PCIDB

KNApSAcK Metabolite C00001510

Metabolite

KNApSAcK Entry

id C00001510
Name Theophylline
CAS RN 58-55-9
Standard InChI InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)
Standard InChI (Main Layer) InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)

Cluster

Phytochemical cluster No. 12
KCF-S cluster No. 3446

Link

ChEMBL

By standard InChI CHEMBL190
By standard InChI Main Layer CHEMBL190

KEGG

By LinkDB C07130

CTD

By CAS RN D013806

Human Protein / Gene in interaction

121 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL190 CHEMBL1909136 (2) CHEMBL2071965 (1)
1 / 0
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter CHEMBL190 CHEMBL2169429 (1)
1 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL190 CHEMBL1738312 (1)
0 / 0
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein CHEMBL190 CHEMBL2169431 (1)
0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL190 CHEMBL1909139 (2)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL190 CHEMBL1014033 (1) CHEMBL1909131 (2)
0 / 3
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) CHEMBL190 CHEMBL1909190 (2)
2 / 2
P08246 Neutrophil elastase S1A CHEMBL190 CHEMBL1909195 (2)
2 / 1
P33765 Adenosine receptor A3 Adenosine receptor CHEMBL190 CHEMBL643968 (1) CHEMBL644951 (1)
CHEMBL644388 (1) CHEMBL649054 (1)
CHEMBL830442 (1) CHEMBL860157 (1)
CHEMBL860159 (1) CHEMBL860160 (1)
CHEMBL870209 (1) CHEMBL865349 (1)
CHEMBL894340 (1) CHEMBL947857 (1)
CHEMBL955671 (1) CHEMBL1012734 (1)
CHEMBL1064296 (1) CHEMBL1067001 (1)
CHEMBL1909215 (2)
0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 CHEMBL190 CHEMBL1909201 (2)
0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor CHEMBL190 CHEMBL1909176 (2)
0 / 0
P29466 Caspase-1 C14 CHEMBL190 CHEMBL1909193 (2)
0 / 0
P17252 Protein kinase C alpha type Alpha CHEMBL190 CHEMBL1909198 (2)
0 / 0
P27361 Mitogen-activated protein kinase 3 Erk CHEMBL190 CHEMBL1909199 (2)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL190 CHEMBL1909197 (2)
2 / 2
O15245 Solute carrier family 22 member 1 Drug uniporter CHEMBL190 CHEMBL993349 (1)
0 / 0
Q9Y694 Solute carrier family 22 member 7 Unclassified protein CHEMBL190 CHEMBL2077490 (1) CHEMBL2077618 (1)
0 / 0
Q9Y263 Phospholipase A-2-activating protein Unclassified protein CHEMBL190 CHEMBL1074487 (1)
0 / 0
P29275 Adenosine receptor A2b Adenosine receptor CHEMBL190 CHEMBL641989 (1) CHEMBL641992 (1)
CHEMBL642326 (1) CHEMBL642334 (1)
CHEMBL636450 (1) CHEMBL642110 (1)
CHEMBL643968 (1) CHEMBL848253 (1)
CHEMBL839652 (1) CHEMBL884760 (1)
CHEMBL870844 (1) CHEMBL947856 (1)
CHEMBL1074298 (1) CHEMBL1067000 (1)
CHEMBL1211412 (1)
0 / 0
P00918 Carbonic anhydrase 2 Lyase CHEMBL190 CHEMBL1909123 (2)
1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor CHEMBL190 CHEMBL1909092 (2)
0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase CHEMBL190 CHEMBL1909169 (2)
1 / 1
P25021 Histamine H2 receptor Histamine receptor CHEMBL190 CHEMBL1909157 (2)
0 / 0
P35367 Histamine H1 receptor Histamine receptor CHEMBL190 CHEMBL1909156 (2)
0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine CHEMBL190 CHEMBL1909143 (2)
1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor CHEMBL190 CHEMBL1909174 (2)
0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor CHEMBL190 CHEMBL1909090 (2)
0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor CHEMBL190 CHEMBL1909093 (2)
0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor CHEMBL190 CHEMBL1909127 (2)
0 / 0
P06241 Tyrosine-protein kinase Fyn Src CHEMBL190 CHEMBL1909204 (2)
0 / 0
Q08828 Adenylate cyclase type 1 Enzyme CHEMBL190 CHEMBL645307 (1)
0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr CHEMBL190 CHEMBL1909202 (2)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL190 CHEMBL1909135 (2) CHEMBL2071963 (1)
0 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL190 CHEMBL1909203 (2)
1 / 11
P14416 D(2) dopamine receptor Dopamine receptor CHEMBL190 CHEMBL1909140 (2)
2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL190 CHEMBL1909130 (2)
0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor CHEMBL190 CHEMBL1909120 (2)
0 / 0
P41145 Kappa-type opioid receptor Opioid receptor CHEMBL190 CHEMBL1909181 (2)
0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor CHEMBL190 CHEMBL1909164 (2)
0 / 0
P29274 Adenosine receptor A2a Adenosine receptor CHEMBL190 CHEMBL639494 (1) CHEMBL641989 (1)
CHEMBL641992 (1) CHEMBL642326 (1)
CHEMBL642334 (1) CHEMBL649773 (1)
CHEMBL642110 (1) CHEMBL642121 (1)
CHEMBL642126 (1) CHEMBL643968 (1)
CHEMBL680424 (1) CHEMBL848253 (1)
CHEMBL839651 (1) CHEMBL861067 (1)
CHEMBL860042 (1) CHEMBL870846 (1)
CHEMBL862969 (1) CHEMBL864191 (1)
CHEMBL894344 (1) CHEMBL947855 (1)
CHEMBL955675 (1) CHEMBL1012738 (1)
CHEMBL1074277 (1) CHEMBL1066999 (1)
CHEMBL1803433 (2) CHEMBL1909214 (2)
0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor CHEMBL190 CHEMBL1909175 (2)
0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor CHEMBL190 CHEMBL1909096 (2)
1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr CHEMBL190 CHEMBL1909118 (2)
0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor CHEMBL190 CHEMBL1909166 (2)
1 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 CHEMBL190 CHEMBL1909133 (2)
0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor CHEMBL190 CHEMBL1614456 (1) CHEMBL1613803 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL190 CHEMBL2114780 (1)
0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase CHEMBL190 CHEMBL1909158 (2)
0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor CHEMBL190 CHEMBL1909088 (2)
0 / 0
P21917 D(4) dopamine receptor Dopamine receptor CHEMBL190 CHEMBL1909142 (2)
0 / 0
P30988 Calcitonin receptor Calcitonin receptor CHEMBL190 CHEMBL1909101 (2)
0 / 0
P35462 D(3) dopamine receptor Dopamine receptor CHEMBL190 CHEMBL1909141 (2)
1 / 0
P41143 Delta-type opioid receptor Opioid receptor CHEMBL190 CHEMBL1909180 (2)
0 / 0
Q92731 Estrogen receptor beta NR3A2 CHEMBL190 CHEMBL1909146 (2)
0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor CHEMBL190 CHEMBL1909104 (2)
0 / 0
P25101 Endothelin-1 receptor Endothelin receptor CHEMBL190 CHEMBL1909144 (2)
0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor CHEMBL190 CHEMBL1909100 (2)
0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor CHEMBL190 CHEMBL1909167 (2)
1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor CHEMBL190 CHEMBL1909129 (2)
0 / 0
P08311 Cathepsin G S1A CHEMBL190 CHEMBL1909194 (2)
0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor CHEMBL190 CHEMBL1909110 (2)
1 / 0
P03956 Interstitial collagenase M10A CHEMBL190 CHEMBL1909196 (2)
0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor CHEMBL190 CHEMBL1909119 (2)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL190 CHEMBL2114817 (1)
7 / 3
P09923 Intestinal-type alkaline phosphatase Enzyme CHEMBL190 CHEMBL1074489 (1)
0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme CHEMBL190 CHEMBL1014656 (1) CHEMBL1074488 (1)
3 / 1
P11308 Transcriptional regulator ERG Unclassified protein CHEMBL190 CHEMBL2114924 (1)
1 / 2
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter CHEMBL190 CHEMBL2169430 (1)
1 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL190 CHEMBL1909150 (2)
0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor CHEMBL190 CHEMBL1909171 (2)
2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor CHEMBL190 CHEMBL1909170 (2)
0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor CHEMBL190 CHEMBL1909122 (2)
0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin CHEMBL190 CHEMBL1909109 (2)
2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily CHEMBL190 CHEMBL1909205 (2)
5 / 10
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor CHEMBL190 CHEMBL1909172 (2)
1 / 0
P21452 Substance-K receptor Neurokinin receptor CHEMBL190 CHEMBL1909114 (2)
0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor CHEMBL190 CHEMBL1909125 (2)
0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor CHEMBL190 CHEMBL1909126 (2)
3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor CHEMBL190 CHEMBL1909108 (2)
0 / 0
Q14123 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C PDE_1C CHEMBL190 CHEMBL760662 (1) CHEMBL760937 (1)
CHEMBL760821 (1)
0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor CHEMBL190 CHEMBL1909124 (2)
1 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL190 CHEMBL1909200 (2)
0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme CHEMBL190 CHEMBL1909207 (2)
2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL190 CHEMBL1743265 (1) CHEMBL1909132 (2)
CHEMBL2071962 (1)
0 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 CHEMBL190 CHEMBL2114842 (1)
0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A CHEMBL190 CHEMBL760832 (1) CHEMBL1909186 (2)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL190 CHEMBL1909145 (2)
1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor CHEMBL190 CHEMBL1909091 (2)
1 / 0
P22303 Acetylcholinesterase Hydrolase CHEMBL190 CHEMBL1909212 (2)
1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor CHEMBL190 CHEMBL1909211 (2)
0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor CHEMBL190 CHEMBL1909105 (2)
0 / 0
P35372 Mu-type opioid receptor Opioid receptor CHEMBL190 CHEMBL1909182 (2)
0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor CHEMBL190 CHEMBL1909173 (2)
0 / 0
P25103 Substance-P receptor Neurokinin receptor CHEMBL190 CHEMBL1909113 (2)
0 / 0
P25105 Platelet-activating factor receptor PAF receptor CHEMBL190 CHEMBL1909187 (2)
0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor CHEMBL190 CHEMBL1909168 (2)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL190 CHEMBL1909134 (2) CHEMBL2071964 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL190 CHEMBL1909138 (2) CHEMBL2071966 (1)
CHEMBL2071967 (1)
0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 CHEMBL190 CHEMBL1909137 (2)
0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine CHEMBL190 CHEMBL1909094 (2)
1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor CHEMBL190 CHEMBL1909087 (2)
0 / 0
P30542 Adenosine receptor A1 Adenosine receptor CHEMBL190 CHEMBL633044 (1) CHEMBL643495 (1)
CHEMBL643968 (1) CHEMBL848253 (1)
CHEMBL830050 (1) CHEMBL829691 (1)
CHEMBL831245 (1) CHEMBL860040 (1)
CHEMBL860159 (1) CHEMBL860160 (1)
CHEMBL870845 (1) CHEMBL862970 (1)
CHEMBL894342 (1) CHEMBL947854 (1)
CHEMBL972850 (1) CHEMBL955673 (1)
CHEMBL1012736 (1) CHEMBL1074297 (1)
CHEMBL1066998 (1) CHEMBL1909213 (2)
0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor CHEMBL190 CHEMBL1909089 (2)
0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 CHEMBL190 CHEMBL1909116 (2)
1 / 1
P06239 Tyrosine-protein kinase Lck Src CHEMBL190 CHEMBL1909206 (2)
0 / 1
O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE_2A CHEMBL190 CHEMBL759914 (1)
0 / 0
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor CHEMBL190 CHEMBL1909128 (2)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL190 CHEMBL1738442 (2)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL190 CHEMBL2354311 (1)
1 / 0
Q08493 cAMP-specific 3',5'-cyclic phosphodiesterase 4C PDE_4C CHEMBL190 CHEMBL685651 (1) CHEMBL764551 (1)
CHEMBL764552 (1) CHEMBL766268 (1)
CHEMBL761484 (1) CHEMBL763662 (1)
CHEMBL821509 (1) CHEMBL824111 (1)
0 / 0
Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE_4B CHEMBL190 CHEMBL685651 (1) CHEMBL764551 (1)
CHEMBL764552 (1) CHEMBL766268 (1)
CHEMBL761484 (1) CHEMBL763662 (1)
CHEMBL821509 (1) CHEMBL824111 (1)
0 / 0
P27815 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE_4A CHEMBL190 CHEMBL685651 (1) CHEMBL764551 (1)
CHEMBL764552 (1) CHEMBL766268 (1)
CHEMBL761484 (1) CHEMBL763662 (1)
CHEMBL821509 (1) CHEMBL824111 (1)
0 / 0
Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE_4D CHEMBL190 CHEMBL685651 (1) CHEMBL764551 (1)
CHEMBL764552 (1) CHEMBL766268 (1)
CHEMBL761484 (1) CHEMBL763662 (1)
CHEMBL821509 (1) CHEMBL824111 (1)
1 / 0
Q13370 cGMP-inhibited 3',5'-cyclic phosphodiesterase B PDE_3B CHEMBL190 CHEMBL871970 (1) CHEMBL764829 (1)
CHEMBL761134 (1)
0 / 0
Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE_3A CHEMBL190 CHEMBL871970 (1) CHEMBL764829 (1)
CHEMBL761134 (1)
0 / 0
P54750 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE_1A CHEMBL190 CHEMBL760662 (1) CHEMBL760937 (1)
0 / 0
Q01064 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE_1B CHEMBL190 CHEMBL760662 (1) CHEMBL760937 (1)
0 / 0
Q9NY46 Sodium channel protein type 3 subunit alpha SCN alpha, NaV1.x CHEMBL190 CHEMBL806153 (1) CHEMBL806154 (1)
0 / 0
Q99250 Sodium channel protein type 2 subunit alpha SCN alpha, NaV1.x CHEMBL190 CHEMBL806153 (1) CHEMBL806154 (1)
2 / 2
P35498 Sodium channel protein type 1 subunit alpha SCN alpha, NaV1.x CHEMBL190 CHEMBL806153 (1) CHEMBL806154 (1)
3 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL190 CHEMBL2354287 (1)
1 / 1

CTD interaction (551)

compound gene gene name gene description interaction interaction type form reference
pmid
D013806 83451 ABHD11
WBSCR21
abhydrolase domain containing 11 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ABHD11 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 27 ABL2
ABLL
ARG
c-abl oncogene 2, non-receptor tyrosine kinase (EC:2.7.10.2) Theophylline results in decreased expression of ABL2 mRNA decreases expression
mRNA 16083514
D013806 30 ACAA1
ACAA
PTHIO
THIO
acetyl-CoA acyltransferase 1 (EC:2.3.1.16) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ACAA1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 11332 ACOT7
ACH1
ACT
BACH
CTE-II
LACH
LACH1
RP1-120G22.10
hBACH
acyl-CoA thioesterase 7 (EC:3.1.2.2) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ACOT7 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 59 ACTA2
AAT6
ACTSA
MYMY5
actin, alpha 2, smooth muscle, aorta Theophylline inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] decreases reaction
/ increases expression
protein 16430859
D013806 10097 ACTR2
ARP2
ARP2 actin-related protein 2 homolog (yeast) Theophylline results in decreased expression of ACTR2 mRNA decreases expression
mRNA 16083514
D013806 10096 ACTR3
ARP3
ARP3 actin-related protein 3 homolog (yeast) Theophylline results in decreased expression of ACTR3 mRNA decreases expression
mRNA 16083514
D013806 132612 ADAD1
Tenr
adenosine deaminase domain containing 1 (testis-specific) Theophylline results in decreased expression of ADAD1 mRNA decreases expression
mRNA 18951874
D013806 57188 ADAMTSL3
ADAMTS-like 3 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ADAMTSL3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 157 ADRBK2
BARK2
GRK3
adrenergic, beta, receptor kinase 2 (EC:2.7.11.15) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ADRBK2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 157 ADRBK2
BARK2
GRK3
adrenergic, beta, receptor kinase 2 (EC:2.7.11.15) Theophylline results in decreased expression of ADRBK2 mRNA decreases expression
mRNA 18951874
D013806 27125 AFF4
AF5Q31
MCEF
AF4/FMR2 family, member 4 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of AFF4 protein affects cotreatment
/ increases expression
protein 18951874
D013806 3267 AGFG1
HRB
RAB
RIP
ArfGAP with FG repeats 1 Theophylline results in increased expression of AGFG1 mRNA increases expression
mRNA 18951874
D013806 25909 AHCTF1
ELYS
MST108
TMBS62
AT hook containing transcription factor 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of AHCTF1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 84335 AKT1S1
Lobe
PRAS40
AKT1 substrate 1 (proline-rich) Theophylline results in increased expression of AKT1S1 mRNA increases expression
mRNA 18951874
D013806 230 ALDOC
ALDC
aldolase C, fructose-bisphosphate (EC:4.1.2.13) Theophylline results in decreased expression of ALDOC mRNA decreases expression
mRNA 16083514
D013806 79796 ALG9
CDG1L
DIBD1
LOH11CR1J
ALG9, alpha-1,2-mannosyltransferase (EC:2.4.1.259 2.4.1.261) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ALG9 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 348094 ANKDD1A
ankyrin repeat and death domain containing 1A Theophylline results in increased expression of ANKDD1A mRNA increases expression
mRNA 18951874
D013806 81573 ANKRD13C
RP4-677H15.5
dJ677H15.3
ankyrin repeat domain 13C [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ANKRD13C protein affects cotreatment
/ increases expression
protein 18951874
D013806 91526 ANKRD44
PP6-ARS-B
ankyrin repeat domain 44 Theophylline results in increased expression of ANKRD44 mRNA increases expression
mRNA 18951874
D013806 26 AOC1
ABP
ABP1
DAO
DAO1
KAO
amine oxidase, copper containing 1 (EC:1.4.3.22) Theophylline results in decreased expression of AOC1 mRNA decreases expression
mRNA 18951874
D013806 375 ARF1
ADP-ribosylation factor 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ARF1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 55843 ARHGAP15
BM046
Rho GTPase activating protein 15 Theophylline results in increased expression of ARHGAP15 mRNA increases expression
mRNA 18951874
D013806 196528 ARID2
BAF200
p200
AT rich interactive domain 2 (ARID, RFX-like) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ARID2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 25852 ARMC8
GID5
HSPC056
VID28
armadillo repeat containing 8 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ARMC8 protein affects cotreatment
/ increases expression
protein 18951874
D013806 405 ARNT
HIF-1-beta
HIF-1beta
HIF1-beta
HIF1B
HIF1BETA
TANGO
bHLHe2
aryl hydrocarbon receptor nuclear translocator [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ARNT protein affects cotreatment
/ increases expression
protein 18951874
D013806 411 ARSB
ASB
G4S
MPS6
arylsulfatase B (EC:3.1.6.12) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ARSB protein affects cotreatment
/ decreases expression
protein 18951874
D013806 64422 ATG3
APG3
APG3-LIKE
APG3L
PC3-96
autophagy related 3 Theophylline results in increased expression of ATG3 mRNA increases expression
mRNA 18951874
D013806 27109 ATP5S
ATPW
FB
HSU79253
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) (EC:3.6.1.14) Theophylline results in decreased expression of ATP5S mRNA decreases expression
mRNA 18951874
D013806 91647 ATPAF2
ATP12
ATP12p
MC5DN1
ATP synthase mitochondrial F1 complex assembly factor 2 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ATPAF2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 546 ATRX
ATR2
JMS
MRXHF1
RAD54
RAD54L
SFM1
SHS
XH2
XNP
ZNF-HX
alpha thalassemia/mental retardation syndrome X-linked (EC:3.6.4.12) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ATRX protein affects cotreatment
/ increases expression
protein 18951874
D013806 9212 AURKB
AIK2
AIM-1
AIM1
ARK2
AurB
IPL1
PPP1R48
STK12
STK5
aurkb-sv1
aurkb-sv2
aurora kinase B (EC:2.7.11.1) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of AURKB protein affects cotreatment
/ decreases expression
protein 18951874
D013806 64343 AZI2
AZ2
NAP1
TILP
5-azacytidine induced 2 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of AZI2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 64343 AZI2
AZ2
NAP1
TILP
5-azacytidine induced 2 Theophylline results in decreased expression of AZI2 mRNA decreases expression
mRNA 18951874
D013806 148789 B3GALNT2
B3GalNAc-T2
MDDGA11
beta-1,3-N-acetylgalactosaminyltransferase 2 (EC:2.4.1.-) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of B3GALNT2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 11285 B4GALT7
EDSP1
XGALT1
XGPT1
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (EC:2.4.1.133) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of B4GALT7 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 9529 BAG5
BAG-5
BCL2-associated athanogene 5 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of BAG5 protein affects cotreatment
/ increases expression
protein 18951874
D013806 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 IL4 protein inhibits the reaction [Theophylline results in decreased expression of BCL2 protein] decreases expression
/ decreases reaction
protein 8822937
D013806 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [Theophylline co-treated with Cisplatin] results in decreased expression of BCL2 protein affects cotreatment
/ decreases expression
protein 10891529
15645133
D013806 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [Theophylline co-treated with gemcitabine] results in decreased expression of BCL2 protein affects cotreatment
/ decreases expression
protein 15645133
D013806 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Theophylline results in decreased expression of BCL2 mRNA decreases expression
mRNA 8822937
D013806 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Theophylline results in decreased expression of BCL2 protein decreases expression
protein 8822937
9312165
10877050
10891529
15313391
D013806 9274 BCL7C
B-cell CLL/lymphoma 7C [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of BCL7C protein affects cotreatment
/ decreases expression
protein 18951874
D013806 613 BCR
ALL
BCR1
CML
D22S11
D22S662
PHL
breakpoint cluster region (EC:2.7.11.1) Theophylline results in increased expression of BCR mRNA increases expression
mRNA 16083514
D013806 29760 BLNK
AGM4
BASH
BLNK-S
LY57
SLP-65
SLP65
bca
B-cell linker Theophylline results in increased expression of BLNK mRNA increases expression
mRNA 16083514
D013806 2186 BPTF
FAC1
FALZ
NURF301
bromodomain PHD finger transcription factor Theophylline results in decreased expression of BPTF mRNA decreases expression
mRNA 18951874
D013806 9577 BRE
BRCC4
BRCC45
brain and reproductive organ-expressed (TNFRSF1A modulator) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of BRE protein affects cotreatment
/ decreases expression
protein 18951874
D013806 84280 BTBD10
GMRP-1
GMRP1
BTB (POZ) domain containing 10 Theophylline results in increased expression of BTBD10 mRNA increases expression
mRNA 16083514
D013806 10950 BTG3
ANA
TOB5
TOB55
TOFA
BTG family, member 3 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of BTG3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 55216 C11orf57
chromosome 11 open reading frame 57 Theophylline results in increased expression of C11ORF57 mRNA increases expression
mRNA 18951874
D013806 730094 C16orf52
chromosome 16 open reading frame 52 Theophylline results in increased expression of C16ORF52 mRNA increases expression
mRNA 18951874
D013806 57020 C16orf62
chromosome 16 open reading frame 62 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of C16ORF62 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 148137 C19orf55
chromosome 19 open reading frame 55 Theophylline results in increased expression of C19ORF55 mRNA increases expression
mRNA 18951874
D013806 25912 C1orf43
NICE-3
NS5ATP4
S863-3
chromosome 1 open reading frame 43 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of C1ORF43 protein affects cotreatment
/ increases expression
protein 18951874
D013806 9847 C2CD5
CDP138
KIAA0528
C2 calcium-dependent domain containing 5 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of C2CD5 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 84077 C3orf20
chromosome 3 open reading frame 20 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of C3ORF20 protein affects cotreatment
/ increases expression
protein 18951874
D013806 727 C5
C5a
C5b
CPAMD4
complement component 5 Theophylline inhibits the reaction [C5 protein modified form results in increased abundance of Superoxides] decreases reaction
/ increases abundance
protein 10947063
D013806 727 C5
C5a
C5b
CPAMD4
complement component 5 Theophylline promotes the reaction [C5 protein modified form results in increased abundance of Superoxides] increases abundance
/ increases reaction
protein 10947063
D013806 817 CAMK2D
CAMKD
calcium/calmodulin-dependent protein kinase II delta (EC:2.7.11.17) Theophylline results in decreased expression of CAMK2D mRNA decreases expression
mRNA 18951874
D013806 55832 CAND1
TIP120
TIP120A
cullin-associated and neddylation-dissociated 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CAND1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 4076 CAPRIN1
GPIAP1
GPIP137
M11S1
RNG105
p137GPI
cell cycle associated protein 1 Theophylline results in increased expression of CAPRIN1 mRNA increases expression
mRNA 18951874
D013806 829 CAPZA1
CAPPA1
CAPZ
CAZ1
capping protein (actin filament) muscle Z-line, alpha 1 Theophylline results in decreased expression of CAPZA1 mRNA decreases expression
mRNA 16083514
D013806 835 CASP2
CASP-2
ICH1
NEDD-2
NEDD2
PPP1R57
caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CASP2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Theophylline results in increased activity of CASP3 protein increases activity
protein 14634331
D013806 857 CAV1
BSCL3
CGL3
MSTP085
PPH3
VIP21
CAV
caveolin 1, caveolae protein, 22kDa Theophylline results in increased expression of CAV1 mRNA increases expression
mRNA 16083514
D013806 81576 CCDC130
coiled-coil domain containing 130 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCDC130 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 57821 CCDC181
C1orf114
RP1-206D15.2
coiled-coil domain containing 181 Theophylline results in decreased expression of CCDC181 mRNA decreases expression
mRNA 18951874
D013806 728621 CCDC30
PFD6L
PFDN6L
coiled-coil domain containing 30 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCDC30 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 79780 CCDC82
HSPC048
coiled-coil domain containing 82 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCDC82 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 54520 CCDC93
coiled-coil domain containing 93 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCDC93 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 6347 CCL2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
SCYA2
SMC-CF
chemokine (C-C motif) ligand 2 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCL2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 [Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CCND1 protein increases abundance
/ increases expression
protein 21693435
D013806 945 CD33
SIGLEC-3
SIGLEC3
p67
CD33 molecule [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CD33 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 948 CD36
BDPLT10
CHDS7
FAT
GP3B
GP4
GPIV
PASIV
SCARB3
CD36 molecule (thrombospondin receptor) Theophylline results in decreased expression of CD36 mRNA decreases expression
mRNA 16083514
D013806 920 CD4
CD4mut
CD4 molecule Theophylline results in decreased expression of CD4 protein decreases expression
protein 11408767
D013806 8621 CDK13
CDC2L
CDC2L5
CHED
hCDK13
cyclin-dependent kinase 13 (EC:2.7.11.23 2.7.11.22) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CDK13 protein affects cotreatment
/ increases expression
protein 18951874
D013806 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) [Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CDKN1B protein increases abundance
/ increases expression
protein 21693435
D013806 1028 CDKN1C
BWCR
BWS
KIP2
WBS
p57
p57Kip2
cyclin-dependent kinase inhibitor 1C (p57, Kip2) Theophylline results in increased expression of CDKN1C mRNA increases expression
mRNA 16083514
D013806 80184 CEP290
3H11Ag
BBS14
CT87
JBTS5
LCA10
MKS4
NPHP6
POC3
SLSN6
rd16
centrosomal protein 290kDa Theophylline results in decreased expression of CEP290 mRNA decreases expression
mRNA 18951874
D013806 80254 CEP63
centrosomal protein 63kDa [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CEP63 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 10390 CEPT1
choline/ethanolamine phosphotransferase 1 (EC:2.7.8.2 2.7.8.1) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CEPT1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 1081 CGA
CG-ALPHA
FSHA
GPHA1
GPHa
HCG
LHA
TSHA
glycoprotein hormones, alpha polypeptide [Theophylline co-treated with Butyric Acid] results in increased expression of CGA mRNA affects cotreatment
/ increases expression
mRNA 1693836
D013806 1081 CGA
CG-ALPHA
FSHA
GPHA1
GPHa
HCG
LHA
TSHA
glycoprotein hormones, alpha polypeptide Theophylline inhibits the reaction [Butyric Acid results in decreased stability of CGA mRNA] decreases reaction
/ decreases stability
mRNA 1693837
D013806 1081 CGA
CG-ALPHA
FSHA
GPHA1
GPHa
HCG
LHA
TSHA
glycoprotein hormones, alpha polypeptide Theophylline promotes the reaction [Butyric Acid results in increased expression of CGA protein] increases expression
/ increases reaction
protein 1693836
1693837
D013806 1081 CGA
CG-ALPHA
FSHA
GPHA1
GPHa
HCG
LHA
TSHA
glycoprotein hormones, alpha polypeptide Theophylline results in increased expression of CGA protein increases expression
protein 1693837
D013806 1081 CGA
CG-ALPHA
FSHA
GPHA1
GPHa
HCG
LHA
TSHA
glycoprotein hormones, alpha polypeptide Theophylline results in increased stability of CGA mRNA increases stability
mRNA 1693837
D013806 23274 CLEC16A
Gop-1
KIAA0350
C-type lectin domain family 16, member A Theophylline results in decreased expression of CLEC16A mRNA decreases expression
mRNA 18951874
D013806 165530 CLEC4F
CLECSF13
KCLR
C-type lectin domain family 4, member F Theophylline results in decreased expression of CLEC4F mRNA decreases expression
mRNA 18951874
D013806 81570 CLPB
HSP78
SKD3
ClpB caseinolytic peptidase B homolog (E. coli) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CLPB protein affects cotreatment
/ decreases expression
protein 18951874
D013806 81570 CLPB
HSP78
SKD3
ClpB caseinolytic peptidase B homolog (E. coli) Theophylline results in increased expression of CLPB mRNA increases expression
mRNA 18951874
D013806 1277 COL1A1
OI4
collagen, type I, alpha 1 Theophylline inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] decreases reaction
/ increases expression
mRNA 16430859
D013806 1277 COL1A1
OI4
collagen, type I, alpha 1 Theophylline promotes the reaction [Dexamethasone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]] decreases reaction
/ increases expression
/ increases reaction
mRNA 16430859
D013806 51117 COQ4
CGI-92
coenzyme Q4 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of COQ4 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 1329 COX5B
COXVB
cytochrome c oxidase subunit Vb (EC:1.9.3.1) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of COX5B protein affects cotreatment
/ decreases expression
protein 18951874
D013806 1368 CPM
carboxypeptidase M (EC:3.4.17.12) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CPM protein affects cotreatment
/ decreases expression
protein 18951874
D013806 8904 CPNE1
COPN1
CPN1
copine I Theophylline binds to CPNE1 protein affects binding
protein 18951874
D013806 78987 CRELD1
AVSD2
CIRRIN
cysteine-rich with EGF-like domains 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CRELD1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 64784 CRTC3
TORC-3
TORC3
CREB regulated transcription coactivator 3 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CRTC3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 1437 CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage) [Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 12070353
D013806 1437 CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage) Theophylline inhibits the reaction [CSF2 protein results in increased expression of EDN1 mRNA] decreases reaction
/ increases expression
protein 10374451
D013806 1437 CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage) Theophylline promotes the reaction [IL1B protein results in increased secretion of CSF2 protein] increases reaction
/ increases secretion
protein 12070353
D013806 1437 CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage) Theophylline results in decreased expression of CSF2 mRNA decreases expression
mRNA 10596698
D013806 1437 CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage) trichostatin A inhibits the reaction [[Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]] affects cotreatment
/ decreases reaction
/ increases secretion
protein 12070353
D013806 1440 CSF3
C17orf33
CSF3OS
GCSF
G-CSF
colony stimulating factor 3 (granulocyte) Theophylline results in increased expression of CSF3 protein increases expression
protein 7540958
D013806 1454 CSNK1E
CKIepsilon
HCKIE
casein kinase 1, epsilon (EC:2.7.11.1) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CSNK1E protein affects cotreatment
/ decreases expression
protein 18951874
D013806 1503 CTPS1
CTPS
CTP synthase 1 (EC:6.3.4.2) Theophylline results in decreased expression of CTPS1 mRNA decreases expression
mRNA 16083514
D013806 1506 CTRL
CTRL1
chymotrypsin-like (EC:3.4.21.-) Theophylline results in increased expression of CTRL mRNA increases expression
mRNA 18951874
D013806 1508 CTSB
APPS
CPSB
cathepsin B (EC:3.4.22.1) Theophylline results in increased expression of CTSB mRNA increases expression
mRNA 16083514
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) CYP1A2 gene SNP affects the metabolism of Theophylline affects metabolic processing
gene 20797314
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) CYP1A2 gene SNP affects the susceptibility to Theophylline affects response to substance
gene 12732846
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) CYP1A2 promoter SNP affects the hydroxylation of Theophylline affects hydroxylation
promoter 16841220
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) CYP1A2 protein affects the metabolism of Theophylline affects metabolic processing
protein 9029748
12732846
15692829
15948934
15970798
16841220
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) CYP1A2 protein results in increased chemical synthesis of Theophylline increases chemical synthesis
protein 1302044
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) CYP1A2 protein results in increased metabolism of Theophylline increases metabolic processing
protein 9701106
11483122
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) Fluvoxamine inhibits the reaction [CYP1A2 protein affects the metabolism of Theophylline] affects metabolic processing
/ decreases reaction
protein 9029748
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) Griseofulvin promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline] affects metabolic processing
/ increases reaction
protein 9029748
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) [Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline] affects cotreatment
/ decreases reaction
/ increases metabolic processing
protein 11408986
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) Theophylline results in decreased activity of CYP1A2 protein decreases activity
protein 11465391
D013806 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) zafirlukast inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline] decreases reaction
/ increases metabolic processing
protein 9701106
D013806 1571 CYP2E1
CPE1
CYP2E
P450-J
P450C2E
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) CYP2E1 promoter SNP affects the hydroxylation of Theophylline affects hydroxylation
promoter 16841220
D013806 1571 CYP2E1
CPE1
CYP2E
P450-J
P450C2E
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) CYP2E1 protein affects the metabolism of Theophylline affects metabolic processing
protein 15948934
16841220
D013806 1571 CYP2E1
CPE1
CYP2E
P450-J
P450C2E
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) CYP2E1 protein results in increased chemical synthesis of Theophylline increases chemical synthesis
protein 1302044
D013806 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) [Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP3A4 protein results in increased metabolism of Theophylline] affects cotreatment
/ decreases reaction
/ increases metabolic processing
protein 11408986
D013806 10800 CYSLTR1
CYSLT1
CYSLT1R
CYSLTR
HMTMF81
cysteinyl leukotriene receptor 1 Theophylline results in decreased expression of CYSLTR1 mRNA decreases expression
mRNA 18951874
D013806 1601 DAB2
DOC-2
DOC2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DAB2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 147906 DACT3
DAPPER3
RRR1
dishevelled-binding antagonist of beta-catenin 3 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DACT3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 285761 DCBLD1
dJ94G16.1
discoidin, CUB and LCCL domain containing 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of DCBLD1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 326709 Theophylline results in increased expression of DDEF1 mRNA increases expression
mRNA 18951874
D013806 84301 DDI2
RP4-680D5.5
DNA-damage inducible 1 homolog 2 (S. cerevisiae) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of DDI2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 308585 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DHRS10 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 1659 DHX8
DDX8
HRH1
PRP22
PRPF22
DEAH (Asp-Glu-Ala-His) box polypeptide 8 (EC:3.6.4.13) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DHX8 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 1739 DLG1
DLGH1
SAP-97
SAP97
dJ1061C18.1.1
hdlg
discs, large homolog 1 (Drosophila) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of DLG1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 29103 DNAJC15
DNAJD1
HSD18
MCJ
DnaJ (Hsp40) homolog, subfamily C, member 15 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of DNAJC15 protein affects cotreatment
/ increases expression
protein 18951874
D013806 3338 DNAJC4
DANJC4
HSPF2
MCG18
DnaJ (Hsp40) homolog, subfamily C, member 4 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DNAJC4 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 9732 DOCK4
dedicator of cytokinesis 4 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of DOCK4 protein affects cotreatment
/ increases expression
protein 18951874
D013806 22845 DOLK
CDG1M
DK
DK1
SEC59
TMEM15
dolichol kinase (EC:2.7.1.108) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DOLK protein affects cotreatment
/ decreases expression
protein 18951874
D013806 116749 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DRB1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 1816 DRD5
DBDR
DRD1B
DRD1L2
dopamine receptor D5 Theophylline results in increased expression of DRD5 mRNA increases expression
mRNA 18951874
D013806 142679 DUSP19
DUSP17
LMWDSP3
SKRP1
TS-DSP1
dual specificity phosphatase 19 (EC:3.1.3.16 3.1.3.48) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DUSP19 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 124454 EARS2
COXPD12
MSE1
glutamyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.17) Theophylline results in increased expression of EARS2 mRNA increases expression
mRNA 18951874
D013806 1906 EDN1
ET1
HDLCQ7
PPET1
endothelin 1 Theophylline inhibits the reaction [CSF2 protein results in increased expression of EDN1 mRNA] decreases reaction
/ increases expression
mRNA 10374451
D013806 112399 EGLN3
HIFP4H3
HIFPH3
PHD3
egl-9 family hypoxia-inducible factor 3 (EC:1.14.11.29) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of EGLN3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 1968 EIF2S3
EIF2
EIF2G
EIF2gamma
eIF-2gA
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa Theophylline results in increased expression of EIF2S3 mRNA increases expression
mRNA 16083514
D013806 8661 EIF3A
EIF3
EIF3S10
P167
TIF32
eIF3-p170
eIF3-theta
p180
p185
eukaryotic translation initiation factor 3, subunit A Theophylline results in increased expression of EIF3A mRNA increases expression
mRNA 16083514
D013806 8662 EIF3B
EIF3-ETA
EIF3-P110
EIF3-P116
EIF3S9
PRT1
eukaryotic translation initiation factor 3, subunit B Theophylline results in increased expression of EIF3B mRNA increases expression
mRNA 18951874
D013806 3646 EIF3E
EIF3-P48
EIF3S6
INT6
eIF3-p46
eukaryotic translation initiation factor 3, subunit E Theophylline results in decreased expression of EIF3E mRNA decreases expression
mRNA 16083514
D013806 1975 EIF4B
EIF-4B
PRO1843
eukaryotic translation initiation factor 4B Theophylline results in increased expression of EIF4B mRNA increases expression
mRNA 16083514
D013806 1983 EIF5
EIF-5
EIF-5A
eukaryotic translation initiation factor 5 Theophylline results in decreased expression of EIF5 mRNA decreases expression
mRNA 16083514
D013806 54859 ELP6
C3orf75
TMEM103
elongator acetyltransferase complex subunit 6 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ELP6 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 55831 EMC3
POB
TMEM111
ER membrane protein complex subunit 3 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of EMC3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 957 ENTPD5
CD39L4
NTPDase-5
PCPH
ectonucleoside triphosphate diphosphohydrolase 5 (EC:3.6.1.6 3.6.1.42) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ENTPD5 protein affects cotreatment
/ increases expression
protein 18951874
D013806 57724 EPG5
HEEW1
KIAA1632
VICIS
hEPG5
ectopic P-granules autophagy protein 5 homolog (C. elegans) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of EPG5 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 2060 EPS15
AF-1P
AF1P
MLLT5
epidermal growth factor receptor pathway substrate 15 Theophylline results in decreased expression of EPS15 mRNA decreases expression
mRNA 18951874
D013806 54869 EPS8L1
DRC3
EPS8R1
EPS8-like 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of EPS8L1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 2073 ERCC5
COFS3
ERCM2
UVDR
XPG
XPGC
excision repair cross-complementing rodent repair deficiency, complementation group 5 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ERCC5 protein affects cotreatment
/ increases expression
protein 18951874
D013806 2077 ERF
CRS4
PE-2
PE2
Ets2 repressor factor [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ERF protein affects cotreatment
/ increases expression
protein 18951874
D013806 57222 ERGIC1
ERGIC-32
ERGIC32
NET24
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ERGIC1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 10613 ERLIN1
C10orf69
Erlin-1
KE04
KEO4
SPFH1
ER lipid raft associated 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ERLIN1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 11160 ERLIN2
C8orf2
Erlin-2
NET32
SPFH2
SPG18
ER lipid raft associated 2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ERLIN2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 733318 Theophylline results in increased expression of EVI1 mRNA increases expression
mRNA 16083514
D013806 2124 EVI2B
CD361
D17S376
EVDB
ecotropic viral integration site 2B Theophylline results in decreased expression of EVI2B mRNA decreases expression
mRNA 16083514
D013806 51010 EXOSC3
PCH1B
RP11-3J10.8
RRP40
Rrp40p
bA3J10.7
hRrp-40
p10
exosome component 3 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of EXOSC3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 54512 EXOSC4
RRP41
RRP41A
Rrp41p
SKI6
Ski6p
hRrp41p
p12A
exosome component 4 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of EXOSC4 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 2140 EYA3
eyes absent homolog 3 (Drosophila) (EC:3.1.3.48) Theophylline results in increased expression of EYA3 mRNA increases expression
mRNA 18951874
D013806 3995 FADS3
CYB5RP
LLCDL3
fatty acid desaturase 3 (EC:1.14.19.-) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FADS3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 55731 FAM222B
C17orf63
family with sequence similarity 222, member B [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FAM222B protein affects cotreatment
/ increases expression
protein 18951874
D013806 26269 FBXO8
FBS
FBX8
F-box protein 8 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FBXO8 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 9873 FCHSD2
NWK
SH3MD3
FCH and double SH3 domains 2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FCHSD2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 2232 FDXR
ADXR
ferredoxin reductase (EC:1.18.1.6) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FDXR protein affects cotreatment
/ decreases expression
protein 18951874
D013806 2275 FHL3
SLIM2
four and a half LIM domains 3 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FHL3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 9158 FIBP
FGFIBP
FIBP-1
fibroblast growth factor (acidic) intracellular binding protein [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FIBP protein affects cotreatment
/ decreases expression
protein 18951874
D013806 81608 FIP1L1
FIP1
Rhe
hFip1
factor interacting with PAPOLA and CPSF1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FIP1L1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 128486 FITM2
C20orf142
Fit2
dJ881L22.2
fat storage-inducing transmembrane protein 2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FITM2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 2319 FLOT2
ECS-1
ECS1
ESA
ESA1
M17S1
flotillin 2 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FLOT2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 23360 FNBP4
FBP30
formin binding protein 4 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FNBP4 protein affects cotreatment
/ increases expression
protein 18951874
D013806 2342 FNTB
FPTB
farnesyltransferase, CAAX box, beta (EC:2.5.1.58) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FNTB protein affects cotreatment
/ increases expression
protein 18951874
D013806 2348 FOLR1
FBP
FOLR
folate receptor 1 (adult) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FOLR1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 2295 FOXF2
FKHL6
FREAC-2
FREAC2
forkhead box F2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FOXF2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 3607 FOXK2
ILF
ILF-1
ILF1
forkhead box K2 Theophylline results in increased expression of FOXK2 mRNA increases expression
mRNA 16083514
D013806 83856 FSD1L
CCDC10
CSDUFD1
FSD1CL
FSD1NL
MIR1
fibronectin type III and SPRY domain containing 1-like Theophylline results in increased expression of FSD1L mRNA increases expression
mRNA 18951874
D013806 23710 GABARAPL1
APG8-LIKE
APG8L
ATG8
ATG8B
ATG8L
GEC1
GABA(A) receptor-associated protein like 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GABARAPL1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 2570 GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GABRR2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of GDF15 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 2673 GFPT1
CMSTA1
GFA
GFAT
GFAT_1
GFAT1
GFAT1m
GFPT
GFPT1L
MSLG
glutamine--fructose-6-phosphate transaminase 1 (EC:2.6.1.16) Theophylline results in increased expression of GFPT1 mRNA increases expression
mRNA 16083514
D013806 9453 GGPS1
GGPPS
GGPPS1
geranylgeranyl diphosphate synthase 1 (EC:2.5.1.1 2.5.1.10 2.5.1.29) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of GGPS1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 80318 GKAP1
GKAP42
G kinase anchoring protein 1 Theophylline results in increased expression of GKAP1 mRNA increases expression
mRNA 18951874
D013806 10539 GLRX3
GLRX4
GRX3
GRX4
PICOT
TXNL2
TXNL3
glutaredoxin 3 Theophylline results in increased expression of GLRX3 mRNA increases expression
mRNA 18951874
D013806 2744 GLS
AAD20
GAC
GAM
GLS1
KGA
glutaminase (EC:3.5.1.2) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GLS protein affects cotreatment
/ increases expression
protein 18951874
D013806 2782 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GNB1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 2782 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1 Theophylline results in decreased expression of GNB1 mRNA decreases expression
mRNA 16083514
D013806 23131 GPATCH8
GPATC8
KIAA0553
G patch domain containing 8 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GPATCH8 protein affects cotreatment
/ increases expression
protein 18951874
D013806 2823 GPM6A
GPM6
M6A
glycoprotein M6A Theophylline results in increased expression of GPM6A mRNA increases expression
mRNA 16083514
D013806 283554 GPR137C
TM7SF1L2
G protein-coupled receptor 137C Theophylline results in increased expression of GPR137C mRNA increases expression
mRNA 18951874
D013806 2916 GRM6
CSNB1B
GPRC1F
MGLUR6
mGlu6
glutamate receptor, metabotropic 6 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GRM6 protein affects cotreatment
/ increases expression
protein 18951874
D013806 2946 GSTM2
GST4
GSTM
GSTM2-2
GTHMUS
glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18) Theophylline results in decreased expression of GSTM2 mRNA decreases expression
mRNA 16083514
D013806 3033 HADH
HAD
HADH1
HADHSC
HCDH
HHF4
MSCHAD
SCHAD
hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35) Theophylline results in decreased expression of HADH mRNA decreases expression
mRNA 16083514
D013806 24442 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HD protein affects cotreatment
/ decreases expression
protein 18951874
D013806 3065 HDAC1
GON-10
HD1
RPD3
RPD3L1
histone deacetylase 1 (EC:3.5.1.98) Theophylline results in increased activity of HDAC1 protein increases activity
protein 12070353
D013806 3065 HDAC1
GON-10
HD1
RPD3
RPD3L1
histone deacetylase 1 (EC:3.5.1.98) Theophylline results in increased expression of HDAC1 protein increases expression
protein 12070353
15337792
D013806 3066 HDAC2
HD2
RPD3
YAF1
histone deacetylase 2 (EC:3.5.1.98) Theophylline results in increased expression of HDAC2 protein increases expression
protein 15337792
D013806 8841 HDAC3
HD3
RPD3
RPD3-2
histone deacetylase 3 (EC:3.5.1.98) Theophylline results in increased activity of HDAC3 protein increases activity
protein 12070353
D013806 113510 HELQ
HEL308
helicase, POLQ-like (EC:3.6.4.12) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HELQ protein affects cotreatment
/ decreases expression
protein 18951874
D013806 51409 HEMK1
HEMK
MTQ1
HemK methyltransferase family member 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HEMK1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 11147 HHLA3
HERV-H LTR-associating 3 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HHLA3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 3094 HINT1
HINT
NMAN
PKCI-1
PRKCNH1
histidine triad nucleotide binding protein 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of HINT1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 8330 HIST1H2AK
H2A/d
H2AFD
histone cluster 1, H2ak Theophylline results in decreased expression of HIST1H2AK mRNA decreases expression
mRNA 18951874
D013806 8353 HIST1H3E
H3.1
H3/d
H3FD
histone cluster 1, H3e [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of HIST1H3E protein affects cotreatment
/ increases expression
protein 18951874
D013806 8337 HIST2H2AA3
H2A
H2A.2
H2A/O
H2A/q
H2AFO
H2a-615
HIST2H2AA
histone cluster 2, H2aa3 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HIST2H2AA3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 121504 HIST4H4
H4/p
histone cluster 4, H4 Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Budesonide inhibits the reaction [IL1B protein results in increased acetylation of HIST4H4 protein]]] decreases reaction
/ increases acetylation
protein 18951874
D013806 81502 HM13
H13
IMP1
IMPAS
IMPAS-1
MSTP086
PSENL3
PSL3
SPP
SPPL1
dJ324O17.1
histocompatibility (minor) 13 Theophylline binds to HM13 protein affects binding
protein 18951874
D013806 3189 HNRNPH3
2H9
HNRPH3
heterogeneous nuclear ribonucleoprotein H3 (2H9) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HNRNPH3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 89781 HPS4
LE
Hermansky-Pudlak syndrome 4 Theophylline results in decreased expression of HPS4 mRNA decreases expression
mRNA 18951874
D013806 3306 HSPA2
HSP70-2
HSP70-3
heat shock 70kDa protein 2 Theophylline results in increased expression of HSPA2 mRNA increases expression
mRNA 16083514
D013806 27429 HTRA2
OMI
PARK13
PRSS25
HtrA serine peptidase 2 (EC:3.4.21.108) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HTRA2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 3364 HUS1
hHUS1
HUS1 checkpoint homolog (S. pombe) Theophylline results in decreased expression of HUS1 mRNA decreases expression
mRNA 18951874
D013806 3386 ICAM4
CD242
LW
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ICAM4 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 3425 IDUA
IDA
MPS1
iduronidase, alpha-L- (EC:3.2.1.76) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of IDUA protein affects cotreatment
/ decreases expression
protein 18951874
D013806 9592 IER2
ETR101
immediate early response 2 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of IER2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 3439 IFNA1
IFL
IFN
IFN-ALPHA
IFN-alphaD
IFNA13
IFNA@
interferon, alpha 1 IFNA1 protein results in decreased metabolism of Theophylline decreases metabolic processing
protein 9114909
D013806 3458 IFNG
IFG
IFI
interferon, gamma Theophylline results in decreased expression of IFNG mRNA decreases expression
mRNA 10596698
D013806 55764 IFT122
CED
CED1
SPG
WDR10
WDR10p
WDR140
intraflagellar transport 122 homolog (Chlamydomonas) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of IFT122 protein affects cotreatment
/ increases expression
protein 18951874
D013806 55081 IFT57
ESRRBL1
HIPPI
MHS4R2
intraflagellar transport 57 homolog (Chlamydomonas) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of IFT57 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 8100 IFT88
D13S1056E
DAF19
TG737
TTC10
hTg737
intraflagellar transport 88 homolog (Chlamydomonas) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of IFT88 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 3488 IGFBP5
IBP5
insulin-like growth factor binding protein 5 Theophylline results in decreased expression of IGFBP5 mRNA decreases expression
mRNA 16083514
D013806 3549 IHH
BDA1
HHG2
indian hedgehog Theophylline results in increased expression of IHH mRNA increases expression
mRNA 16083514
D013806 121457 IKBIP
IKIP
IKBKB interacting protein [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of IKBIP protein affects cotreatment
/ increases expression
protein 18951874
D013806 3592 IL12A
CLMF
IL-12A
NFSK
NKSF1
P35
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) Theophylline results in decreased expression of [IL12A protein binds to IL12B protein] affects binding
/ decreases expression
protein 15569413
D013806 3593 IL12B
CLMF
CLMF2
IL-12B
NKSF
NKSF2
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) Theophylline results in decreased expression of [IL12A protein binds to IL12B protein] affects binding
/ decreases expression
protein 15569413
D013806 3593 IL12B
CLMF
CLMF2
IL-12B
NKSF
NKSF2
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) Theophylline results in decreased expression of IL12B protein decreases expression
protein 15569413
D013806 3596 IL13
IL-13
P600
interleukin 13 Theophylline results in decreased expression of IL13 mRNA decreases expression
mRNA 16083514
D013806 3596 IL13
IL-13
P600
interleukin 13 Theophylline results in decreased expression of IL13 protein decreases expression
protein 16083514
D013806 3596 IL13
IL-13
P600
interleukin 13 Theophylline results in decreased secretion of IL13 protein decreases secretion
protein 16083514
D013806 3606 IL18
IGIF
IL-18
IL-1g
IL1F4
interleukin 18 (interferon-gamma-inducing factor) Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] decreases reaction
/ increases secretion
protein 18951874
D013806 3606 IL18
IGIF
IL-18
IL-1g
IL1F4
interleukin 18 (interferon-gamma-inducing factor) Theophylline inhibits the reaction [Tobacco Smoke Pollution inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] decreases reaction
/ increases secretion
protein 18951874
D013806 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta [Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 12070353
D013806 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Budesonide inhibits the reaction [IL1B protein results in increased acetylation of HIST4H4 protein]]] decreases reaction
/ increases acetylation
protein 18951874
D013806 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Theophylline promotes the reaction [Dexamethasone inhibits the reaction [Hydrogen Peroxide promotes the reaction [IL1B protein results in increased secretion of IL8 protein]]] decreases reaction
/ increases reaction
/ increases secretion
protein 15337792
D013806 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Theophylline promotes the reaction [IL1B protein results in increased secretion of CSF2 protein] increases reaction
/ increases secretion
protein 12070353
D013806 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta trichostatin A inhibits the reaction [[Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]] affects cotreatment
/ decreases reaction
/ increases secretion
protein 12070353
D013806 3559 IL2RA
CD25
IDDM10
IL2R
TCGFR
interleukin 2 receptor, alpha Theophylline results in decreased expression of IL2RA protein decreases expression
protein 1709825
D013806 3562 IL3
IL-3
MCGF
MULTI-CSF
interleukin 3 (colony-stimulating factor, multiple) Theophylline results in decreased expression of IL3 mRNA decreases expression
mRNA 10596698
D013806 3565 IL4
BCGF-1
BCGF1
BSF-1
BSF1
IL-4
interleukin 4 IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of MYC protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 8822937
D013806 3565 IL4
BCGF-1
BCGF1
BSF-1
BSF1
IL-4
interleukin 4 IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of TP53] affects cotreatment
/ decreases reaction
/ increases expression
protein 8822937
D013806 3565 IL4
BCGF-1
BCGF1
BSF-1
BSF1
IL-4
interleukin 4 IL4 protein inhibits the reaction [Theophylline results in decreased expression of BCL2 protein] decreases expression
/ decreases reaction
protein 8822937
D013806 3565 IL4
BCGF-1
BCGF1
BSF-1
BSF1
IL-4
interleukin 4 Theophylline results in decreased expression of IL4 mRNA decreases expression
mRNA 10596698
D013806 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) [Albuterol co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 20388727
D013806 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) [Bucladesine co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 20388727
D013806 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) [Dinoprostone co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 20388727
D013806 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) [Theophylline co-treated with Albuterol] inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 20388727
D013806 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Theophylline inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] decreases reaction
/ increases expression
mRNA 20388727
D013806 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Theophylline inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] decreases reaction
/ increases secretion
protein 20388727
D013806 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Theophylline inhibits the reaction [TNF protein results in increased expression of IL6 protein] decreases reaction
/ increases expression
protein 11770011
D013806 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Theophylline results in increased expression of IL6 mRNA increases expression
mRNA 16083514
D013806 3570 IL6R
CD126
IL-6R-1
IL-6RA
IL6Q
IL6RA
IL6RQ
gp80
interleukin 6 receptor Theophylline results in decreased expression of IL6R mRNA decreases expression
mRNA 18951874
D013806 3572 IL6ST
CD130
CDW130
GP130
IL-6RB
interleukin 6 signal transducer (gp130, oncostatin M receptor) Theophylline results in increased expression of IL6ST mRNA increases expression
mRNA 16083514
D013806 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 [Dexamethasone co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL8 protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 15337792
D013806 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 [Theophylline co-treated with Dexamethasone] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL8 protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 12070353
D013806 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Theophylline promotes the reaction [Dexamethasone inhibits the reaction [Hydrogen Peroxide promotes the reaction [IL1B protein results in increased secretion of IL8 protein]]] decreases reaction
/ increases reaction
/ increases secretion
protein 15337792
D013806 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Theophylline promotes the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL8 protein]] decreases reaction
/ increases reaction
/ increases secretion
protein 15337792
D013806 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Theophylline results in decreased expression of IL8 protein decreases expression
protein 12016098
D013806 3611 ILK
ILK-1
ILK-2
P59
p59ILK
integrin-linked kinase (EC:2.7.11.1) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ILK protein affects cotreatment
/ decreases expression
protein 18951874
D013806 58493 INIP
C9orf80
HSPC043
MISE
SOSSC
SSBIP1
hSSBIP1
INTS3 and NABP interacting protein [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of INIP protein affects cotreatment
/ decreases expression
protein 18951874
D013806 3665 IRF7
IRF-7H
IRF7A
IRF7B
IRF7C
IRF7H
interferon regulatory factor 7 Theophylline results in decreased expression of IRF7 mRNA decreases expression
mRNA 16083514
D013806 3667 IRS1
HIRS-1
insulin receptor substrate 1 Theophylline results in increased expression of IRS1 mRNA increases expression
mRNA 16083514
D013806 81533 ITFG1
TIP
integrin alpha FG-GAP repeat containing 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ITFG1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 3684 ITGAM
CD11B
CR3A
MAC-1
MAC1A
MO1A
SLEB6
integrin, alpha M (complement component 3 receptor 3 subunit) Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein]] decreases reaction
/ increases expression
/ increases reaction
protein 9762784
D013806 3684 ITGAM
CD11B
CR3A
MAC-1
MAC1A
MO1A
SLEB6
integrin, alpha M (complement component 3 receptor 3 subunit) Theophylline inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein] decreases reaction
/ increases expression
protein 9762784
D013806 3689 ITGB2
CD18
LAD
LCAMB
LFA-1
MAC-1
MF17
MFI7
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) Theophylline results in increased expression of ITGB2 mRNA increases expression
mRNA 16083514
D013806 9445 ITM2B
ABRI
BRI
BRI2
BRICD2B
E25B
E3-16
FBD
imBRI2
integral membrane protein 2B [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ITM2B protein affects cotreatment
/ increases expression
protein 18951874
D013806 79960 JADE1
PHF17
jade family PHD finger 1 Theophylline results in increased expression of JADE1 mRNA increases expression
mRNA 18951874
D013806 3716 JAK1
JAK1A
JAK1B
JTK3
Janus kinase 1 (EC:2.7.10.2) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of JAK1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 779446 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of JMJD3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 3748 KCNC3
KSHIIID
KV3.3
SCA13
potassium voltage-gated channel, Shaw-related subfamily, member 3 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of KCNC3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 27345 KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KCNMB4 protein affects cotreatment
/ increases expression
protein 18951874
D013806 23030 KDM4B
JMJD2B
TDRD14B
lysine (K)-specific demethylase 4B [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KDM4B protein affects cotreatment
/ increases expression
protein 18951874
D013806 450566 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KIAA1128 protein affects cotreatment
/ increases expression
protein 18951874
D013806 57587 KIAA1430 Theophylline results in increased expression of KIAA1430 mRNA increases expression
mRNA 18951874
D013806 459808 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KIAA1946 protein affects cotreatment
/ increases expression
protein 18951874
D013806 23095 KIF1B
CMT2
CMT2A
CMT2A1
HMSNII
KLP
NBLST1
kinesin family member 1B [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KIF1B protein affects cotreatment
/ increases expression
protein 18951874
D013806 22944 KIN
BTCD
KIN17
KIN, antigenic determinant of recA protein homolog (mouse) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KIN protein affects cotreatment
/ increases expression
protein 18951874
D013806 3804 KIR2DL3
CD158B2
CD158b
GL183
KIR-023GB
KIR-K7b
KIR-K7c
KIRCL23
NKAT
NKAT2
NKAT2A
NKAT2B
p58
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 Theophylline results in decreased expression of KIR2DL3 mRNA decreases expression
mRNA 18951874
D013806 55975 KLHL7
KLHL6
SBBI26
kelch-like family member 7 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of KLHL7 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 3915 LAMC1
LAMB2
laminin, gamma 1 (formerly LAMB2) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of LAMC1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 137994 LETM2
leucine zipper-EF-hand containing transmembrane protein 2 Theophylline results in decreased expression of LETM2 mRNA decreases expression
mRNA 18951874
D013806 10186 LHFP
lipoma HMGIC fusion partner (EC:3.6.5.4) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LHFP protein affects cotreatment
/ increases expression
protein 18951874
D013806 10186 LHFP
lipoma HMGIC fusion partner (EC:3.6.5.4) Theophylline results in decreased expression of LHFP mRNA decreases expression
mRNA 18951874
D013806 3984 LIMK1
LIMK
LIMK-1
LIM domain kinase 1 (EC:2.7.11.1) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LIMK1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 3991 LIPE
HSL
LHS
lipase, hormone-sensitive (EC:3.1.1.79) Theophylline inhibits the reaction [Epinephrine results in increased activity of LIPE protein] decreases reaction
/ increases activity
protein 7155675
D013806 3991 LIPE
HSL
LHS
lipase, hormone-sensitive (EC:3.1.1.79) Theophylline results in increased activity of LIPE protein increases activity
protein 7155675
D013806 4023 LPL
HDLCQ11
LIPD
lipoprotein lipase (EC:3.1.1.34) Theophylline results in increased expression of LPL mRNA increases expression
mRNA 16083514
D013806 10233 LRRC23
LRPB7
leucine rich repeat containing 23 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of LRRC23 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 566017 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of LSM8 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 7940 LST1
B144
D6S49E
LST-1
leukocyte specific transcript 1 Theophylline results in increased expression of LST1 mRNA increases expression
mRNA 16083514
D013806 4050 LTB
TNFC
TNFSF3
p33
lymphotoxin beta (TNF superfamily, member 3) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LTB protein affects cotreatment
/ increases expression
protein 18951874
D013806 4056 LTC4S
leukotriene C4 synthase (EC:4.4.1.20) Theophylline results in decreased secretion of LTC4S protein decreases secretion
protein 16083514
D013806 4057 LTF
GIG12
HLF2
LF
lactotransferrin Theophylline results in decreased expression of LTF protein decreases expression
protein 12016098
D013806 127018 LYPLAL1
lysophospholipase-like 1 (EC:3.1.2.-) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LYPLAL1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 93487 MAPK1IP1L
C14orf32
MISS
c14_5346
mitogen-activated protein kinase 1 interacting protein 1-like [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of MAPK1IP1L protein affects cotreatment
/ increases expression
protein 18951874
D013806 5598 MAPK7
BMK1
ERK4
ERK5
PRKM7
mitogen-activated protein kinase 7 (EC:2.7.11.24) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MAPK7 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 4190 MDH1
MDH-s
MDHA
MGC:1375
MOR2
malate dehydrogenase 1, NAD (soluble) (EC:1.1.1.37 1.1.1.96) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of MDH1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 23389 MED13L
PROSIT240
THRAP2
TRAP240L
mediator complex subunit 13-like [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of MED13L protein affects cotreatment
/ increases expression
protein 18951874
D013806 10025 MED16
DRIP92
THRAP5
TRAP95
mediator complex subunit 16 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MED16 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 4205 MEF2A
ADCAD1
RSRFC4
RSRFC9
mef2
myocyte enhancer factor 2A Theophylline results in decreased expression of MEF2A mRNA decreases expression
mRNA 18951874
D013806 196074 METTL15
METT5D1
methyltransferase like 15 (EC:2.1.1.-) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of METTL15 protein affects cotreatment
/ increases expression
protein 18951874
D013806 10227 MFSD10
TETRAN
TETTRAN
major facilitator superfamily domain containing 10 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MFSD10 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 4258 MGST2
GST2
MGST-II
microsomal glutathione S-transferase 2 (EC:2.5.1.18) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MGST2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 284021 MILR1
Allergin-1
C17orf60
MCA-32
MCA32
mast cell immunoglobulin-like receptor 1 Theophylline results in decreased expression of MILR1 mRNA decreases expression
mRNA 18951874
D013806 79682 CENPU
CENP50
CENPU50
KLIP1
MLF1IP
PBIP1
centromere protein U [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MLF1IP protein affects cotreatment
/ decreases expression
protein 18951874
D013806 326625 MMAB
ATR
cblB
cob
methylmalonic aciduria (cobalamin deficiency) cblB type (EC:2.5.1.17) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MMAB protein affects cotreatment
/ decreases expression
protein 18951874
D013806 22879 MON1B
HSRG1
SAND2
SRG1
MON1 secretory trafficking family member B Theophylline results in decreased expression of MON1B mRNA decreases expression
mRNA 18951874
D013806 10200 MPHOSPH6
MPP
MPP-6
MPP6
M-phase phosphoprotein 6 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MPHOSPH6 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 4353 MPO
myeloperoxidase (EC:1.11.2.2) Theophylline results in decreased expression of MPO protein decreases expression
protein 12016098
D013806 26164 MTG2
GTPBP5
ObgH1
dJ1005F21.2
mitochondrial ribosome-associated GTPase 2 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MTG2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 219402 MTIF3
IF3mt
mitochondrial translational initiation factor 3 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MTIF3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 25821 MTO1
COXPD10
mitochondrial tRNA translation optimization 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MTO1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 727897 MUC5B
MG1
MUC-5B
MUC5
MUC9
mucin 5B, oligomeric mucus/gel-forming Theophylline results in decreased expression of MUC5B mRNA decreases expression
mRNA 16083514
D013806 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of MYC protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 8822937
D013806 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog Theophylline affects the expression of MYC mRNA affects expression
mRNA 8822937
D013806 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog [Theophylline co-treated with Chlorambucil] results in increased expression of MYC protein affects cotreatment
/ increases expression
protein 8822937
D013806 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog Theophylline results in decreased expression of MYC mRNA decreases expression
mRNA 8416737
D013806 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog Theophylline results in increased expression of MYC mRNA mutant form increases expression
mRNA 8416737
D013806 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog Theophylline results in increased expression of MYC protein increases expression
protein 8822937
D013806 80179 MYO19
MYOHD1
myosin XIX [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MYO19 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 440145 MZT1
C13orf37
MOZART1
mitotic spindle organizing protein 1 Theophylline results in decreased expression of MZT1 mRNA decreases expression
mRNA 18951874
D013806 10443 N4BP2L2
92M18.3
CG005
PFAAP5
NEDD4 binding protein 2-like 2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of N4BP2L2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 138151 NACC2
BEND9
BTBD14
BTBD14A
BTBD31
RBB
NACC family member 2, BEN and BTB (POZ) domain containing Theophylline results in increased expression of NACC2 mRNA increases expression
mRNA 18951874
D013806 222236 NAPEPLD
FMP30
NAPE-PLD
N-acyl phosphatidylethanolamine phospholipase D (EC:3.1.4.54) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NAPEPLD protein affects cotreatment
/ increases expression
protein 18951874
D013806 79664 NARG2
BRCC1
NMDA receptor regulated 2 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of NARG2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 65065 NBEAL1
A530083I02Rik
ALS2CR16
ALS2CR17
neurobeachin-like 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of NBEAL1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 8440 NCK2
GRB4
NCKbeta
NCK adaptor protein 2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NCK2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 4708 NDUFB2
AGGG
CI-AGGG
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa (EC:1.6.5.3 1.6.99.3) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of NDUFB2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 23327 NEDD4L
NEDD4-2
NEDD4.2
RSP5
hNEDD4-2
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (EC:6.3.2.-) Theophylline results in increased expression of NEDD4L mRNA increases expression
mRNA 16083514
D013806 4790 NFKB1
EBP-1
KBF1
NF-kB1
NF-kappa-B
NF-kappaB
NFKB-p105
NFKB-p50
NFkappaB
p105
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Theophylline inhibits the reaction [TNF protein affects the localization of NFKB1 protein] affects localization
/ decreases reaction
protein 10344522
D013806 4792 NFKBIA
IKBA
MAD-3
NFKBI
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha Theophylline affects the expression of NFKBIA protein affects expression
protein 12065913
D013806 4792 NFKBIA
IKBA
MAD-3
NFKBI
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha Theophylline results in decreased degradation of NFKBIA protein decreases degradation
protein 11770011
D013806 51701 NLK
nemo-like kinase (EC:2.7.11.24) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NLK protein affects cotreatment
/ increases expression
protein 18951874
D013806 23530 NNT
GCCD4
nicotinamide nucleotide transhydrogenase (EC:1.6.1.2) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NNT protein affects cotreatment
/ increases expression
protein 18951874
D013806 100301851 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of NOLA3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 23420 NOMO1
Nomo
PM5
NODAL modulator 1 Theophylline binds to NOMO1 protein affects binding
protein 18951874
D013806 4835 NQO2
DHQV
DIA6
NMOR2
QR2
NAD(P)H dehydrogenase, quinone 2 (EC:1.10.99.2) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of NQO2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 9315 NREP
C5orf13
D4S114
P311
PRO1873
PTZ17
SEZ17
neuronal regeneration related protein Theophylline results in decreased expression of NREP mRNA decreases expression
mRNA 18951874
D013806 9369 NRXN3
C14orf60
neurexin 3 Theophylline results in increased expression of NRXN3 mRNA increases expression
mRNA 16083514
D013806 387338 NSUN4
RP4-603I14.2
SHTAP
NOP2/Sun domain family, member 4 Theophylline results in increased expression of NSUN4 mRNA increases expression
mRNA 18951874
D013806 10762 NUP50
NPAP60
NPAP60L
nucleoporin 50kDa [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NUP50 protein affects cotreatment
/ increases expression
protein 18951874
D013806 10204 NUTF2
NTF2
PP15
nuclear transport factor 2 Theophylline results in increased expression of NUTF2 mRNA increases expression
mRNA 16083514
D013806 54940 OCIAD1
ASRIJ
OCIA
TPA018
OCIA domain containing 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of OCIAD1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 283694 OR4N4
OR15-1
OR15-5
olfactory receptor, family 4, subfamily N, member 4 Theophylline results in increased expression of OR4N4 mRNA increases expression
mRNA 18951874
D013806 5007 OSBP
OSBP1
oxysterol binding protein Theophylline results in increased expression of OSBP mRNA increases expression
mRNA 16083514
D013806 23440 OTP
orthopedia homeobox [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of OTP protein affects cotreatment
/ decreases expression
protein 18951874
D013806 23440 OTP
orthopedia homeobox [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of OTP protein affects cotreatment
/ increases expression
protein 18951874
D013806 255967 PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) (EC:3.1.13.4) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PAN3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) Theophylline binds to PARP1 protein affects binding
protein 18951874
D013806 100301806 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PB1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 654790 PCP4L1
IQM1
Purkinje cell protein 4 like 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PCP4L1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 5125 PCSK5
PC5
PC6
PC6A
SPC6
subtilase
proprotein convertase subtilisin/kexin type 5 (EC:3.4.21.-) Theophylline results in increased expression of PCSK5 mRNA increases expression
mRNA 16083514
D013806 57107 PDSS2
C6orf210
COQ10D3
DLP1
bA59I9.3
hDLP1
prenyl (decaprenyl) diphosphate synthase, subunit 2 (EC:2.5.1.91) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PDSS2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 8682 PEA15
HMAT1
HUMMAT1H
MAT1
MAT1H
PEA-15
PED
phosphoprotein enriched in astrocytes 15 Theophylline results in decreased expression of PEA15 mRNA decreases expression
mRNA 16083514
D013806 5191 PEX7
PBD9B
PTS2R
RCDP1
RD
peroxisomal biogenesis factor 7 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PEX7 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 8554 PIAS1
DDXBP1
GBP
GU/RH-II
ZMIZ3
protein inhibitor of activated STAT, 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PIAS1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 9063 PIAS2
ARIP3
DIP
MIZ
MIZ1
PIASX
PIASX-ALPHA
PIASX-BETA
SIZ2
ZMIZ4
protein inhibitor of activated STAT, 2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PIAS2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 8301 PICALM
CALM
CLTH
LAP
phosphatidylinositol binding clathrin assembly protein [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PICALM protein affects cotreatment
/ increases expression
protein 18951874
D013806 5279 PIGC
GPI2
phosphatidylinositol glycan anchor biosynthesis, class C (EC:2.4.1.198) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PIGC protein affects cotreatment
/ increases expression
protein 18951874
D013806 51268 PIPOX
LPIPOX
pipecolic acid oxidase (EC:1.5.3.1 1.5.3.7) Theophylline results in decreased expression of PIPOX mRNA decreases expression
mRNA 18951874
D013806 23760 PITPNB
PI-TP-beta
PtdInsTP
VIB1B
phosphatidylinositol transfer protein, beta [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PITPNB protein affects cotreatment
/ increases expression
protein 18951874
D013806 5314 PKHD1
ARPKD
FCYT
TIGM1
polycystic kidney and hepatic disease 1 (autosomal recessive) Theophylline results in decreased expression of PKHD1 mRNA decreases expression
mRNA 18951874
D013806 23646 PLD3
HU-K4
HUK4
phospholipase D family, member 3 (EC:3.1.4.4) Theophylline results in increased expression of PLD3 mRNA increases expression
mRNA 16083514
D013806 59338 PLEKHA1
TAPP1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PLEKHA1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 5356 PLRG1
Cwc1
PRL1
PRP46
PRPF46
TANGO4
pleiotropic regulator 1 Theophylline results in increased expression of PLRG1 mRNA increases expression
mRNA 18951874
D013806 84172 POLR1B
RPA135
RPA2
Rpo1-2
polymerase (RNA) I polypeptide B, 128kDa (EC:2.7.7.6) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of POLR1B protein affects cotreatment
/ increases expression
protein 18951874
D013806 5435 POLR2F
HRBP14.4
POLRF
RPABC2
RPB14.4
RPB6
polymerase (RNA) II (DNA directed) polypeptide F (EC:2.7.7.6) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of POLR2F protein affects cotreatment
/ decreases expression
protein 18951874
D013806 171568 POLR3H
RPC22.9
RPC8
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) (EC:2.7.7.6) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of POLR3H protein affects cotreatment
/ decreases expression
protein 18951874
D013806 51728 POLR3K
C11
C11-RNP3
RPC10
RPC11
RPC12.5
hRPC11
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of POLR3K protein affects cotreatment
/ decreases expression
protein 18951874
D013806 5465 PPARA
NR1C1
PPAR
PPARalpha
hPPAR
peroxisome proliferator-activated receptor alpha [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PPARA protein affects cotreatment
/ decreases expression
protein 18951874
D013806 5468 PPARG
CIMT1
GLM1
NR1C3
PPARG1
PPARG2
PPARgamma
peroxisome proliferator-activated receptor gamma Theophylline results in increased expression of PPARG mRNA increases expression
mRNA 16569937
D013806 5468 PPARG
CIMT1
GLM1
NR1C3
PPARG1
PPARG2
PPARgamma
peroxisome proliferator-activated receptor gamma Theophylline results in increased expression of PPARG protein increases expression
protein 16569937
D013806 5515 PPP2CA
PP2Ac
PP2CA
PP2Calpha
RP-C
protein phosphatase 2, catalytic subunit, alpha isozyme (EC:3.1.3.16) Theophylline results in decreased expression of PPP2CA mRNA decreases expression
mRNA 16083514
D013806 5532 PPP3CB
CALNA2
CALNB
CNA2
PP2Bbeta
protein phosphatase 3, catalytic subunit, beta isozyme (EC:3.1.3.16) Theophylline results in decreased expression of PPP3CB mRNA decreases expression
mRNA 16083514
D013806 5558 PRIM2
PRIM2A
p58
primase, DNA, polypeptide 2 (58kDa) (EC:2.7.7.-) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PRIM2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 5562 PRKAA1
AMPK
AMPKa1
protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31) Theophylline results in decreased expression of PRKAA1 mRNA decreases expression
mRNA 18951874
D013806 5566 PRKACA
PKACA
protein kinase, cAMP-dependent, catalytic, alpha (EC:2.7.11.11) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PRKACA protein affects cotreatment
/ decreases expression
protein 18951874
D013806 5578 PRKCA
AAG6
PKC-alpha
PKCA
PRKACA
protein kinase C, alpha (EC:2.7.11.13) Theophylline results in decreased expression of PRKCA mRNA decreases expression
mRNA 16083514
D013806 8575 PRKRA
DYT16
PACT
RAX
protein kinase, interferon-inducible double stranded RNA dependent activator [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PRKRA protein affects cotreatment
/ increases expression
protein 18951874
D013806 5618 PRLR
hPRLrI
prolactin receptor [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PRLR protein affects cotreatment
/ decreases expression
protein 18951874
D013806 55119 PRPF38B
NET1
RP11-293A10.1
pre-mRNA processing factor 38B [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PRPF38B protein affects cotreatment
/ increases expression
protein 18951874
D013806 7803 PTP4A1
HH72
PRL-1
PRL1
PTP(CAAX1)
PTPCAAX1
protein tyrosine phosphatase type IVA, member 1 (EC:3.1.3.48) Theophylline results in decreased expression of PTP4A1 mRNA decreases expression
mRNA 16083514
D013806 5771 PTPN2
PTN2
PTPT
TC-PTP
TCELLPTP
TCPTP
protein tyrosine phosphatase, non-receptor type 2 (EC:3.1.3.48) Theophylline results in increased expression of PTPN2 mRNA increases expression
mRNA 18951874
D013806 5791 PTPRE
HPTPE
PTPE
R-PTP-EPSILON
protein tyrosine phosphatase, receptor type, E (EC:3.1.3.48) Theophylline results in increased expression of PTPRE mRNA increases expression
mRNA 18951874
D013806 29920 PYCR2
P5CR2
pyrroline-5-carboxylate reductase family, member 2 (EC:1.5.1.2) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PYCR2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 9230 RAB11B
H-YPT3
RAB11B, member RAS oncogene family Theophylline results in increased expression of RAB11B mRNA increases expression
mRNA 18951874
D013806 23011 RAB21
RAB21, member RAS oncogene family [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RAB21 protein affects cotreatment
/ increases expression
protein 18951874
D013806 5883 RAD9A
RAD9
RAD9 homolog A (S. pombe) (EC:3.1.11.2) Theophylline results in decreased expression of RAD9A mRNA decreases expression
mRNA 16083514
D013806 29098 RANGRF
HSPC236
MOG1
RANGNRF
RAN guanine nucleotide release factor Theophylline results in increased expression of RANGRF mRNA increases expression
mRNA 18951874
D013806 9462 RASAL2
NGAP
RAS protein activator like 2 Theophylline results in decreased expression of RASAL2 mRNA decreases expression
mRNA 18951874
D013806 5925 RB1
OSRC
RB
p105-Rb
pRb
pp110
retinoblastoma 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RB1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 9939 RBM8A
BOV-1A
BOV-1B
BOV-1C
C1DELq21.1
DEL1q21.1
MDS014
RBM8
RBM8B
TAR
Y14
ZNRP
ZRNP1
RNA binding motif protein 8A [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RBM8A protein affects cotreatment
/ decreases expression
protein 18951874
D013806 149041 RC3H1
RNF198
ROQUIN
ring finger and CCCH-type domains 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RC3H1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 1827 RCAN1
ADAPT78
CSP1
DSC1
DSCR1
MCIP1
RCN1
regulator of calcineurin 1 Theophylline results in increased expression of RCAN1 mRNA increases expression
mRNA 16083514
D013806 157506 RDH10
SDR16C4
retinol dehydrogenase 10 (all-trans) (EC:1.1.1.300) Theophylline results in increased expression of RDH10 mRNA increases expression
mRNA 18951874
D013806 8434 RECK
ST15
reversion-inducing-cysteine-rich protein with kazal motifs [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RECK protein affects cotreatment
/ decreases expression
protein 18951874
D013806 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Theophylline affects the localization of RELA protein affects localization
protein 11770011
D013806 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Theophylline inhibits the reaction [TNF protein results in increased expression of RELA protein] decreases reaction
/ increases expression
protein 11770011
D013806 5972 REN
HNFJ2
renin (EC:3.4.23.15) Theophylline affects the expression of REN protein affects expression
protein 7743391
D013806 55312 RFK
RIFK
riboflavin kinase (EC:2.7.1.26) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RFK protein affects cotreatment
/ decreases expression
protein 18951874
D013806 23180 RFTN1
PIB10
PIG9
RAFTLIN
raftlin, lipid raft linker 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RFTN1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 431530 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RFXDC2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 6004 RGS16
A28-RGS14
A28-RGS14P
RGS-R
regulator of G-protein signaling 16 Theophylline results in increased expression of RGS16 mRNA increases expression
mRNA 16083514
D013806 83695 RHNO1
C12orf32
RHINO
RAD9-HUS1-RAD1 interacting nuclear orphan 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RHNO1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 89941 RHOT2
ARHT2
C16orf39
MIRO-2
MIRO2
RASL
ras homolog family member T2 (EC:3.6.5.-) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RHOT2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 79608 RIC3
AYST720
PRO1385
RIC3 acetylcholine receptor chaperone Theophylline binds to RIC3 protein affects binding
protein 18951874
D013806 8780 RIOK3
SUDD
RIO kinase 3 (EC:2.7.11.1) Theophylline results in decreased expression of RIOK3 mRNA decreases expression
mRNA 16083514
D013806 11035 RIPK3
RIP3
receptor-interacting serine-threonine kinase 3 (EC:2.7.11.1) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RIPK3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 64795 RMND5A
CTLH
GID2
GID2A
RMD5
p44CTLH
required for meiotic nuclear division 5 homolog A (S. cerevisiae) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RMND5A protein affects cotreatment
/ increases expression
protein 18951874
D013806 8635 RNASET2
RNASE6PL
bA514O12.3
ribonuclease T2 (EC:3.1.27.1) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RNASET2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 6209 RPS15
RIG
S15
ribosomal protein S15 Theophylline results in decreased expression of RPS15 mRNA decreases expression
mRNA 18951874
D013806 157869 SBSPON
C8orf84
RPESP
somatomedin B and thrombospondin, type 1 domain containing Theophylline results in decreased expression of SBSPON mRNA decreases expression
mRNA 18951874
D013806 9997 SCO2
CEMCOX1
MYP6
SCO1L
SCO2 cytochrome c oxidase assembly protein [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of SCO2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 10993 SDS
SDH
serine dehydratase (EC:4.3.1.17 4.3.1.19) Theophylline results in increased expression of SDS mRNA increases expression
mRNA 16083514
D013806 79048 SECISBP2
SBP2
SECIS binding protein 2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SECISBP2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 6402 SELL
CD62L
LAM1
LECAM1
LEU8
LNHR
LSEL
LYAM1
PLNHR
TQ1
selectin L Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased secretion of SELL protein]] decreases reaction
/ increases reaction
/ increases secretion
protein 9762784
D013806 6402 SELL
CD62L
LAM1
LECAM1
LEU8
LNHR
LSEL
LYAM1
PLNHR
TQ1
selectin L Theophylline inhibits the reaction [Platelet Activating Factor results in increased secretion of SELL protein] decreases reaction
/ increases secretion
protein 9762784
D013806 5265 SERPINA1
A1A
A1AT
AAT
PI
PI1
PRO2275
alpha1AT
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 SERPINA1 gene affects the susceptibility to Theophylline affects response to substance
gene 17943569
D013806 29072 SETD2
HBP231
HIF-1
HIP-1
HYPB
KMT3A
SET2
p231HBP
SET domain containing 2 (EC:2.1.1.43) Theophylline results in decreased expression of SETD2 mRNA decreases expression
mRNA 18951874
D013806 6439 SFTPB
PSP-B
SFTB3
SFTP3
SMDP1
SP-B
surfactant protein B [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SFTPB protein affects cotreatment
/ increases expression
protein 18951874
D013806 9047 SH2D2A
F2771
SCAP
TSAD
VRAP
SH2 domain containing 2A [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of SH2D2A protein affects cotreatment
/ decreases expression
protein 18951874
D013806 57630 SH3RF1
POSH
RNF142
SH3MD2
SH3 domain containing ring finger 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SH3RF1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 257218 SHPRH
bA545I5.2
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SHPRH protein affects cotreatment
/ increases expression
protein 18951874
D013806 100195279 Theophylline results in increased expression of SIKE mRNA increases expression
mRNA 18951874
D013806 22933 SIRT2
SIR2
SIR2L
SIR2L2
sirtuin 2 (EC:3.5.1.-) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of SIRT2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 84561 SLC12A8
CCC9
solute carrier family 12, member 8 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SLC12A8 protein affects cotreatment
/ increases expression
protein 18951874
D013806 56996 SLC12A9
CCC6
CIP1
WO3.3
hCCC6
solute carrier family 12, member 9 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of SLC12A9 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 6566 SLC16A1
HHF7
MCT
MCT1
solute carrier family 16 (monocarboxylate transporter), member 1 Theophylline inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates] decreases reaction
/ increases uptake
protein 19023563
D013806 29957 SLC25A24
APC1
SCAMC-1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SLC25A24 protein affects cotreatment
/ increases expression
protein 18951874
D013806 55334 SLC39A9
ZIP-9
ZIP9
solute carrier family 39, member 9 Theophylline results in increased expression of SLC39A9 mRNA increases expression
mRNA 18951874
D013806 6528 SLC5A5
NIS
TDH1
solute carrier family 5 (sodium/iodide cotransporter), member 5 Theophylline results in increased expression of SLC5A5 protein increases expression
protein 19409042
D013806 7871 SLMAP
SLAP
sarcolemma associated protein [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SLMAP protein affects cotreatment
/ increases expression
protein 18951874
D013806 4087 SMAD2
JV18
JV18-1
MADH2
MADR2
hMAD-2
hSMAD2
SMAD family member 2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SMAD2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 4090 SMAD5
DWFC
JV5-1
MADH5
SMAD family member 5 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SMAD5 protein affects cotreatment
/ increases expression
protein 18951874
D013806 57223 SMEK2
FLFL2
PP4R3B
PSY2
smk1
SMEK homolog 2, suppressor of mek1 (Dictyostelium) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of SMEK2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 79086 SMIM7
C19orf42
small integral membrane protein 7 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of SMIM7 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 55234 SMU1
BWD
RP11-54K16.3
SMU-1
fSAP57
smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) Theophylline results in increased expression of SMU1 mRNA increases expression
mRNA 18951874
D013806 8773 SNAP23
HsT17016
SNAP-23
SNAP23A
SNAP23B
synaptosomal-associated protein, 23kDa [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SNAP23 protein affects cotreatment
/ increases expression
protein 18951874
D013806 724102 SNHG4
NCRNA00059
U19H
small nucleolar RNA host gene 4 (non-protein coding) Theophylline results in increased expression of SNHG4 mRNA increases expression
mRNA 18951874
D013806 23161 SNX13
RGS-PX1
sorting nexin 13 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SNX13 protein affects cotreatment
/ increases expression
protein 18951874
D013806 26010 SPATS2L
DNAPTP6
SGNP
spermatogenesis associated, serine-rich 2-like Theophylline results in decreased expression of SPATS2L mRNA decreases expression
mRNA 18951874
D013806 63826 SRR
ILV1
ISO1
serine racemase (EC:4.3.1.17 5.1.1.18 4.3.1.18) Theophylline results in decreased expression of SRR mRNA decreases expression
mRNA 18951874
D013806 6428 SRSF3
SFRS3
SRp20
serine/arginine-rich splicing factor 3 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SRSF3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 6745 SSR1
TRAPA
signal sequence receptor, alpha Theophylline results in decreased expression of SSR1 mRNA decreases expression
mRNA 16083514
D013806 6747 SSR3
TRAPG
signal sequence receptor, gamma (translocon-associated protein gamma) Theophylline results in increased expression of SSR3 mRNA increases expression
mRNA 18951874
D013806 6750 SST
SMST
somatostatin Theophylline results in increased secretion of SST protein increases secretion
protein 16601281
D013806 6487 ST3GAL3
EIEE15
MRT12
SIAT6
ST3GALII
ST3GalIII
ST3N
ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (EC:2.4.99.6) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ST3GAL3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 10254 STAM2
Hbp
STAM2A
STAM2B
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of STAM2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 6774 STAT3
APRF
HIES
signal transducer and activator of transcription 3 (acute-phase response factor) Theophylline results in increased expression of STAT3 mRNA increases expression
mRNA 16083514
D013806 8428 STK24
MST3
MST3B
STE20
STK3
serine/threonine kinase 24 (EC:2.7.11.1) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of STK24 protein affects cotreatment
/ increases expression
protein 18951874
D013806 140901 STK35
CLIK1
STK35L1
serine/threonine kinase 35 (EC:2.7.11.1) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of STK35 protein affects cotreatment
/ increases expression
protein 18951874
D013806 692637 Theophylline results in decreased expression of SUI1 mRNA decreases expression
mRNA 16083514
D013806 6830 SUPT6H
SPT6
SPT6H
emb-5
suppressor of Ty 6 homolog (S. cerevisiae) Theophylline results in decreased expression of SUPT6H mRNA decreases expression
mRNA 16083514
D013806 440423 SUZ12P1
SUZ12P
suppressor of zeste 12 homolog pseudogene 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SUZ12P1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 6863 TAC1
Hs.2563
NK2
NKNA
NPK
TAC2
tachykinin, precursor 1 Theophylline inhibits the reaction [TAC1 protein results in increased secretion of Histamine] decreases reaction
/ increases secretion
protein 1707400
D013806 9015 TAF1A
MGC:17061
RAFI48
SL1
TAFI48
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa Theophylline results in increased expression of TAF1A mRNA increases expression
mRNA 18951874
D013806 6879 TAF7
TAF2F
TAFII55
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa Theophylline results in decreased expression of TAF7 mRNA decreases expression
mRNA 16083514
D013806 80222 TARS2
TARSL1
thrRS
threonyl-tRNA synthetase 2, mitochondrial (putative) (EC:6.1.1.3) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TARS2 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 50840 TAS2R14
T2R14
TRB1
taste receptor, type 2, member 14 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TAS2R14 protein affects cotreatment
/ increases expression
protein 18951874
D013806 6902 TBCA
tubulin folding cofactor A Theophylline results in increased expression of TBCA mRNA increases expression
mRNA 18951874
D013806 6916 TBXAS1
BDPLT14
CYP5
CYP5A1
GHOSAL
THAS
TS
TXAS
TXS
thromboxane A synthase 1 (platelet) (EC:5.3.99.5) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TBXAS1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 6929 TCF3
E2A
E47
ITF1
TCF-3
VDIR
bHLHb21
transcription factor 3 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TCF3 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 6948 TCN2
D22S676
D22S750
II
TC
TC_II
TC-2
TC2
TCII
transcobalamin II Theophylline results in increased expression of TCN2 mRNA increases expression
mRNA 16083514
D013806 79736 TEFM
C17orf42
transcription elongation factor, mitochondrial [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TEFM protein affects cotreatment
/ increases expression
protein 18951874
D013806 7016 TESK1
testis-specific kinase 1 (EC:2.7.12.1) Theophylline results in increased expression of TESK1 mRNA increases expression
mRNA 16083514
D013806 7040 TGFB1
CED
DPD1
LAP
TGFB
TGFbeta
transforming growth factor, beta 1 Theophylline inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] decreases reaction
/ increases expression
protein 16430859
D013806 7040 TGFB1
CED
DPD1
LAP
TGFB
TGFbeta
transforming growth factor, beta 1 Theophylline inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] decreases reaction
/ increases expression
protein 16430859
D013806 7040 TGFB1
CED
DPD1
LAP
TGFB
TGFbeta
transforming growth factor, beta 1 Theophylline promotes the reaction [Dexamethasone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]] decreases reaction
/ increases expression
/ increases reaction
protein 16430859
D013806 7050 TGIF1
HPE4
TGIF
TGFB-induced factor homeobox 1 Theophylline results in increased expression of TGIF1 mRNA increases expression
mRNA 16083514
D013806 79838 TMC5
transmembrane channel-like 5 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TMC5 protein affects cotreatment
/ increases expression
protein 18951874
D013806 222068 TMED4
ERS25
HNLF
transmembrane emp24 protein transport domain containing 4 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TMED4 protein affects cotreatment
/ increases expression
protein 18951874
D013806 54664 TMEM106B
transmembrane protein 106B [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TMEM106B protein affects cotreatment
/ increases expression
protein 18951874
D013806 55266 TMEM19
transmembrane protein 19 Theophylline results in decreased expression of TMEM19 mRNA decreases expression
mRNA 18951874
D013806 79161 TMEM243
C7orf23
MM-TRAG
transmembrane protein 243, mitochondrial [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TMEM243 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 54916 TMEM260
C14orf101
transmembrane protein 260 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TMEM260 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 9725 TMEM63A
KIAA0792
transmembrane protein 63A Theophylline results in decreased expression of TMEM63A mRNA decreases expression
mRNA 18951874
D013806 283232 TMEM80
transmembrane protein 80 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TMEM80 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 84910 TMEM87B
transmembrane protein 87B [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TMEM87B protein affects cotreatment
/ increases expression
protein 18951874
D013806 54495 TMX3
PDIA13
TXNDC10
thioredoxin-related transmembrane protein 3 (EC:5.3.4.1) Theophylline results in increased expression of TMX3 mRNA increases expression
mRNA 18951874
D013806 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor [Albuterol co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 20388727
D013806 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Albuterol promotes the reaction [Theophylline inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]] decreases reaction
/ increases reaction
/ increases secretion
protein 20388727
D013806 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] decreases reaction
/ increases secretion
protein 18951874
D013806 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Theophylline inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] decreases reaction
/ increases expression
mRNA 8162974
20388727
D013806 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Theophylline inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] decreases reaction
/ increases secretion
protein 8162974
D013806 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Theophylline inhibits the reaction [TNF protein affects the localization of NFKB1 protein] affects localization
/ decreases reaction
protein 10344522
D013806 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Theophylline inhibits the reaction [TNF protein results in increased expression of IL6 protein] decreases reaction
/ increases expression
protein 11770011
D013806 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Theophylline inhibits the reaction [TNF protein results in increased expression of RELA protein] decreases reaction
/ increases expression
protein 11770011
D013806 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Theophylline inhibits the reaction [Tobacco Smoke Pollution inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] decreases reaction
/ increases secretion
protein 18951874
D013806 25816 TNFAIP8
GG2-1
MDC-3.13
NDED
SCC-S2
SCCS2
tumor necrosis factor, alpha-induced protein 8 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TNFAIP8 protein affects cotreatment
/ increases expression
protein 18951874
D013806 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of TP53] affects cotreatment
/ decreases reaction
/ increases expression
8822937
D013806 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 [Theophylline co-treated with Chlorambucil] results in increased expression of TP53 affects cotreatment
/ increases expression
8822937
D013806 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Theophylline results in decreased expression of TP53 decreases expression
8822937
D013806 7172 TPMT
thiopurine S-methyltransferase (EC:2.1.1.67) Theophylline results in increased expression of TPMT mRNA increases expression
mRNA 16083514
D013806 7174 TPP2
TPP-2
tripeptidyl peptidase II (EC:3.4.14.10) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TPP2 protein affects cotreatment
/ increases expression
protein 18951874
D013806 7185 TRAF1
EBI6
MGC:10353
TNF receptor-associated factor 1 Theophylline results in decreased expression of TRAF1 mRNA decreases expression
mRNA 16083514
D013806 89122 TRIM4
RNF87
tripartite motif containing 4 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TRIM4 protein affects cotreatment
/ increases expression
protein 18951874
D013806 93587 TRMT10A
RG9MTD2
TRM10
tRNA methyltransferase 10 homolog A (S. cerevisiae) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TRMT10A protein affects cotreatment
/ increases expression
protein 18951874
D013806 93587 TRMT10A
RG9MTD2
TRM10
tRNA methyltransferase 10 homolog A (S. cerevisiae) Theophylline results in decreased expression of TRMT10A mRNA decreases expression
mRNA 18951874
D013806 54482 TRMT13
CCDC76
tRNA methyltransferase 13 homolog (S. cerevisiae) (EC:2.1.1.225) Theophylline results in increased expression of TRMT13 mRNA increases expression
mRNA 18951874
D013806 115708 TRMT61A
C14orf172
GCD14
Gcd14p
TRM61
hTRM61
tRNA methyltransferase 61 homolog A (S. cerevisiae) (EC:2.1.1.220) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TRMT61A protein affects cotreatment
/ decreases expression
protein 18951874
D013806 54822 TRPM7
ALSPDC
CHAK
CHAK1
LTRPC7
TRP-PLIK
transient receptor potential cation channel, subfamily M, member 7 (EC:2.7.11.1) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TRPM7 protein affects cotreatment
/ increases expression
protein 18951874
D013806 7267 TTC3
DCRR1
RNF105
TPRDIII
tetratricopeptide repeat domain 3 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TTC3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 9652 TTC37
KIAA0372
Ski3
tetratricopeptide repeat domain 37 Theophylline results in decreased expression of TTC37 mRNA decreases expression
mRNA 18951874
D013806 26140 TTLL3
HOTTL
tubulin tyrosine ligase-like family, member 3 Theophylline binds to TTLL3 protein affects binding
protein 18951874
D013806 7273 TTN
CMD1G
CMH9
CMPD4
EOMFC
HMERF
LGMD2J
MYLK5
TMD
titin (EC:2.7.11.1) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TTN protein affects cotreatment
/ increases expression
protein 18951874
D013806 10376 TUBA1B
K-ALPHA-1
tubulin, alpha 1b [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TUBA1B protein affects cotreatment
/ decreases expression
protein 18951874
D013806 51174 TUBD1
TUBD
tubulin, delta 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TUBD1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 7991 TUSC3
D8S1992
M33
MRT22
MRT7
N33
OST3A
tumor suppressor candidate 3 Theophylline results in increased expression of TUSC3 mRNA increases expression
mRNA 16083514
D013806 56061 UBFD1
UBPH
ubiquitin family domain containing 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of UBFD1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 29978 UBQLN2
ALS15
CHAP1
DSK2
N4BP4
PLIC2
ubiquilin 2 Theophylline results in increased expression of UBQLN2 mRNA increases expression
mRNA 16083514
D013806 7343 UBTF
NOR-90
UBF
UBF-1
UBF1
upstream binding transcription factor, RNA polymerase I [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of UBTF protein affects cotreatment
/ decreases expression
protein 18951874
D013806 51569 UFM1
BM-002
C13orf20
ubiquitin-fold modifier 1 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of UFM1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 7366 UGT2B15
HLUG4
UDPGT_2B8
UDPGT2B15
UDPGTH3
UGT2B8
UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) Theophylline results in decreased expression of UGT2B15 mRNA decreases expression
mRNA 16083514
D013806 84135 UTP15
NET21
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) Theophylline results in increased expression of UTP15 mRNA increases expression
mRNA 18951874
D013806 7405 UVRAG
DHTX
VPS38
p63
UV radiation resistance associated [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of UVRAG protein affects cotreatment
/ decreases expression
protein 18951874
D013806 7424 VEGFC
Flt4-L
VRP
vascular endothelial growth factor C Theophylline results in increased expression of VEGFC mRNA increases expression
mRNA 16083514
D013806 9559 VPS26A
HB58
Hbeta58
PEP8A
VPS26
vacuolar protein sorting 26 homolog A (S. pombe) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of VPS26A protein affects cotreatment
/ increases expression
protein 18951874
D013806 30813 VSX1
CAASDS
KTCN
KTCN1
PPCD
PPD
RINX
visual system homeobox 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of VSX1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 81554 WBSCR16
Williams-Beuren syndrome chromosome region 16 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of WBSCR16 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 91833 WDR20
DMR
WD repeat domain 20 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of WDR20 protein affects cotreatment
/ increases expression
protein 18951874
D013806 55093 WDYHV1
C8orf32
WDYHV motif containing 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of WDYHV1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 339005 WHAMMP3
WHAMML1
WHDC1L1
WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 3 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of WHAMMP3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 54904 WHSC1L1
NSD3
pp14328
Wolf-Hirschhorn syndrome candidate 1-like 1 (EC:2.1.1.43) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of WHSC1L1 protein affects cotreatment
/ increases expression
protein 18951874
D013806 9589 WTAP
Wilms tumor 1 associated protein [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of WTAP protein affects cotreatment
/ increases expression
protein 18951874
D013806 51741 WWOX
D16S432E
FOR
FRA16D
HHCMA56
PRO0128
SDR41C1
WOX1
WW domain containing oxidoreductase (EC:1.1.1.-) [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of WWOX protein affects cotreatment
/ decreases expression
protein 18951874
D013806 51741 WWOX
D16S432E
FOR
FRA16D
HHCMA56
PRO0128
SDR41C1
WOX1
WW domain containing oxidoreductase (EC:1.1.1.-) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of WWOX protein affects cotreatment
/ increases expression
protein 18951874
D013806 331 XIAP
API3
BIRC4
IAP-3
ILP1
MIHA
XLP2
hIAP-3
hIAP3
X-linked inhibitor of apoptosis Theophylline results in increased expression of XIAP mRNA increases expression
mRNA 18951874
D013806 9942 XYLB
xylulokinase homolog (H. influenzae) (EC:2.7.1.17) [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of XYLB protein affects cotreatment
/ increases expression
protein 18951874
D013806 10413 YAP1
YAP
YAP2
YAP65
YKI
Yes-associated protein 1 Theophylline results in decreased expression of YAP1 mRNA decreases expression
mRNA 18951874
D013806 84272 YIPF4
FinGER4
Yip1 domain family, member 4 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of YIPF4 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 286451 YIPF6
FinGER6
Yip1 domain family, member 6 Theophylline results in increased expression of YIPF6 mRNA increases expression
mRNA 18951874
D013806 91746 YTHDC1
YT521
YT521-B
YTH domain containing 1 Theophylline results in increased expression of YTHDC1 mRNA increases expression
mRNA 18951874
D013806 10472 ZBTB18
C2H2-171
RP58
TAZ-1
ZNF238
zinc finger and BTB domain containing 18 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ZBTB18 protein affects cotreatment
/ increases expression
protein 18951874
D013806 7597 ZBTB25
C14orf51
KUP
ZNF46
zinc finger and BTB domain containing 25 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZBTB25 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 84878 ZBTB45
ZNF499
zinc finger and BTB domain containing 45 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZBTB45 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 54819 ZCCHC10
zinc finger, CCHC domain containing 10 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZCCHC10 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 79844 ZDHHC11
ZNF399
zinc finger, DHHC-type containing 11 (EC:2.3.1.225) Theophylline results in decreased expression of ZDHHC11 mRNA decreases expression
mRNA 18951874
D013806 60685 ZFAND3
TEX27
zinc finger, AN1-type domain 3 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ZFAND3 protein affects cotreatment
/ increases expression
protein 18951874
D013806 7542 ZFPL1
D11S750
MCG4
zinc finger protein-like 1 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZFPL1 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 7572 ZNF24
KOX17
RSG-A
ZNF191
ZSCAN3
Zfp191
zinc finger protein 24 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZNF24 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 7574 ZNF26
KOX20
zinc finger protein 26 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZNF26 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 6940 ZNF354A
EZNF
HKL1
KID-1
KID1
TCF17
zinc finger protein 354A [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZNF354A protein affects cotreatment
/ decreases expression
protein 18951874
D013806 22869 ZNF510
zinc finger protein 510 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ZNF510 protein affects cotreatment
/ increases expression
protein 18951874
D013806 147947 ZNF542
zinc finger protein 542 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZNF542 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 424158 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ZNF650 protein affects cotreatment
/ increases expression
protein 18951874
D013806 90592 ZNF700
zinc finger protein 700 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZNF700 protein affects cotreatment
/ decreases expression
protein 18951874
D013806 8233 ZRSR2
U2AF1-RS2
U2AF1L2
U2AF1RS2
URP
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 Theophylline results in decreased expression of ZRSR2 mRNA decreases expression
mRNA 18951874
D013806 79364 ZXDC
ZXDL
ZXD family zinc finger C [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ZXDC protein affects cotreatment
/ increases expression
protein 18951874

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (55)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#614613 Acrodysostosis 2, with or without hormone resistance; acrdys2 Q08499
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#103780 Alcohol dependence P08172
P14416
P31645
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#300615 Brunner syndrome P21397
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#607208 Dravet syndrome P35498
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#613721 Epileptic encephalopathy, early infantile, 11; eiee11 Q99250
#615363 Estrogen resistance; estrr P03372
#612219 Ewing sarcoma; es P11308
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#604403 Generalized epilepsy with febrile seizures plus, type 2; gefsp2 P35498
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 O75874
P04626
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
Q9Y6L6
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#603932 Intervertebral disc disease; idd P14780
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
#174800 Mccune-albright syndrome; mas P63092
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#609634 Migraine, familial hemiplegic, 3; fhm3 P35498
#126200 Multiple sclerosis, susceptibility to; ms P08575
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#607276 Resting heart rate, variation in P08588
#607745 Seizures, benign familial infantile, 3; bfis3 Q99250
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#190300 Tremor, hereditary essential, 1; etm1 P35462
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303

KEGG DISEASE (42)

KEGG disease name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00213 Hypophosphatasia P05186 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H01205 Coumarin resistance P11712 (related)
H00025 Penile cancer P14780 (related)
P35354 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00548 Brunner syndrome P21397 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00775 Familial or sporadic hemiplegic migraine P35498 (related)
H00783 Febrile seizures P35498 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00606 Early infantile epileptic encephalopathy Q99250 (related)
H00806 Benign familial neonatal and infantile epilepsies Q99250 (related)

Diseases related to CTD interactions

123 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D000138 D013806 Acidosis marker/mechanism
3769383
6506685
D058186 D013806 Acute Kidney Injury marker/mechanism
therapeutic
1956491
2858780
10441997
C538231 D013806 Adenocarcinoma of lung marker/mechanism
11079726
D000402 D013806 Airway Obstruction therapeutic
8760775
D001018 D013806 Aortic Diseases marker/mechanism
2251542
D001049 D013806 Apnea therapeutic
22592
683202
718247
723879
4014092
7055114
7398750
D001145 D013806 Arrhythmias, Cardiac marker/mechanism
2222089
2438095
3330186
6506685
7826681
10326941
18724532
D001167 D013806 Arteritis marker/mechanism
8572928
9879811
12180796
D001247 D013806 Asthenia therapeutic
8237803
D001249 D013806 Asthma therapeutic
208429
1424400
1758745
2496015
2578971
2828249
3025113
3074291
3109801
3523664
3537092
3707814
6586482
7140872
7148765
7235434
7312482
7332913
7437783
8162974
8346082
8760775
9701106
9878995
10596698
10916367
11758890
11951074
12070353
12113382
12355682
12734767
15370247
15645133
16083514
16270722
16430859
16569937
17130682
17943569
D001927 D013806 Brain Diseases marker/mechanism
8517990
D001930 D013806 Brain Injuries marker/mechanism
10565195
D001986 D013806 Bronchial Spasm therapeutic
6187071
15012710
D001991 D013806 Bronchitis therapeutic
3025113
D029481 D013806 Bronchitis, Chronic therapeutic
18326306
D009202 D013806 Cardiomyopathies therapeutic
2432914
D002318 D013806 Cardiovascular Diseases marker/mechanism
1835291
D002375 D013806 Catalepsy therapeutic
1865993
3167148
9407998
9566031
10199625
10591873
11734184
20713114
D002543 D013806 Cerebral Hemorrhage marker/mechanism
3949080
D002637 D013806 Chest Pain therapeutic
12498299
15238202
D002653 D013806 Child Behavior Disorders marker/mechanism
1758745
D002819 D013806 Chorea marker/mechanism
1424400
D019970 D013806 Cocaine-Related Disorders marker/mechanism
11927167
D003128 D013806 COMA marker/mechanism
6858124
D017714 D013806 Community-Acquired Infections therapeutic
1541177
D003221 D013806 Confusion marker/mechanism
637435
3769383
6625253
D003693 D013806 Delirium marker/mechanism
6506685
D003866 D013806 Depressive Disorder marker/mechanism
7437783
D004310 D013806 Double Outlet Right Ventricle marker/mechanism
2251542
D062787 D013806 Drug Overdose marker/mechanism
108053
10326941
10565195
11605782
D064420 D013806 Drug-Related Side Effects and Adverse Reactions marker/mechanism
therapeutic
2189301
3792059
6121526
7270562
8959032
D004409 D013806 Dyskinesia, Drug-Induced marker/mechanism
6625253
D004417 D013806 Dyspnea therapeutic
6858124
D004487 D013806 Edema marker/mechanism
22982570
D004646 D013806 Emphysema therapeutic
9788033
11408986
D004830 D013806 Epilepsy, Tonic-Clonic marker/mechanism
823660
2360338
D004935 D013806 Esophageal Diseases therapeutic
12498299
D020329 D013806 Essential Tremor therapeutic
1946576
D005119 D013806 Extravasation of Diagnostic and Therapeutic Materials therapeutic
11522602
D005221 D013806 Fatigue marker/mechanism
3769383
D005334 D013806 Fever marker/mechanism
20940509
D005767 D013806 Gastrointestinal Diseases marker/mechanism
1835291
7826681
9164358
D006029 D013806 Glycosuria marker/mechanism
718247
D006212 D013806 Hallucinations marker/mechanism
17516267
D006261 D013806 Headache marker/mechanism
6386511
6838301
D006319 D013806 Hearing Loss, Sensorineural marker/mechanism
3627078
D006323 D013806 Heart Arrest therapeutic
10628632
D006327 D013806 Heart Block therapeutic
1874263
D006330 D013806 Heart Defects, Congenital marker/mechanism
2251542
D006470 D013806 Hemorrhage marker/mechanism
22982570
D006519 D013806 Hepatitis, Alcoholic therapeutic
20578267
D006930 D013806 Hyperalgesia marker/mechanism
7908645
D006934 D013806 Hypercalcemia therapeutic
3013062
17578191
D053565 D013806 Hypercalciuria marker/mechanism
8407166
D006940 D013806 Hyperemia therapeutic
2348231
19496111
D006943 D013806 Hyperglycemia marker/mechanism
718247
1445173
6506685
D006948 D013806 Hyperkinesis marker/mechanism
15351080
D006973 D013806 Hypertension marker/mechanism
therapeutic
10230855
18416941
D006984 D013806 Hypertrophy marker/mechanism
16651698
D007008 D013806 Hypokalemia marker/mechanism
2596942
2973024
3330186
3408637
3662713
3707814
3940495
6506685
8177851
18724532
D018476 D013806 Hypokinesia marker/mechanism
11734184
D007010 D013806 Hyponatremia marker/mechanism
8177851
12086552
D017674 D013806 Hypophosphatemia marker/mechanism
6506685
D007022 D013806 Hypotension marker/mechanism
therapeutic
1746998
3706053
3994078
6506685
16595736
D007174 D013806 Impulse Control Disorders marker/mechanism
6093179
D007177 D013806 Inappropriate ADH Syndrome marker/mechanism
12086552
D007232 D013806 Infant, Newborn, Diseases therapeutic
7055114
D007235 D013806 Infant, Premature, Diseases marker/mechanism
therapeutic
22592
660340
7398750
11605782
D007248 D013806 Infertility, Male marker/mechanism
16988215
D007249 D013806 Inflammation therapeutic
12065913
12070353
D007674 D013806 Kidney Diseases marker/mechanism
therapeutic
7892462
12745095
12836095
16714461
D007859 D013806 Learning Disorders marker/mechanism
15351080
D053609 D013806 Lethargy marker/mechanism
3769383
D015451 D013806 Leukemia, Lymphocytic, Chronic, B-Cell therapeutic
15370247
D007945 D013806 Leukemia, Lymphoid therapeutic
11128117
D007964 D013806 Leukocytosis marker/mechanism
20940509
D008173 D013806 Lung Diseases, Obstructive therapeutic
7053695
D008175 D013806 Lung Neoplasms therapeutic
17459420
D008569 D013806 Memory Disorders marker/mechanism
15351080
D008659 D013806 Metabolic Diseases marker/mechanism
15012710
D019964 D013806 Mood Disorders marker/mechanism
3537092
D016183 D013806 Murine Acquired Immunodeficiency Syndrome therapeutic
11694023
D009127 D013806 Muscle Rigidity marker/mechanism
8865732
D017202 D013806 Myocardial Ischemia therapeutic
3257531
D009212 D013806 Myoglobinuria marker/mechanism
8865732
D009325 D013806 Nausea marker/mechanism
2218006
3074291
3537092
6506685
16868215
D009362 D013806 Neoplasm Metastasis therapeutic
11095404
D009374 D013806 Neoplasms, Experimental therapeutic
11095404
D009422 D013806 Nervous System Diseases marker/mechanism
2038423
3949080
D000857 D013806 Olfaction Disorders therapeutic
9754114
D009846 D013806 Oliguria therapeutic
15840666
D010409 D013806 Penile Diseases therapeutic
8745169
D011014 D013806 Pneumonia therapeutic
1541177
D051299 D013806 Post-Dural Puncture Headache therapeutic
12799921
D011297 D013806 Prenatal Exposure Delayed Effects marker/mechanism
2251542
D011595 D013806 Psychomotor Agitation marker/mechanism
6288396
D029424 D013806 Pulmonary Disease, Chronic Obstructive therapeutic
1546832
1835291
2218006
2969553
6288396
6858124
8888546
9756159
16430859
17130682
18983928
20578267
20797314
D051437 D013806 Renal Insufficiency marker/mechanism
3494838
D015427 D013806 Reperfusion Injury therapeutic
16410406
D012120 D013806 Respiration Disorders therapeutic
2636852
D012133 D013806 Respiratory Paralysis therapeutic
12821393
D012206 D013806 Rhabdomyolysis marker/mechanism
2858780
7826681
10441997
D012640 D013806 Seizures marker/mechanism
therapeutic
237450
637435
1312320
1438500
1676814
1866026
1901667
2079649
2087497
2222089
2496015
2600817
2623258
2786601
2965587
2969553
3177989
3188359
3225766
3494838
3626650
3723646
3922683
3994071
6646925
6858124
7148765
7270562
7824546
8007033
8046614
8048709
8179767
8192750
8346082
8437130
8540225
8799489
9294318
9339868
9717943
10211593
10230855
10326941
10401785
10819670
10874349
10916367
11734184
16715938
17072109
17671412
17784538
18279214
18326306
18520175
19589454
20940509
D012893 D013806 Sleep Disorders marker/mechanism
1776216
2520495
D012912 D013806 Sneezing therapeutic
2417477
2431021
D013035 D013806 Spasm therapeutic
9658871
D013036 D013806 Spasms, Infantile marker/mechanism
7756814
D046628 D013806 Sphincter of Oddi Dysfunction therapeutic
9658871
D013119 D013806 Spinal Cord Injuries therapeutic
12426040
12821393
14992338
D013163 D013806 Splenomegaly therapeutic
11694023
D013226 D013806 Status Epilepticus marker/mechanism
108053
637435
1541177
2038423
11605782
18634420
19911151
D013342 D013806 Stuttering marker/mechanism
7312482
7882883
9756159
D013375 D013806 Substance Withdrawal Syndrome marker/mechanism
7055114
D019462 D013806 Syncope, Vasovagal therapeutic
1746998
D013610 D013806 Tachycardia marker/mechanism
2623258
2856947
3408637
4014092
6625253
6751238
7270562
8346082
8888546
10230855
11408986
16868215
D013614 D013806 Tachycardia, Paroxysmal marker/mechanism
660340
D013616 D013806 Tachycardia, Sinus marker/mechanism
7826681
11483122
D013617 D013806 Tachycardia, Supraventricular marker/mechanism
660340
D014188 D013806 Transposition of Great Vessels marker/mechanism
2251542
D014202 D013806 Tremor marker/mechanism
1424400
3074291
6288396
6313028
6506685
6586482
7140872
8017343
D014549 D013806 Urinary Incontinence marker/mechanism
3769383
D016055 D013806 Urinary Retention marker/mechanism
6187071
7235434
7469216
D014839 D013806 Vomiting marker/mechanism
2218006
3074291
6625253
8346082
8888546
16868215