id | C00001550 |
---|---|
Name | Pantothenic acid |
CAS RN | 79-83-4 |
Standard InChI | InChI=1S/C9H17NO5/c1-9(2,5-11)7(14)8(15)10-4-3-6(12)13/h7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13)/t7-/m0/s1 |
Standard InChI (Main Layer) | InChI=1S/C9H17NO5/c1-9(2,5-11)7(14)8(15)10-4-3-6(12)13/h7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13) |
Phytochemical cluster | |
---|---|
KCF-S cluster | No. 4566 |
By standard InChI | CHEMBL1594 |
---|---|
By standard InChI Main Layer | CHEMBL1594 CHEMBL1741144 CHEMBL2110806 |
By LinkDB | C00864 |
---|
By CAS RN | D010205 |
---|
class name | count |
---|---|
rosids | 1 |
family name | count |
---|---|
Enterobacteriaceae | 1 |
Brassicaceae | 1 |
KNApSAcK organism | *ID | *family | *plant class | *kingdom |
---|---|---|---|---|
Arabidopsis thaliana | 3702 | Brassicaceae | rosids | Viridiplantae |
Escherichia coli | 562 | Enterobacteriaceae | Bacteria |
compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
---|---|---|---|---|---|---|---|
D010205 | 84913 |
ATOH8
HATH6 bHLHa21 |
atonal homolog 8 (Drosophila) | Pantothenic Acid results in increased expression of ATOH8 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 51250 |
C6orf203
PRED31 RP11-59I9.1 |
chromosome 6 open reading frame 203 | Pantothenic Acid results in increased expression of C6ORF203 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | Pantothenic Acid results in increased expression of CYP1B1 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 131583 |
FAM43A
|
family with sequence similarity 43, member A | Pantothenic Acid results in increased expression of FAM43A mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 2529 |
FUT7
FucT-VII |
fucosyltransferase 7 (alpha (1,3) fucosyltransferase) (EC:2.4.1.-) | Pantothenic Acid results in decreased expression of FUT7 mRNA |
decreases expression
|
mRNA |
19397697
|
D010205 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Pantothenic Acid results in increased expression of HMOX1 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Pantothenic Acid results in increased expression of HMOX1 protein |
increases expression
|
protein |
19397697
|
D010205 | 27129 |
HSPB7
cvHSP |
heat shock 27kDa protein family, member 7 (cardiovascular) | Pantothenic Acid results in increased expression of HSPB7 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 3397 |
ID1
ID bHLHb24 |
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | Pantothenic Acid results in increased expression of ID1 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 3399 |
ID3
HEIR-1 bHLHb25 |
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | Pantothenic Acid results in increased expression of ID3 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | Pantothenic Acid results in increased expression of IL6 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Pantothenic Acid results in increased expression of IL8 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 386682 |
KRTAP10-3
KAP10.3 KAP18-3 KAP18.3 KRTAP10.3 KRTAP18-3 KRTAP18.3 |
keratin associated protein 10-3 | Pantothenic Acid results in decreased expression of KRTAP10-3 mRNA |
decreases expression
|
mRNA |
19397697
|
D010205 | 51257 |
MARCH2
MARCH-II RNF172 |
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase (EC:6.3.2.-) | Pantothenic Acid results in increased expression of MARCH2 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 4613 |
MYCN
MODED MYCNOT N-myc NMYC ODED bHLHe37 |
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | Pantothenic Acid results in increased expression of MYCN mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 378884 |
NHLRC1
EPM2A EPM2B MALIN bA204B7.2 |
NHL repeat containing 1 | Pantothenic Acid results in increased expression of NHLRC1 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 9315 |
NREP
C5orf13 D4S114 P311 PRO1873 PTZ17 SEZ17 |
neuronal regeneration related protein | Pantothenic Acid results in increased expression of NREP mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 5456 |
POU3F4
BRAIN-4 BRN-4 BRN4 DFN3 DFNX2 OCT-9 OTF-9 OTF9 |
POU class 3 homeobox 4 | Pantothenic Acid results in increased expression of POU3F4 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 5790 |
PTPRCAP
CD45-AP LPAP |
protein tyrosine phosphatase, receptor type, C-associated protein | Pantothenic Acid results in increased expression of PTPRCAP mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 645683 |
RPL13AP3
RPL13A_11_1370 |
ribosomal protein L13a pseudogene 3 | Pantothenic Acid results in increased expression of RPL13AP3 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 123264 |
SLC51B
OSTB OSTBETA |
solute carrier family 51, beta subunit | Pantothenic Acid results in increased expression of SLC51B mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 8884 |
SLC5A6
SMVT |
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | SLC5A6 results in increased transport of Pantothenic Acid |
increases transport
|
10329687
|
|
D010205 | 8884 |
SLC5A6
SMVT |
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | Sodium affects the reaction [SLC5A6 results in increased transport of Pantothenic Acid] |
affects reaction
/ increases transport |
10329687
|
|
D010205 | 6657 |
SOX2
ANOP3 MCOPS3 |
SRY (sex determining region Y)-box 2 | Pantothenic Acid results in decreased expression of SOX2 mRNA |
decreases expression
|
mRNA |
19397697
|
D010205 | 129787 |
TMEM18
|
transmembrane protein 18 | Pantothenic Acid results in increased expression of TMEM18 mRNA |
increases expression
|
mRNA |
19397697
|
D010205 | 284346 |
ZNF575
|
zinc finger protein 575 | Pantothenic Acid results in decreased expression of ZNF575 mRNA |
decreases expression
|
mRNA |
19397697
|
MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
---|---|---|---|---|---|
D000014 | D010205 | Abnormalities, Drug-Induced |
therapeutic
|
16112698
|
|
D064420 | D010205 | Drug-Related Side Effects and Adverse Reactions |
therapeutic
|
17379144
|
|
D009369 | D010205 | Neoplasms |
therapeutic
|
6061664
|
|
D009436 | D010205 | Neural Tube Defects |
therapeutic
|
8638254
16112698 |
|
D049188 | D010205 | Prenatal Injuries |
therapeutic
|
16112698
|
|
D014949 | D010205 | Wounds, Nonpenetrating |
therapeutic
|
19397697
|