KNApSAcK Metabolite C00001433
Metabolite
KNApSAcK Entry
| id | C00001433 |
|---|---|
| Name | Trimethylamine |
| CAS RN | 75-50-3 |
| Standard InChI | InChI=1S/C3H9N/c1-4(2)3/h1-3H3 |
| Standard InChI (Main Layer) | InChI=1S/C3H9N/c1-4(2)3/h1-3H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 8890 |
Link
ChEMBL
| By standard InChI | CHEMBL439723 |
|---|---|
| By standard InChI Main Layer | CHEMBL439723 |
KEGG
| By LinkDB | C00565 |
|---|
CTD
| By CAS RN | C023336 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Lobariaceae | 3 |
List (3)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Lobaria laetevirens | 63752 | Lobariaceae | Fungi | |
| Sticta fuliginosa | 161976 | Lobariaceae | Fungi | |
| Sticta sylvatica | 1161060 | Lobariaceae | Fungi |
Human Protein / Gene in interaction
3 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P17787 | Neuronal acetylcholine receptor subunit beta-2 | CHRN beta | CHEMBL439723 |
CHEMBL751863
(1)
|
1 / 1 |
| P43681 | Neuronal acetylcholine receptor subunit alpha-4 | CHRN alpha | CHEMBL439723 |
CHEMBL751863
(1)
|
1 / 1 |
| P36544 | Neuronal acetylcholine receptor subunit alpha-7 | CHRN alpha | CHEMBL439723 |
CHEMBL751839
(1)
|
0 / 0 |
CTD interaction (5)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C023336 | 2328 |
FMO3
FMOII TMAU dJ127D3.1 |
flavin containing monooxygenase 3 (EC:1.14.13.8 1.14.13.148) | FMO3 gene polymorphism affects the metabolism of trimethylamine |
affects metabolic processing
|
gene |
17050781
17142560 |
| C023336 | 2328 |
FMO3
FMOII TMAU dJ127D3.1 |
flavin containing monooxygenase 3 (EC:1.14.13.8 1.14.13.148) | FMO3 protein results in increased metabolism of trimethylamine |
increases metabolic processing
|
protein |
12214664
17050781 17142560 |
| C023336 | 2328 |
FMO3
FMOII TMAU dJ127D3.1 |
flavin containing monooxygenase 3 (EC:1.14.13.8 1.14.13.148) | FMO3 protein results in increased oxidation of trimethylamine |
increases oxidation
|
protein |
11414682
|
| C023336 | 2328 |
FMO3
FMOII TMAU dJ127D3.1 |
flavin containing monooxygenase 3 (EC:1.14.13.8 1.14.13.148) | FMO3 results in increased oxidation of trimethylamine |
increases oxidation
|
16601883
|
|
| C023336 | 9038 |
TAAR5
PNR RP11-295F4.5 |
trace amine associated receptor 5 | trimethylamine results in increased activity of TAAR5 protein |
increases activity
|
protein |
23393561
|