
Cimetidine (JP18/USP/INN); Tagamet (TN) |
(P) CYP inhibition: CYP2D6 CYP3A4 |
| D00311 |
Estazolam (JP18/USP/INN); ProSom (TN) |
(P) unclassified |
| D00322 |
Fluconazole (JP18/USP/INN); Diflucan (TN) |
(P) CYP inhibition: CYP3A4 |
| D00326 |
Fluoxetine (USAN/INN); Fluoxetine (TN) |
(P) Enzyme: CYP2D6 / CYP inhibition: CYP2D6 |
| D00329 |
Flurazepam (JAN/INN); Insumin (TN) |
(P) unclassified |
| D00338 |
Halazepam (USAN/INN); Paxipam (TN) |
(P) unclassified |
| D00346 |
Isoniazid (JP18/USP/INN); Laniazid (TN) |
(CI) unclassified |
| D00350 |
Itraconazole (JP18/USP); Itrizole (TN); Sporanox (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00351 |
Ketoconazole (JP18/USP); Nizoral (TN); Xolegel (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00365 |
Lorazepam (JP18/USP/INN); Ativan (TN) |
(P) unclassified |
| D00370 |
Temazepam (USP/INN); Restoril (TN) |
(P) unclassified |
| D00387 |
Triazolam (JP18/USP/INN); Halcion (TN) |
(P) Enzyme: CYP3A4 |
| D00415 |
Zolmitriptan (JAN/USP/INN); Zomig (TN) |
(P) Enzyme: CYP1A2 |
| D00420 |
Mitotane (JAN/USP/INN); Lysodren (TN) |
(P) unclassified |
| D00435 |
Nevirapine (JAN/USP/INN); Viramune (TN) |
(P) Enzyme: CYP3A4 CYP2D6 |
| D00451 |
Sumatriptan (JAN/USP/INN); Imigran (TN); Imitrex (TN) |
(P) unclassified |
| D00457 |
Quazepam (JAN/USP/INN); Doral (TN) |
(P) Enzyme: CYP3A4 |
| D00464 |
Oxazepam (JAN/USP/INN); Serax (TN) |
(P) unclassified |
| D00470 |
Prazepam (JP18/USAN/INN); Centrax (TN) |
(P) unclassified |
| D00505 |
Phenelzine sulfate (USP); Nardil (TN) |
(CI) unclassified |
| D00506 |
Phenobarbital (JP18/USP/INN); Luminal (TN) |
(P) unclassified |
| D00512 |
Phenytoin (JP18/USP/INN); Dilantin (TN) |
(P) unclassified |
| D00531 |
Nitrazepam (JP18/USAN/INN); Benzalin (TN); Nitrazepam (TN) |
(P) unclassified |
| D00538 |
Zonisamide (JP18/USP/INN); Excegran (TN) |
(P) unclassified |
| D00550 |
Midazolam (JAN/USP/INN); Dormicum (TN); Buccolam (TN); Nayzilam (TN) |
(P) Enzyme: CYP3A4 |
| D00554 |
Ethinyl estradiol (USP); Ethinylestradiol (JP18/INN); Estinyl (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00605 |
Guanabenz acetate (JP18/USP); Wytensin (TN) |
(P) Target: ADRA2A ADRA2B ADRA2C |
| D00619 |
Verapamil hydrochloride (JP18/USP); Calan (TN); Covera-hs (TN); Vasolan (TN); Verelan (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00636 |
Amiodarone hydrochloride (JP18/USP); Ancaron (TN); Cordarone (TN); Nexterone (TN) |
(P) Enzyme: CYP3A4 |
| D00674 |
Naratriptan hydrochloride (JAN/USP); Amerge (TN) |
(P) Enzyme: CYP1A2 CYP2D6 CYP3A4 |
| D00675 |
Rizatriptan benzoate (JAN/USP); Maxalt (TN) |
(P) unclassified |
| D00676 |
Sumatriptan succinate (JAN/USP); Alsuma (TN); Imitrex (TN); Sumave dosepro (TN); Zecutity (TN) |
(P) unclassified |
| D00693 |
Chlordiazepoxide hydrochloride (JAN/USP); Librium (TN) |
(P) unclassified |
| D00694 |
Clorazepate dipotassium (JP18/USP); Tranxene (TN) |
(P) unclassified |
| D00695 |
Flurazepam hydrochloride (USP); Flurazepam dihydrochloride; Dalmane (TN) |
(P) unclassified |
| D00696 |
Midazolam hydrochloride (USAN); Versed (TN) |
(P) Enzyme: CYP3A4 |
| D00697 |
Flumazenil (JAN/USP/INN); Romazicon (TN) |
(P) unclassified |
| D00701 |
Phenobarbital sodium (JAN/USP/INN); Luminal sodium (TN) |
(P) unclassified |
| D00707 |
Fomepizole (JAN/USAN/INN); Antizol (TN) |
(P) CYP inhibition: CYP2D6 CYP1A2 CYP3A4 |
| D00753 |
Sirolimus (JAN/USAN/INN); Rapamune (TN); Rapamycin (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00754 |
Thalidomide (JAN/USP/INN); Thalomid (TN); Thaled (TN) |
(P) unclassified |
| D00780 |
Bromocriptine mesylate (USP); Bromocriptine mesilate (JP18); Parlodel (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00785 |
Selegiline hydrochloride (JAN/USP); Eldepryl (TN) |
(CI) Enzyme: CYP2D6 CYP3A4 |
| D00801 |
Lithium carbonate (JP18/USP); Eskalith (TN); Lithobid (TN) |
(P) unclassified |
| D00822 |
Citalopram hydrobromide (USP); Celexa (TN) |
(P) Enzyme: CYP2D6 CYP3A4 |
| D00823 |
Fluoxetine hydrochloride (JAN/USP); Prozac (TN); Sarafem (TN) |
(P) Enzyme: CYP2D6 / CYP inhibition: CYP2D6 |
| D00824 |
Fluvoxamine maleate (JP18/USP); Luvox (TN) |
(P) Enzyme: CYP2D6 / CYP inhibition: CYP1A2 CYP2D6 CYP3A4 |
| D00825 |
Sertraline hydrochloride (JAN/USP); Zoloft (TN) |
(P) Enzyme: CYP3A4 |
| D00826 |
Tranylcypromine sulfate (USP); Parnate (TN) |
(CI) unclassified |
| D00831 |
Mefloquine hydrochloride (JP18/USP); Lariam (TN) |
(P) unclassified |
| D00851 |
Erythromycin estolate (USP); Erythromycin estorate (JAN); Ilosone (TN) |
(P) unclassified |
| D00854 |
Quinupristin and dalfopristin; Synercid (TN) |
(P) CYP inhibition: CYP3A4 |
| D00879 |
Rifapentine (USAN/INN); Priftin (TN) |
(P) CYP induction: CYP3A4 |
| D00896 |
Efavirenz (JAN/USP/INN); Sustiva (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00897 |
Indinavir sulfate (USP); Crixivan (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00899 |
Nelfinavir mesylate (USAN/INN); Nelfinavir mesilate (JAN); Viracept (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00947 |
Linezolid (JAN/USAN/INN); Zyvox (TN) |
(P) unclassified |
| D00960 |
Anastrozole (JP18/USP/INN); Arimidex (TN) |
(P) CYP inhibition: CYP1A2 CYP3A4 |
| D00961 |
Bicalutamide (JP18/USP/INN); Casodex (TN) |
(P) CYP inhibition: CYP3A4 |
| D00975 |
Dexamethasone sodium phosphate (JAN/USP); Dalalone (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01097 |
Lazabemide hydrochloride (JAN/USAN); Tempium (TN) |
(CI) unclassified |
| D01227 |
Bosentan (USAN); Bosentan hydrate (JAN); Tracleer (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01230 |
Flunitrazepam (JP18/USAN/INN); Rohypnol (TN) |
(P) unclassified |
| D01235 |
Josamycin (JP18/USAN/INN); Leucomycin A3; JM; Josamycin (TN) |
(P) CYP inhibition: CYP3A4 |
| D01245 |
Bromazepam (JP18/USAN/INN); Lectopam (TN) |
(P) unclassified |
| D01253 |
Clobazam (JAN/USAN/INN); Mystan (TN); Onfi (TN) |
(P) Enzyme: CYP3A4 |
| D01254 |
Tofisopam (JP18/INN); Emandaxin (TN) |
(P) unclassified |
| D01268 |
Cloxazolam (JP18/INN); Sepazon (TN) |
(P) unclassified |
| D01276 |
Atazanavir sulfate (JAN/USAN); Reyataz (TN) |
(P) CYP inhibition: CYP3A4 |
| D01278 |
Oxazolam (JP18/INN); Serenal (TN) |
(P) unclassified |
| D01279 |
Flutoprazepam (JP18/INN); Restas (TN) |
(P) unclassified |
| D01280 |
Warfarin potassium (JP18); Athrombin-K (TN) |
(P) unclassified |
| D01286 |
Flutazolam (JAN/INN); Coreminal (TN) |
(P) unclassified |
| D01292 |
Medazepam (JP18/INN); Pamnace (TN) |
(P) unclassified |
| D01293 |
Ethyl loflazepate (JP18/INN); Meilax (TN) |
(P) Enzyme: CYP3A4 |
| D01316 |
Mexazolam (JAN/INN); Melex (TN) |
(P) Enzyme: CYP3A4 |
| D01322 |
Troleandomycin (USAN/INN); Triacetyloleandomycin (JAN); TAO; Tao (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D01328 |
Clotiazepam (JP18/INN); Rize (TN) |
(P) unclassified |
| D01339 |
Midecamycin (JP18/INN); Medemycin (TN) |
(P) CYP inhibition: CYP3A4 |
| D01354 |
Fludiazepam (JP18/INN); Erispan (TN) |
(P) unclassified |
| D01355 |
Tramadol hydrochloride (JP18/USP); Ultram (TN) |
(P) Enzyme: CYP2D6 CYP3A4 |
| D01361 |
Erythromycin ethylsuccinate (JP18/USP); E.E.S. (TN); Eryped (TN); Erythrocin W (TN) |
(P) unclassified |
| D01408 |
Flurazepam hydrochloride (JP18); Flurazepam monohydrochloride; Dalmate (TN) |
(P) unclassified |
| D01429 |
Fosfluconazole (JAN/INN); Prodif (TN) |
(P) CYP inhibition: CYP3A4 |
| D01501 |
Isoniazid calcium pyruvinate (JAN); Pyruvic acid calcium isoniazid |
(CI) unclassified |
| D01510 |
Dexamethasone metasulfobenzoate sodium (JAN); Dexamethazone metasulfobenzoate sodium; Dexapos; Santeson (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01514 |
Etizolam (JP18/INN); Sedekopan (TN) |
(P) Enzyme: CYP3A4 |
| D01564 |
Rilmazafone hydrochloride hydrate (JP18); Rilmazafone hydrochloride dihydrate; Rilmazafone hydrochloride; Rhythmy (TN) |
(P) Enzyme: CYP3A4 |
| D01593 |
Nimetazepam (JAN/INN); Erimin (TN) |
(P) unclassified |
| D01615 |
Dexamethasone palmitate (JAN); Dexamethasone 21-palmitate; Limethason (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01632 |
Dexamethasone dipropionate (USAN); Dexamethasone propionate (JAN); Hifmeta (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01636 |
Midecamycin acetate (JP18); Miocamycin; Miocamycin (TN) |
(P) CYP inhibition: CYP3A4 |
| D01657 |
Lormetazepam (JAN/USAN/INN); Loramet (TN) |
(P) unclassified |
| D01744 |
Brotizolam (JP18/USAN/INN); Lendormin (TN) |
(P) Enzyme: CYP3A4 |
| D01758 |
Haloxazolam (JP18/INN); Somelin (TN) |
(P) unclassified |
| D01832 |
Modafinil (JAN/USP/INN); Provigil (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP1A2 CYP3A4 |
| D01856 |
Nifekalant hydrochloride (JAN); MS 551; Shinbit (TN) |
(P) unclassified |
| D01888 |
Safrazine hydrochloride (JAN) |
(CI) unclassified |
| D01948 |
Dexamethasone valerate (JAN); Dexamethasone 17-valerate; DV-17; Voalla ointment (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01973 |
Eletriptan hydrobromide (JAN/USAN); Relpax (TN) |
(P) Enzyme: CYP3A4 |
| D01980 |
Luliconazole (JAN/USAN/INN); Lulicon (TN); Luzu (TN) |
(P) CYP inhibition: CYP3A4 |
| D02002 |
Isoniazid sodium methanesulfonate hydrate (JAN); Isoniazid sodium methanesulfonate monohydrate; Isoniazid sodium methanesulfonate; IHMS; Neoiscotin (TN) |
(CI) unclassified |
| D02004 |
Apomorphine hydrochloride (USP); Apomorphine hydrochloride hydrate (JAN); Apokyn (TN); Ixense (TN); Uprima (TN) |
(P) unclassified |
| D02008 |
Tadalafil (JAN/USP/INN); Adcirca (TN); Cialis (TN); Zalutia (TN) |
(P) Enzyme: CYP3A4 |
| D02009 |
Erythromycin lactobionate (JP18/USP); Erythrocin (TN) |
(P) unclassified |
| D02069 |
Atropine sulfate (JP18/USP); Isopto Atropine (TN) |
(P) unclassified |
| D02096 |
Fosphenytoin sodium (USP); Cerebyx (TN); Sesquient (TN) |
(P) CYP induction: CYP3A4 |
| D02102 |
Methadone hydrochloride (JAN/USP); Dolophine hydrochloride (TN) |
(P) Enzyme: CYP2D6 CYP3A4 / CYP induction: CYP3A4 |
| D02103 |
Phenytoin sodium (USP); Phenytoin sodium for injection (JP18); Aleviatin (TN); Dilantin (TN) |
(P) unclassified |
| D02106 |
Arsenic trioxide (JP18/USAN); Trisenox (TN) |
(P) unclassified |
| D02174 |
Dexamethasone acetate (JAN/USP); Decadronal (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02184 |
Erythromycin stearate (JP18/USP); Bristamycin (TN) |
(P) unclassified |
| D02229 |
Sildenafil citrate (JAN/USP); Revatio (TN); Viagra (TN) |
(P) Enzyme: CYP3A4 |
| D02260 |
Paroxetine hydrochloride hemihydrate (USP); Paroxetine hydrochloride hydrate (JP18); Paxil (TN) |
(P) Enzyme: CYP2D6 / CYP inhibition: CYP2D6 |
| D02356 |
Verapamil (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02360 |
Sertraline (INN) |
(P) Enzyme: CYP3A4 |
| D02362 |
Paroxetine (USP/INN); Paroxetine (TN) |
(P) Enzyme: CYP2D6 / CYP inhibition: CYP2D6 |
| D02372 |
Perospirone hydrochloride hydrate (JAN); Lullan (TN) |
(P) Target: HTR2A |
| D02484 |
Artemether and lumefantrine; Coartem (TN) |
(P) unclassified |
| D02497 |
Fosamprenavir (INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02523 |
Erythromycin acistrate (USAN); Erasis (TN) |
(P) unclassified |
| D02524 |
Erythromycin gluceptate (USP); Erythromycin glucoheptonate; Ilotycin gluceptate (TN) |
(P) unclassified |
| D02525 |
Erythromycin propionate (USAN) |
(P) unclassified |
| D02554 |
Rifaximin (JAN/USAN/INN); Xifaxan (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02555 |
Posaconazole (JAN/USAN/INN); Noxafil (TN) |
(P) CYP inhibition: CYP3A4 |
| D02559 |
Toloxatone (INN); Humoryl (TN) |
(CI) unclassified |
| D02560 |
Brofaromine (INN); Consonar (TN) |
(CI) unclassified |
| D02561 |
Moclobemide (USAN/INN); Aurorix (TN) |
(CI) CYP inhibition: CYP2D6 |
| D02562 |
Rasagiline mesylate (USAN); Rasagiline mesilate (JAN); Azilect (TN) |
(CI) Enzyme: CYP1A2 |
| D02563 |
Befloxatone (INN) |
(CI) unclassified |
| D02564 |
Pargyline hydrochloride (USAN); Eutonyl (TN) |
(CI) unclassified |
| D02567 |
Escitalopram oxalate (JAN/USP); Lexapro (TN) |
(P) Enzyme: CYP2D6 CYP3A4 / CYP inhibition: CYP2D6 |
| D02579 |
Iproniazid (INN) |
(CI) unclassified |
| D02580 |
Isocarboxazid (INN); Marplan (TN) |
(CI) unclassified |
| D02581 |
Cimoxatone (INN) |
(CI) unclassified |
| D02591 |
Dexamethasone acefurate (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02592 |
Dexamethasone beloxil (USAN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02600 |
Demoxepam (USAN/INN) |
(P) unclassified |
| D02691 |
Somatropin (USP/INN); Somatropin (genetical recombination) (JAN); Human growth hormone (JAN); Asellacrin (TN); Humatrope (TN); Nutropin (TN); Omnitrope (TN) |
(P) unclassified |
| D02732 |
Pranlukast hydrate (JP18); Onon (TN) |
(P) Enzyme: CYP3A4 |
| D02770 |
Adinazolam (USAN/INN) |
(P) unclassified |
| D02771 |
Adinazolam mesylate (USAN) |
(P) unclassified |
| D02787 |
Alaproclate (USAN/INN) |
(P) unclassified |
| D02824 |
Almotriptan (USAN) |
(P) Enzyme: CYP2D6 CYP3A4 |
| D02825 |
Almotriptan malate (USP); Axert (TN) |
(P) Enzyme: CYP2D6 CYP3A4 |
| D02861 |
Indinavir sulfate ethanolate (JAN); Crixivan (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02867 |
Fosamprenavir calcium hydrate (JAN); Lexiva (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02968 |
Aprepitant (JAN/USP/INN); Aponvie (TN); Emend (TN); Cinvanti (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D03014 |
Avitriptan fumarate (USAN) |
(P) unclassified |
| D03083 |
Bentazepam (USAN/INN) |
(P) unclassified |
| D03098 |
Berythromycin (USAN/INN); Erythromycin B |
(P) unclassified |
| D03106 |
Bexarotene (JAN/USAN/INN); Targretin (TN) |
(P) unclassified |
| D03165 |
Bromocriptine (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03239 |
Ladostigil tartrate (USAN) |
(CI) unclassified |
| D03248 |
Clorgiline (INN); Clorgyline |
(CI) unclassified |
| D03260 |
Vardenafil hydrochloride hydrate (JAN); Vardenafil monohydrochloride trihydrate; Levitra (TN); Staxyn (TN) |
(P) Enzyme: CYP3A4 |
| D03365 |
Nicotine (USP); Habitrol (TN) |
(P) CYP induction: CYP1A2 |
| D03409 |
Caroxazone (USAN/INN) |
(CI) unclassified |
| D03503 |
Cimetidine hydrochloride (USP); Cimetidine hydrochloride (TN) |
(P) CYP inhibition: CYP2D6 CYP3A4 |
| D03562 |
Clorazepate monopotassium (USAN) |
(P) unclassified |
| D03631 |
Cyprazepam (USAN/INN) |
(P) unclassified |
| D03649 |
Dapoxetine hydrochloride (USAN) |
(P) unclassified |
| D03656 |
Darunavir (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03658 |
Dasatinib (JAN/INN) |
(P) Enzyme: CYP3A4 |
| D03669 |
Deferasirox (JAN/USAN/INN); Exjade (TN); Jadenu (TN) |
(P) CYP inhibition: CYP1A2 / CYP induction: CYP3A4 |
| D03731 |
Selegiline (USAN/INN); Emsam (TN) |
(CI) Enzyme: CYP2D6 CYP3A4 |
| D03733 |
Mofegiline hydrochloride (USAN) |
(CI) unclassified |
| D03737 |
Dextofisopam (USAN/INN) |
(P) unclassified |
| D03833 |
Indinavir (USAN); Indinavir hydrate |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03835 |
Fosamprenavir calcium (USAN); Lexiva (TN); Telzir (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03837 |
Fosamprenavir sodium (USAN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D04024 |
Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN); Lapatinib ditosylate monohydrate; Tykerb (TN); Tyverb (TN) |
(P) Enzyme: CYP3A4 |
| D04052 |
Epinephrine and lidocaine hydrochloride; Adrenaline and lidocaine hydrochloride; Xylocaine (TN) |
(CI,P) Enzyme: CYP1A2 CYP3A4 |
| D04054 |
Erythromycin salnacedin (USAN); Erythromycin salnacedin dihydrate |
(P) unclassified |
| D04081 |
Tropicamide and phenylephrine hydrochloride; Sandol P (TN) |
(P) unclassified |
| D04092 |
Etryptamine acetate (USAN) |
(CI) unclassified |
| D04105 |
Etoperidone hydrochloride (USAN); Etonin (TN) |
(P) unclassified |
| D04112 |
Etravirine (JAN/USAN/INN); Intelence (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D04248 |
Fosazepam (USAN/INN) |
(P) unclassified |
| D04264 |
Frovatriptan succinate (USAN); Frovatriptan succinate hydrate; Frova (TN) |
(P) unclassified |
| D04641 |
Istradefylline (JAN/USAN/INN); Nourianz (TN); Nouriast (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D04650 |
Ketazolam (USAN/INN) |
(P) unclassified |
| D04666 |
Lanreotide acetate (JAN/USAN); Somatuline (TN) |
(P) unclassified |
| D04681 |
Lazabemide (USAN/INN) |
(CI) unclassified |
| D04721 |
Levotofisopam (USAN/INN) |
(P) unclassified |
| D04813 |
Lidocaine hydrochloride and epinephrine bitartrate; Lidocaine hydrochloride and adrenaline bitartrate; Ora (TN); Lidosite (TN) |
(P) Enzyme: CYP1A2 CYP3A4 |
| D04882 |
Medazepam hydrochloride (USAN); Nobrium (TN) |
(P) unclassified |
| D05028 |
Midazolam maleate (USAN) |
(P) Enzyme: CYP3A4 |
| D05033 |
Milacemide hydrochloride (USAN) |
(CI) unclassified |
| D05039 |
Minaprine (USAN/INN); Cantor (TN) |
(CI) Enzyme: CYP2D6 |
| D05040 |
Minaprine hydrochloride (USAN) |
(CI) Enzyme: CYP2D6 |
| D05351 |
Josamycin propionate (JP18); Josamy (TN) |
(P) CYP inhibition: CYP3A4 |
| D05374 |
Paroxetine hydrochloride (USP); Paxil (TN) |
(P) Enzyme: CYP2D6 / CYP inhibition: CYP2D6 |
| D05375 |
Paroxetine mesylate (USAN); Brisdelle (TN); Pexeva (TN) |
(P) Enzyme: CYP2D6 / CYP inhibition: CYP2D6 |
| D05491 |
Pirandamine hydrochloride (USAN) |
(P) unclassified |
| D05710 |
Reclazepam (USAN/INN) |
(P) unclassified |
| D05740 |
Rizatriptan sulfate (USAN) |
(P) unclassified |
| D05775 |
Rufinamide (JAN/USP/INN); Banzel (TN) |
(P) unclassified |
| D05928 |
Stiripentol (JAN/USAN/INN); Diacomit (TN) |
(P) Enzyme: CYP1A2 CYP3A4 / CYP inhibition: CYP1A2 CYP3A4 CYP2D6 |
| D05942 |
Sulazepam (USAN/INN) |
(P) unclassified |
| D06231 |
Triflubazam (USAN/INN) |
(P) unclassified |
| D06367 |
Zimeldine hydrochloride (USAN); Zimeldine hydrochloride hydrate |
(P) unclassified |
| D06405 |
Nalfurafine hydrochloride (JAN/USAN) |
(P) Enzyme: CYP3A4 |
| D06413 |
Nilotinib hydrochloride hydrate (JAN); Nilotinib monohydrochloride monohydrate; Tasigna (TN) |
(P) Enzyme: CYP3A4 |
| D06414 |
Dasatinib (USAN); Dasatinib hydrate (JAN); Sprycel (TN) |
(P) Enzyme: CYP3A4 |
| D06478 |
Darunavir ethanolate (JAN); Prezista (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D06597 |
Fosaprepitant dimeglumine (USAN); Fosaprepitant meglumine (JAN); Proemend (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D07073 |
Dexamethasone cipecilate (JAN/INN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07314 |
Pinazepam (INN); Domar (TN) |
(P) unclassified |
| D07315 |
Camazepam (INN) |
(P) unclassified |
| D07326 |
Loprazolam (INN); Dormonoct (TN) |
(P) unclassified |
| D07327 |
Doxefazepam (INN) |
(P) unclassified |
| D07328 |
Cinolazepam (INN); Gerodorm (TN) |
(P) unclassified |
| D07337 |
Nialamide (INN); Niamid (TN) |
(CI) unclassified |
| D07338 |
Iproclozide (INN); Iproclozide (TN) |
(CI) unclassified |
| D07471 |
Atazanavir (INN); Reyataz (TN) |
(P) CYP inhibition: CYP3A4 |
| D07538 |
Bosentan (INN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07583 |
Phenytoin and phenobarbital; Aleviatin with phenobarbital (TN) |
(P) unclassified |
| D07595 |
Fosphenytoin sodium hydrate (JAN); Fostoin (TN) |
(P) CYP induction: CYP3A4 |
| D07704 |
Citalopram (USP/INN); Citadur (TN) |
(P) Enzyme: CYP2D6 CYP3A4 |
| D07705 |
Citalopram hydrochloride; Seropram (TN) |
(P) Enzyme: CYP2D6 CYP3A4 |
| D07710 |
Clarithromycin lactobionate; Klacid (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D07714 |
Climazolam (INN); Climasol [veterinary] (TN) |
(P) unclassified |
| D07784 |
Delorazepam (INN); Dadumir (TN) |
(P) unclassified |
| D07796 |
Dexamethasone 21-acetate; Dexamethasone acetate anhydrous; Decaject-L.A. (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07797 |
Dexamethasone isonicotinate; Dexamethasone 21-isonicotinate; Voren [veterinary] (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07798 |
Dexamethasone sodium hemisulfate; Dexamethasone 21-sodium sulfate; Colircusi Dexametasona (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07799 |
Dexamethasone 21-tebutate; Dexamethasone tertiary butyl acetate; Dexamedium [veterinary] (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07800 |
Dexamethasone 21-valerate; Voalla (TN); Zalucs (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07801 |
Dexamethasone phenylpropionate; Dexafort [veterinary] (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07802 |
Dexamethasone phosphate; Decadron-phosphate (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07887 |
Eletriptan (INN) |
(P) Enzyme: CYP3A4 |
| D07909 |
Erythromycin thiocyanate; Erythrocin (TN) |
(P) unclassified |
| D07910 |
Erythromycin stinoprate (INN); Erysec (TN) |
(P) unclassified |
| D07913 |
Escitalopram (INN); Esertia (TN) |
(P) Enzyme: CYP2D6 CYP3A4 / CYP inhibition: CYP2D6 |
| D07928 |
Ethinylestradiol propanesulfonate; Turisteron (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D07984 |
Fluvoxamine (INN) |
(P) Enzyme: CYP2D6 / CYP inhibition: CYP1A2 CYP2D6 CYP3A4 |
| D07993 |
Fosphenytoin (INN) |
(P) CYP induction: CYP3A4 |
| D07997 |
Frovatriptan (INN); Allergo filmtabletten (TN) |
(P) unclassified |
| D08085 |
Iproniazid phosphate; Marsilid (TN) |
(CI) unclassified |
| D08145 |
Loprazolam mesilate; Loprazolam mesylate; Loprazolam methanesulfonate; Havlane (TN) |
(P) unclassified |
| D08195 |
Methadone (BAN) |
(P) Enzyme: CYP2D6 CYP3A4 / CYP induction: CYP3A4 |
| D08255 |
Naratriptan (INN); Naramig (TN) |
(P) Enzyme: CYP1A2 CYP2D6 CYP3A4 |
| D08259 |
Nelfinavir (INN); Viracept (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D08283 |
Nordazepam (INN); Calmday (TN) |
(P) Enzyme: CYP3A4 |
| D08349 |
Phenelzine (BAN) |
(CI) unclassified |
| D08392 |
Pirlindole (INN); Pyrazidol (TN) |
(CI) unclassified |
| D08393 |
Pirlindole hydrochloride; Implementor (TN) |
(CI) unclassified |
| D08453 |
Pargyline (INN) |
(CI) unclassified |
| D08469 |
Rasagiline (USAN/INN); Azilect (TN) |
(CI) Enzyme: CYP1A2 |
| D08479 |
Rifampicin sodium; Rifadine (TN) |
(P) CYP induction: CYP3A4 |
| D08481 |
Rilmazafone (INN) |
(P) Enzyme: CYP3A4 |
| D08485 |
Rizatriptan (INN); Maxalt (TN) |
(P) unclassified |
| D08616 |
Teneligliptin (INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 CYP3A4 |
| D08625 |
Tranylcypromine (INN); Parnate (TN) |
(CI) unclassified |
| D08774 |
Amoxicillin hydrate, clarithromycin and lansoprazole; Lansap (TN); Prevpac (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D08837 |
Aclidinium bromide (JAN/USAN/INN); Tudorza pressair (TN); Eklira genuair (TN) |
(P) CYP inhibition: CYP2D6 CYP3A4 |
| D09012 |
Telaprevir (JAN/USAN/INN); Incivek (TN); Incivo (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D09215 |
Eslicarbazepine (USAN/INN) |
(P) CYP induction: CYP3A4 |
| D09394 |
Fidaxomicin (JAN/USAN); Dificid (TN); Dificlir (TN) |
(P) CYP inhibition: CYP3A4 |
| D09535 |
Mirabegron (JAN/USAN/INN); Myrbetriq (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D09612 |
Eslicarbazepine acetate (USAN); Zebinix (TN); Aptiom (TN) |
(P) CYP induction: CYP3A4 |
| D09638 |
Lomitapide mesylate (USAN); Lomitapide mesilate (JAN); Juxtapid (TN); Lojuxta (TN) |
(P) Enzyme: CYP3A4 |
| D09701 |
Abiraterone acetate (JAN/USP); Zytiga (TN) |
(P) Enzyme: CYP3A4 |
| D09731 |
Crizotinib (JAN/USAN/INN); Xalkori (TN) |
(P) Enzyme: CYP3A4 |
| D09756 |
Teneligliptin hydrobromide hydrate (JAN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 CYP3A4 |
| D09773 |
Isoniazid glucuronate sodium (JAN) |
(CI) unclassified |
| D09799 |
Carotegrast methyl (JAN); Carogra (TN) |
(P) CYP inhibition: CYP3A4 |
| D09894 |
Eliglustat tartrate (JAN/USAN); Eliglustat hemitartrate; Cerdelga (TN) |
(P) Enzyme: CYP2D6 |
| D09996 |
Vemurafenib (JAN/USAN/INN); Zelboraf (TN) |
(P) CYP inhibition: CYP1A2 / CYP induction: CYP3A4 |
| D10003 |
Hemin (JAN); Normosang (TN); Panhematin (TN) |
(P) CYP induction: CYP3A4 CYP2D6 |
| D10064 |
Dabrafenib (USAN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10093 |
Asunaprevir (JAN/USAN); Sunvepra (TN) |
(P) CYP inhibition: CYP2D6 / CYP induction: CYP3A4 |
| D10104 |
Dabrafenib mesylate (USAN); Dabrafenib mesilate (JAN); Tafinlar (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10158 |
Safinamide (USAN/INN) |
(CI) unclassified |
| D10161 |
Sarilumab (USAN); Sarilumab (genetical receombination) (JAN); Kevzara (TN) |
(P) unclassified |
| D10191 |
Safinamide mesylate (USAN); Safinamide mesilate (JAN); Safinamide methanesulfonate; Xadago (TN); Equfina (TN) |
(CI) unclassified |
| D10218 |
Enzalutamide (JAN/USAN); Xtandi (TN) |
(P) unclassified |
| D10246 |
Omeprazole, clarithromycin and amoxicillin; Omeclamox-pak (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D10372 |
Palbociclib (JAN/USAN); Ibrance (TN) |
(P) unclassified |
| D10466 |
Vonoprazan fumarate (JAN/USAN); Takecab (TN); Voquezna (TN) |
(P) Enzyme: CYP2D6 CYP3A4 |
| D10514 |
Dacomitinib (USAN); Dacomitinib hydrate (JAN); Vizimpro (TN) |
(P) CYP inhibition: CYP2D6 |
| D10519 |
Rabeprazole, amoxicillin and clarithromycin; Rabecure (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D10537 |
Methylthioninium chloride hydrate (JAN); Methylene blue (TN) |
(P) CYP inhibition: CYP1A2 |
| D10551 |
Ceritinib (JAN/USAN/INN); Zykadia (TN) |
(P) unclassified |
| D10564 |
Amenamevir (JAN/INN); Amenalief (TN) |
(P) unclassified |
| D10566 |
Pasireotide pamoate (JAN); Signifor lar (TN) |
(P) unclassified |
| D10582 |
Dasabuvir, ombitasvir, paritaprevir and ritonavir; Viekira pak (TN) |
(P) CYP inhibition: CYP3A4 |
| D10643 |
Isavuconazonium sulfate (JAN/USAN); Cresemba (TN) |
(P) unclassified |
| D10745 |
Ombitasvir, paritaprevir and ritonavir; Technivie (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D10762 |
Fosravuconazole L-lysine ethanolate (JAN) |
(P) unclassified |
| D10774 |
Vonoprazan, amoxicillin and metronidazole; Vonopion (TN) |
(P) Enzyme: CYP2D6 CYP3A4 |
| D10775 |
Vonoprazan, amoxicillin and clarithromycin; Vonosap (TN); Voquenza (TN) |
(P) Enzyme: CYP2D6 CYP3A4 / CYP inhibition: CYP3A4 |
| D10801 |
Letermovir (JAN/USAN/INN); Prevymis (TN) |
(P) unclassified |
| D10825 |
Opicapone (JAN/USAN/INN); Ongentys (TN) |
(P) unclassified |
| D10829 |
Rasagiline tartrate; Rasagiline (TN) |
(CI) Enzyme: CYP1A2 |
| D10882 |
Daclatasvir, asunaprevir and beclabuvir; Ximency (TN) |
(P) CYP induction: CYP3A4 |
| D10891 |
Capmatinib hydrochloride (USAN); Capmatinib hydrochloride hydrate (JAN); Tabrecta (TN) |
(P) Enzyme: CYP3A4 |
| D10895 |
Fosaprepitant (INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D10926 |
Entrectinib (JAN/USAN/INN); Rozlytrek (TN) |
(P) Enzyme: CYP3A4 |
| D10990 |
Somatrogon (USAN/INN); Somatrogon (genetical recombination) (JAN); Somatrogon-ghla; Ngenla (TN) |
(P) unclassified |
| D11012 |
Lorlatinib (JAN/USAN/INN); Lorbrena (TN) |
(P) unclassified |
| D11027 |
Ropeginterferon alfa-2b (INN); Ropeginterferon alfa-2b (genetical recombination) (JAN); Ropeginterferon alfa-2b-njft; Besremi (TN) |
(P) unclassified |
| D11040 |
Apalutamide (JAN/INN); Erleada (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11062 |
Osilodrostat phosphate (JAN/USAN); Isturisa (TN) |
(P) Enzyme: CYP2D6 CYP3A4 |
| D11138 |
Larotrectinib sulfate (JAN/USAN); Vitrakvi (TN) |
(P) unclassified |
| D11194 |
Somapacitan (USAN/INN); Somapacitan (genetical recombination) (JAN); Somapacitan-beco; Sogroya (TN) |
(P) unclassified |
| D11370 |
Fosnetupitant chloride hydrochloride (JAN/USAN); Arokaris (TN) |
(P) unclassified |
| D11485 |
Tazemetostat hydrobromide (JAN/USAN); Tazverik (TN) |
(P) unclassified |
| D11617 |
Eletriptan hydrobromide monohydrate |
(P) Enzyme: CYP3A4 |
| D11673 |
Berotralstat (USAN/INN) |
(P) CYP inhibition: CYP2D6 CYP3A4 |
| D11674 |
Berotralstat hydrochloride (JAN/USAN); Orladeyo (TN) |
(P) CYP inhibition: CYP2D6 CYP3A4 |
| D11708 |
Givosiran sodium (JAN); Givlaari (TN) |
(P) unclassified |
| D11713 |
Selpercatinib (JAN/USAN/INN); Retevmo (TN) |
(P) Enzyme: CYP3A4 |
| D11804 |
Aspirin and vonoprazan; Cabpirin (TN) |
(P) unclassified |
| D11920 |
Pimitespib (JAN); Jeselhy (TN) |
(P) unclassified |
| D11968 |
Teneligliptin hydrobromide (JAN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 CYP3A4 |
| D11970 |
Ritlecitinib tosylate (USAN); Ritlecitinib tosilate (JAN); Litfulo (TN) |
(P) CYP inhibition: CYP1A2 |
| D12015 |
St. John's wort; SJW |
(P) unclassified |
| D12055 |
Sotorasib (JAN/USAN); Lumakras (TN) |
(P) unclassified |
| D12586 |
Mifepristone and misoprostol; Mefeego (TN) |
(P) unclassified |
| D12637 |
Darunavir hydrate |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D12752 |
Darunavir propylene glycolate |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
