Metabolite

KNApSAcK Entry

id C00001550
Name Pantothenic acid
CAS RN 79-83-4
Standard InChI InChI=1S/C9H17NO5/c1-9(2,5-11)7(14)8(15)10-4-3-6(12)13/h7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13)/t7-/m0/s1
Standard InChI (Main Layer) InChI=1S/C9H17NO5/c1-9(2,5-11)7(14)8(15)10-4-3-6(12)13/h7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13)

Cluster

Phytochemical cluster
KCF-S cluster No. 4566

Link

ChEMBL

By standard InChI CHEMBL1594
By standard InChI Main Layer CHEMBL1594 CHEMBL1741144 CHEMBL2110806

KEGG

By LinkDB C00864

CTD

By CAS RN D010205

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Enterobacteriaceae 1
Brassicaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Escherichia coli 562 Enterobacteriaceae Bacteria

Human Protein / Gene in interaction

CTD interaction (26)

compound gene gene name gene description interaction interaction type form reference
pmid
D010205 84913 ATOH8
HATH6
bHLHa21
atonal homolog 8 (Drosophila) Pantothenic Acid results in increased expression of ATOH8 mRNA increases expression
mRNA 19397697
D010205 51250 C6orf203
PRED31
RP11-59I9.1
chromosome 6 open reading frame 203 Pantothenic Acid results in increased expression of C6ORF203 mRNA increases expression
mRNA 19397697
D010205 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Pantothenic Acid results in increased expression of CYP1B1 mRNA increases expression
mRNA 19397697
D010205 131583 FAM43A
family with sequence similarity 43, member A Pantothenic Acid results in increased expression of FAM43A mRNA increases expression
mRNA 19397697
D010205 2529 FUT7
FucT-VII
fucosyltransferase 7 (alpha (1,3) fucosyltransferase) (EC:2.4.1.-) Pantothenic Acid results in decreased expression of FUT7 mRNA decreases expression
mRNA 19397697
D010205 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Pantothenic Acid results in increased expression of HMOX1 mRNA increases expression
mRNA 19397697
D010205 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Pantothenic Acid results in increased expression of HMOX1 protein increases expression
protein 19397697
D010205 27129 HSPB7
cvHSP
heat shock 27kDa protein family, member 7 (cardiovascular) Pantothenic Acid results in increased expression of HSPB7 mRNA increases expression
mRNA 19397697
D010205 3397 ID1
ID
bHLHb24
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein Pantothenic Acid results in increased expression of ID1 mRNA increases expression
mRNA 19397697
D010205 3399 ID3
HEIR-1
bHLHb25
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein Pantothenic Acid results in increased expression of ID3 mRNA increases expression
mRNA 19397697
D010205 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Pantothenic Acid results in increased expression of IL6 mRNA increases expression
mRNA 19397697
D010205 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Pantothenic Acid results in increased expression of IL8 mRNA increases expression
mRNA 19397697
D010205 386682 KRTAP10-3
KAP10.3
KAP18-3
KAP18.3
KRTAP10.3
KRTAP18-3
KRTAP18.3
keratin associated protein 10-3 Pantothenic Acid results in decreased expression of KRTAP10-3 mRNA decreases expression
mRNA 19397697
D010205 51257 MARCH2
MARCH-II
RNF172
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase (EC:6.3.2.-) Pantothenic Acid results in increased expression of MARCH2 mRNA increases expression
mRNA 19397697
D010205 4613 MYCN
MODED
MYCNOT
N-myc
NMYC
ODED
bHLHe37
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog Pantothenic Acid results in increased expression of MYCN mRNA increases expression
mRNA 19397697
D010205 378884 NHLRC1
EPM2A
EPM2B
MALIN
bA204B7.2
NHL repeat containing 1 Pantothenic Acid results in increased expression of NHLRC1 mRNA increases expression
mRNA 19397697
D010205 9315 NREP
C5orf13
D4S114
P311
PRO1873
PTZ17
SEZ17
neuronal regeneration related protein Pantothenic Acid results in increased expression of NREP mRNA increases expression
mRNA 19397697
D010205 5456 POU3F4
BRAIN-4
BRN-4
BRN4
DFN3
DFNX2
OCT-9
OTF-9
OTF9
POU class 3 homeobox 4 Pantothenic Acid results in increased expression of POU3F4 mRNA increases expression
mRNA 19397697
D010205 5790 PTPRCAP
CD45-AP
LPAP
protein tyrosine phosphatase, receptor type, C-associated protein Pantothenic Acid results in increased expression of PTPRCAP mRNA increases expression
mRNA 19397697
D010205 645683 RPL13AP3
RPL13A_11_1370
ribosomal protein L13a pseudogene 3 Pantothenic Acid results in increased expression of RPL13AP3 mRNA increases expression
mRNA 19397697
D010205 123264 SLC51B
OSTB
OSTBETA
solute carrier family 51, beta subunit Pantothenic Acid results in increased expression of SLC51B mRNA increases expression
mRNA 19397697
D010205 8884 SLC5A6
SMVT
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 SLC5A6 results in increased transport of Pantothenic Acid increases transport
10329687
D010205 8884 SLC5A6
SMVT
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 Sodium affects the reaction [SLC5A6 results in increased transport of Pantothenic Acid] affects reaction
/ increases transport
10329687
D010205 6657 SOX2
ANOP3
MCOPS3
SRY (sex determining region Y)-box 2 Pantothenic Acid results in decreased expression of SOX2 mRNA decreases expression
mRNA 19397697
D010205 129787 TMEM18
transmembrane protein 18 Pantothenic Acid results in increased expression of TMEM18 mRNA increases expression
mRNA 19397697
D010205 284346 ZNF575
zinc finger protein 575 Pantothenic Acid results in decreased expression of ZNF575 mRNA decreases expression
mRNA 19397697

Related Disease

Diseases related to CTD interactions

6 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D000014 D010205 Abnormalities, Drug-Induced therapeutic
16112698
D064420 D010205 Drug-Related Side Effects and Adverse Reactions therapeutic
17379144
D009369 D010205 Neoplasms therapeutic
6061664
D009436 D010205 Neural Tube Defects therapeutic
8638254
16112698
D049188 D010205 Prenatal Injuries therapeutic
16112698
D014949 D010205 Wounds, Nonpenetrating therapeutic
19397697