PCIDB

KNApSAcK Metabolite C00001126

Metabolite

KNApSAcK Entry

id C00001126
Name alpha-D-Mannose / alpha-D-Mannopyranose
CAS RN 7296-15-3
Standard InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2?,3-,4+,5?,6+/m1/s1
Standard InChI (Main Layer) InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2

Cluster

Phytochemical cluster
KCF-S cluster No. 1283

Link

ChEMBL

By standard InChI CHEMBL98182
By standard InChI Main Layer CHEMBL300520 CHEMBL98182 CHEMBL103010 CHEMBL423707 CHEMBL195923 CHEMBL469448 CHEMBL1222152 CHEMBL1222250 CHEMBL1233058 CHEMBL1453070 CHEMBL1519430 CHEMBL1614854 CHEMBL1873035 CHEMBL2093058 CHEMBL2115552

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Brassicaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae

Human Protein / Gene in interaction

26 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P11217 Glycogen phosphorylase, muscle form Enzyme CHEMBL1222250 CHEMBL680567 (1)
1 / 1
P10323 Acrosin S1A CHEMBL300520 CHEMBL469448 CHEMBL1222250 CHEMBL1233058 CHEMBL1873035 CHEMBL2093058 CHEMBL639052 (6) CHEMBL639054 (1)
CHEMBL639764 (1)
0 / 0
Q9NNX6 CD209 antigen Unclassified protein CHEMBL469448 CHEMBL2185436 (1)
2 / 0
P11226 Mannose-binding protein C Unclassified protein CHEMBL469448 CHEMBL2185437 (1)
2 / 2
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL1453070 CHEMBL1613776 (1)
3 / 1
P09382 Galectin-1 Other cytosolic protein CHEMBL300520 CHEMBL1233058 CHEMBL867750 (1) CHEMBL901484 (1)
CHEMBL1005625 (1) CHEMBL1008162 (1)
0 / 0
P11216 Glycogen phosphorylase, brain form Enzyme CHEMBL98182 CHEMBL103010 CHEMBL1222250 CHEMBL680565 (1) CHEMBL680572 (2)
CHEMBL680573 (1) CHEMBL680574 (2)
CHEMBL749044 (2)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL195923 CHEMBL1233058 CHEMBL1738606 (2)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL1222250 CHEMBL844641 (1)
0 / 0
P07306 Asialoglycoprotein receptor 1 Membrane receptor CHEMBL300520 CHEMBL1614854 CHEMBL1042964 (2) CHEMBL1042965 (2)
CHEMBL1042966 (2) CHEMBL1042967 (2)
0 / 0
P11308 Transcriptional regulator ERG Unclassified protein CHEMBL469448 CHEMBL2114924 (1)
1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL195923 CHEMBL469448 CHEMBL1794401 (2)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL195923 CHEMBL1614211 (1)
0 / 0
Q6P4F1 Alpha-(1,3)-fucosyltransferase 10 Enzyme CHEMBL195923 CHEMBL1222250 CHEMBL1873035 CHEMBL2115552 CHEMBL681260 (4)
0 / 0
P17931 Galectin-3 Other cytosolic protein CHEMBL300520 CHEMBL1233058 CHEMBL867751 (1) CHEMBL902488 (1)
CHEMBL1008161 (1) CHEMBL1008163 (1)
0 / 1
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL195923 CHEMBL469448 CHEMBL1222250 CHEMBL1873035 CHEMBL1794536 (4)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL1519430 CHEMBL1614364 (1)
1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL195923 CHEMBL2354311 (1)
1 / 0
O00255 Menin Unclassified protein CHEMBL1519430 CHEMBL1614531 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL1519430 CHEMBL1614531 (1)
1 / 3
Q9UJ71 C-type lectin domain family 4 member K Unclassified protein CHEMBL469448 CHEMBL2185432 (1)
1 / 0
P22897 Macrophage mannose receptor 1 Unclassified protein CHEMBL469448 CHEMBL2185434 (1)
0 / 0
Q8WTT0 C-type lectin domain family 4 member C Unclassified protein CHEMBL469448 CHEMBL2185430 (1)
0 / 0
Q6EIG7 C-type lectin domain family 6 member A Unclassified protein CHEMBL469448 CHEMBL2185431 (1)
0 / 0
P35247 Pulmonary surfactant-associated protein D Unclassified protein CHEMBL469448 CHEMBL2185433 (1)
0 / 0
Q9H2X3 C-type lectin domain family 4 member M Unclassified protein CHEMBL469448 CHEMBL2185435 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#613393 Birbeck granule deficiency Q9UJ71
#614371 Dengue virus, susceptibility to Q9NNX6
#612219 Ewing sarcoma; es P11308
#137800 Glioma susceptibility 1; glm1 O75874
#232600 Glycogen storage disease v P11217
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610424 Hepatitis b virus, susceptibility to P11226
#145000 Hyperparathyroidism 1; hrpt1 O00255
#614372 Mannose-binding protein deficiency P11226
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to Q9NNX6
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (15)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00069 Glycogen storage diseases (GSD) P11217 (related)
H00105 Mannose-binding lectin pathway component defects P11226 (related)
H00342 Tuberculosis P11226 (related)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H00032 Thyroid cancer P17931 (marker)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)