PCIDB

KNApSAcK Metabolite C00001393

Metabolite

KNApSAcK Entry

id C00001393
Name L-Serine
CAS RN 56-45-1
Standard InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
Standard InChI (Main Layer) InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)

Cluster

Phytochemical cluster
KCF-S cluster No. 3420

Link

ChEMBL

By standard InChI CHEMBL11298
By standard InChI Main Layer CHEMBL11298 CHEMBL285123

KEGG

By LinkDB C00065

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Brassicaceae 1
Enterobacteriaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Escherichia coli 562 Enterobacteriaceae Bacteria

Human Protein / Gene in interaction

13 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL11298 CHEMBL1741321 (3)
1 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL285123 CHEMBL1794499 (1)
2 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) CHEMBL285123 CHEMBL1794573 (1)
2 / 2
P02545 Prelamin-A/C Unclassified protein CHEMBL285123 CHEMBL1614544 (1)
11 / 10
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL11298 CHEMBL1741325 (3)
0 / 1
P54132 Bloom syndrome protein Enzyme CHEMBL285123 CHEMBL1614522 (1) CHEMBL1614067 (1)
1 / 2
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL11298 CHEMBL1741322 (3)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL11298 CHEMBL1741323 (3)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL11298 CHEMBL1741324 (3)
0 / 1
Q7Z2H8 Proton-coupled amino acid transporter 1 Unclassified protein CHEMBL11298 CHEMBL285123 CHEMBL1919336 (4)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL11298 CHEMBL1794536 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL11298 CHEMBL1613914 (2)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL285123 CHEMBL1738442 (2)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#210900 Bloom syndrome; blm P54132
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613688 Long qt syndrome 2; lqt2 Q12809
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#609620 Short qt syndrome 1; sqt1 Q12809

KEGG DISEASE (17)

KEGG disease name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)