PCIDB

KNApSAcK Metabolite C00001519

Metabolite

KNApSAcK Entry

id C00001519
Name Phalloidin
CAS RN 17466-45-4
Standard InChI InChI=1S/C35H48N8O11S/c1-15-27(47)38-22-10-20-19-7-5-6-8-21(19)41-33(20)55-13-24(34(53)43-12-18(46)9-25(43)31(51)37-15)40-32(52)26(17(3)45)42-28(48)16(2)36-30(50)23(39-29(22)49)11-35(4,54)14-44/h5-8,15-18,22-26,41,44-46,54H,9-14H2,1-4H3,(H,36,50)(H,37,51)(H,38,47)(H,39,49)(H,40,52)(H,42,48)/t15-,16-,17-,18-,22-,23-,24-,25-,26+,35+/m0/s1
Standard InChI (Main Layer) InChI=1S/C35H48N8O11S/c1-15-27(47)38-22-10-20-19-7-5-6-8-21(19)41-33(20)55-13-24(34(53)43-12-18(46)9-25(43)31(51)37-15)40-32(52)26(17(3)45)42-28(48)16(2)36-30(50)23(39-29(22)49)11-35(4,54)14-44/h5-8,15-18,22-26,41,44-46,54H,9-14H2,1-4H3,(H,36,50)(H,37,51)(H,38,47)(H,39,49)(H,40,52)(H,42,48)

Cluster

Phytochemical cluster
KCF-S cluster No. 3240

Link

ChEMBL

By standard InChI
By standard InChI Main Layer

KEGG

By LinkDB C08439

CTD

By CAS RN D010590

Species

Summary

Plant class

class name count

Family

family name count
Amanitaceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Amanita phalloides 67723 Amanitaceae Fungi
Amanita virosa 78357 Amanitaceae Fungi

Human Protein / Gene in interaction

CTD interaction (3)

compound gene gene name gene description interaction interaction type form reference
pmid
D010590 10599 SLCO1B1
HBLRR
LST-1
LST1
OATP-C
OATP1B1
OATP2
OATPC
SLC21A6
solute carrier organic anion transporter family, member 1B1 Bile Acids and Salts inhibits the reaction [SLCO1B1 protein results in increased uptake of Phalloidine] decreases reaction
/ increases uptake
protein 19464309
D010590 10599 SLCO1B1
HBLRR
LST-1
LST1
OATP-C
OATP1B1
OATP2
OATPC
SLC21A6
solute carrier organic anion transporter family, member 1B1 SLCO1B1 protein results in increased uptake of Phalloidine increases uptake
protein 19464309
D010590 28234 SLCO1B3
HBLRR
LST-2
LST-3TM13
LST3
OATP-8
OATP1B3
OATP8
SLC21A8
solute carrier organic anion transporter family, member 1B3 SLCO1B3 protein results in increased uptake of Phalloidine increases uptake
protein 19464309

Related Disease

Diseases related to CTD interactions

4 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D002779 D010590 Cholestasis marker/mechanism
18296417
19409403
D006417 D010590 Hematuria marker/mechanism
19409403
D007674 D010590 Kidney Diseases marker/mechanism
19409403
D009336 D010590 Necrosis marker/mechanism
19409403