KNApSAcK Metabolite C00016021
Metabolite
KNApSAcK Entry
| id | C00016021 |
|---|---|
| Name | Precose / Glucobay / Acarbose / Prandase / Ascarbose / BAY-g 5421 |
| CAS RN | 56180-94-0 |
| Standard InChI | InChI=1S/C25H43NO18/c1-7-13(26-9-2-8(3-27)14(33)18(37)15(9)34)17(36)20(39)24(41-7)44-23-12(6-30)42-25(21(40)19(23)38)43-22(11(32)5-29)16(35)10(31)4-28/h2,4,7,9-27,29-40H,3,5-6H2,1H3/t7-,9+,10+,11-,12-,13?,14-,15+,16-,17+,18+,19-,20-,21-,22-,23-,24?,25-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C25H43NO18/c1-7-13(26-9-2-8(3-27)14(33)18(37)15(9)34)17(36)20(39)24(41-7)44-23-12(6-30)42-25(21(40)19(23)38)43-22(11(32)5-29)16(35)10(31)4-28/h2,4,7,9-27,29-40H,3,5-6H2,1H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 772 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer |
KEGG
| By LinkDB | C06802 |
|---|
CTD
| By CAS RN | D020909 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Micromonosporaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Actinoplanes sp. | 1871 | Micromonosporaceae | Bacteria |
Human Protein / Gene in interaction
CTD interaction (2)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D020909 | 8972 |
MGAM
MG MGA |
maltase-glucoamylase (alpha-glucosidase) (EC:3.2.1.20 3.2.1.3) | Acarbose results in decreased activity of MGAM protein |
decreases activity
|
protein |
20349118
|
| D020909 | 10891 |
PPARGC1A
LEM6 PGC-1(alpha) PGC-1v PGC1 PGC1A PPARGC1 |
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | PPARGC1A protein polymorphism affects the susceptibility to Acarbose |
affects response to substance
|
protein |
15592662
|
Related Disease
Diseases related to CTD interactions
12 disease from interactions of metabolites
| MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
|---|---|---|---|---|---|
| D002312 | D020909 | Cardiomyopathy, Hypertrophic |
therapeutic
|
20703014
|
|
| D002318 | D020909 | Cardiovascular Diseases |
therapeutic
|
17133782
|
|
| D003924 | D020909 | Diabetes Mellitus, Type 2 |
therapeutic
|
15592662
|
|
| D056486 | D020909 | Drug-Induced Liver Injury |
marker/mechanism
|
15324623
|
|
| D004719 | D020909 | Endomyocardial Fibrosis |
therapeutic
|
20703014
|
|
| D005234 | D020909 | Fatty Liver |
therapeutic
|
14975757
19207582 |
|
| D005770 | D020909 | Gastrointestinal Neoplasms |
therapeutic
|
9617344
|
|
| D006943 | D020909 | Hyperglycemia |
therapeutic
|
20667563
|
|
| D007249 | D020909 | Inflammation |
therapeutic
|
14975757
|
|
| D017114 | D020909 | Liver Failure, Acute |
marker/mechanism
|
18648179
|
|
| C541083 | D020909 | Non-alcoholic Fatty Liver Disease |
therapeutic
|
14975757
|
|
| D009765 | D020909 | Obesity |
therapeutic
|
19207582
|